Frontiers in Cardiovascular Medicine

DECEMBER 9, 2024

BackgroundLow-Density Lipoprotein Cholesterol (LDL-C) is the primary lipid therapy target for coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI). Employing Multivariate Cox regression analysis, we assessed the correlation between RLP-C and NTLs progression.

Cholesterol 98

Cholesterol Coronary Artery Disease Atherosclerosis Diabetes 98

Journal of Clinical Investigation - Cardiology

MARCH 1, 2024

This interaction led to increased cytosolic cholesterol in macrophages and changes in expression of lipid metabolism genes consistent with increased cholesterol uptake.

Atherosclerosis 122

Atherosclerosis Cholesterol Cardiovascular Disease Plaque 122

Circulation

JANUARY 27, 2025

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Frontiers in Cardiovascular Medicine

MARCH 21, 2024

Introduction The progression of coronary atherosclerosis is an active and regulated process. The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.

Atherosclerosis 64

Atherosclerosis Plaque Cholesterol Cardiovascular Disease 64

Science Daily - Heart Disease

FEBRUARY 19, 2024

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.

Heart Disease 119

Heart Disease Heart Attack Heart attacks Atherosclerosis 119

The British Journal of Cardiology

DECEMBER 3, 2024

This year, the cholesterol charity took on an international theme, looking at the global cardiovascular disease (CVD) prevention picture. HEART UK held its 37 th Annual Medical and Scientific Conference between 10 th –12 th July.

Cardiovascular Disease 40

Cardiovascular Disease Atherosclerosis Cholesterol 40

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundResolvin D2 (RvD2) has been reported to protect against the development of atherosclerosis in animal models. Mediation analysis was used to test the indirect effect of serum cholesterol indicators on the association between RvD2 and ASCVD probability. Journal of the American Heart Association, Ahead of Print. P<0.001).

Cholesterol 63

Cholesterol Cardiovascular Disease Atherosclerosis Outcomes 63

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Positive correlations were identified with age, systolic blood pressure, a history of hypertension, male gender, and total cholesterol. By stressing the significance of managing cholesterol levels, especially HDL, our findings provide actionable insights for CAS prevention.

Atherosclerosis 52

Atherosclerosis Cholesterol Blood Pressure Risk Factors 52

DAIC

AUGUST 15, 2024

13, 2024 – The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study led by UT Southwestern Medical Center researchers and published in JAMA Cardiology. Ann Marie Navar, M.D., tim.hodson Thu, 08/15/2024 - 10:32 Aug. population. Physicians following U.S.

Heart Disease 105

Heart Disease Research Cholesterol Public Health 105

HeartRhythm

OCTOBER 18, 2024

The relationship between remnant cholesterol (RC) and atrial fibrillation (AF) remains unclear.

Atrial Fibrillation 40

Atrial Fibrillation Cholesterol Atherosclerosis 40

Frontiers in Cardiovascular Medicine

JULY 16, 2024

cholesterol for 16 weeks. Atherosclerosis was evaluated at the endpoint of experiments. Plasma lipid levels, lipoproteins, and apolipoproteins were analyzed. Notably, both male (2.1-fold fold increase) and female (1.6-fold fold increase) apoE KO rabbits exhibited a significantly augmented aortic lesion area compared to WT controls.

Atherosclerosis 52

Atherosclerosis Cholesterol Diet Aortic 52

Cardiovascular Diabetology

JULY 3, 2024

The abnormal low-density protein cholesterol (LDL-C) level in the development of atherosclerosis is often comorbid in individuals with type 2 diabetes mellitus(T2DM). This study aimed to investigate the aggrav.

Cholesterol 45

Cholesterol Diabetes Atherosclerosis Plaque 45

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. Small dense lowdensity lipoprotein cholesterol (sdLDLC) is considered as the most atherogenic lipoprotein. Journal of the American Heart Association, Ahead of Print.

Ultrasound 56

Ultrasound Plaque Cholesterol Coronary Artery Disease 56

HeartRhythm

NOVEMBER 18, 2024

Heart Rhtyhm recently published two large cohort studies, Chen et al, 2024, “Low remnant cholesterol and the subsequent risk of new-onset atrial fibrillation: A prospective cohort study” (1) and Ouyang, et al 2024, “Remnant Cholesterol and New-onset Atrial Fibrillation: The Atherosclerosis Risk in Communities Study” (2).

Atrial Fibrillation 40

Atrial Fibrillation Cholesterol Atherosclerosis 40

AMS Cardiology

JANUARY 21, 2023

We all want to be heart-healthy and ensuring our cholesterol levels are in the normal range is one of the most critical steps. High cholesterol can increase your risk of severe conditions like heart disease and heart attacks. Continue reading to learn four heart-healthy habits that can improve your cholesterol.

Cholesterol 40

Cholesterol Diet Blood Pressure Heart Attack 40

Dr. Paddy Barrett

FEBRUARY 27, 2024

Presence of atherosclerosis with LDL-C and HBA1c in the ‘normal range’ What the above graph shows is that for those with an LDL-C of 3.4 ‘Normal’ levels of risk factors such as blood pressure, cholesterol or blood glucose levels are often FAR from optimal. So far, two things should be very clear. JAMA Cardiol.

Risk Factors 112

Risk Factors Heart Disease Heart Attack Heart attacks 112

Circulation

NOVEMBER 11, 2024

CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Circulation

NOVEMBER 11, 2024

Introduction:It remains uncertain whether dietary supplementation of marine n-3 polyunsaturated fatty acids (PUFAs) improves atherosclerosis and lipoprotein subclasses in patients with type 2 diabetes (T2D). Circulation, Volume 150, Issue Suppl_1 , Page A4142898-A4142898, November 12, 2024. day) or low-dose (1.5g/day)

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Cholesterol 40

Dr. S. Venkatesan MD

OCTOBER 7, 2024

The enlightened thinking is, if LDL and HDL are brought around the same level of around 50mg , good and evil will have level playing ground , hoping goodness will win over the evil.Our vast vascular tree will have perfect lipid house keeping system and atherosclerosis will cease to occur.( Final message.

Cholesterol 40

Cholesterol Plaque Atherosclerosis Circulation 40

The New England Journal of Medicine

AUGUST 30, 2024

Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease.1

Cardiovascular Disease 60

Cardiovascular Disease Atherosclerosis Cholesterol 60

Cardiovascular Diabetology

JANUARY 21, 2025

Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis.

Coronary Artery Disease 52

Coronary Artery Disease Atherosclerosis Cholesterol Research 52

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. The resulting cholesterol crystals activate the NLRP3 (NOD‐like receptor protein 3) inflammasome, leading to inflammation and cardiovascular diseases. per 100 person‐years,P=0.01).

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

CTVS

SEPTEMBER 17, 2024

It is triggered by atherosclerosis, which occurs when fatty deposits or cholesterol accumulates… Source PAD is a serious condition affecting circulation and blood vessels, causing them to narrow from plaque buildup in the arteries and blocking blood flow to the extremities, typically the legs and feet.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Plaque Atherosclerosis Cholesterol 52

Dr. Paddy Barrett

NOVEMBER 7, 2023

The fundamental characteristic of atherosclerosis is when a cholesterol particle becomes trapped in the artery wall. It is the inflammatory response to this particle retention that causes the formation of atherosclerosis 1. Lipoprotein particles entering the subintimal space causing atherosclerosis. TG = Triglycerides.

Cholesterol 52

Cholesterol Atherosclerosis Stenosis Aortic 52

Circulation

NOVEMBER 11, 2024

Conclusions:There is an L-shaped association between NHHR levels and atherosclerosis in adults in the United States, and controlling NHHR is clinically important for reducing the risk of developing atherosclerosis. The cutoff value was 2.13, and in the hypertensive population, the cutoff value was 1.93.Conclusions:There

Cholesterol 40

Cholesterol Atherosclerosis Cardiovascular Disease Hypertension 40

Frontiers in Cardiovascular Medicine

DECEMBER 14, 2023

Background Inflammation and lipid infiltration play crucial roles in the development of atherosclerosis. The monocyte to high-density lipoprotein cholesterol ratio (MHR) was identified as a stronger independent risk factor for CHD.

Heart Disease 64

Heart Disease Cholesterol Stenosis Atherosclerosis 64

Frontiers in Cardiovascular Medicine

JULY 1, 2024

Statins are the primary drugs for treating hyperlipidemia or atherosclerosis, yet some patients remain unresponsive to them, and pregnant women are prohibited from taking statins. IntroductionThe incidence of metabolic disorders during pregnancy is increasing year by year, with diseases including hypertension and hyperlipidemia.

Cholesterol 52

Cholesterol Pharmacology Atherosclerosis Cancer 52

Heart 2023 Conference

MARCH 17, 2023

Atherosclerosis, also called " hardening of the arteries, " occurs when fat, cholesterol and other substances are deposited in the walls of the arteries. Atherosclerosis is a common disease. These deposits are called plaques. Over time, these plaques can narrow or completely block arteries and cause problems throughout the body.

Atherosclerosis 52

Atherosclerosis Exercise Plaque Cholesterol 52

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Cardiometabolic Health Congress

AUGUST 23, 2024

Newly included risk factors— untreated vision loss and high LDL cholesterol —underscore the critical role of these elements in maintaining cognitive health. The Cholesterol Connection Cholesterol’s recognition as a risk factor for dementia marks a pivotal advancement in understanding, preventing, and delaying cognitive decline.

Dementia 52

Dementia Cholesterol Risk Factors CME 52

Physiologically Speaking

JANUARY 5, 2024

Regarding blood lipids, there were no changes total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, or apolipoprotein A1 (ApoA1) or apolipoprotein-B (ApoB). LDL and ApoB — which play an obligate and causal role in the development of atherosclerosis — weren’t affected by exercise.

Plaque 119

Plaque Physiology Exercise Cholesterol 119

Circulation: Genomic and Precision Medicine

JULY 6, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 480-482, October 1, 2023.

Coronary Artery Disease 40

Coronary Artery Disease Cholesterol Atherosclerosis Circulation 40

Medical Xpress - Cardiology

FEBRUARY 26, 2025

Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC), leading to the formation of plaques.

Coronary Artery Disease 40

Coronary Artery Disease Heart Disease Plaque Atherosclerosis 40

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

The fundamental role of qualitative alterations of lipoproteins in the early development of atherosclerosis has been widely demonstrated. However, the corresponding studies are scarcer in the field of ischemic stroke, despite carotid arteriosclerosis progression underlies at least 20% of ischemic strokes.

Circulation 40

Circulation Stroke Strokes Atherosclerosis 40

Dr. Paddy Barrett

SEPTEMBER 19, 2023

I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. At the exact same time, cholesterol concentrations are also at their lowest. At the exact same time, cholesterol concentrations are also at their lowest. Let’s break this down.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Dr. Paddy Barrett

AUGUST 22, 2023

Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease. APO E is also centrally involved in cholesterol metabolism. Here’s how. What to do?

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Stroke Journal

NOVEMBER 9, 2023

Several mechanisms have been proposed to account for the association between HDAC9 and atherosclerosis including alterations in the inflammatory response and cholesterol efflux and endothelial-mesenchymal transition. Indirect data support such an approach in man.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40