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Atherosclerosis (ASVD) remains a leading driver of cardiovasculardisease (CVD), a global health challenge that claims millions of lives each year. Explore actionable, evidence-based strategies to combat traditional and emerging riskfactors, with a focus on precision approaches and primordial prevention.
Background Left ventricular (LV) mass is closely associated with atherosclerotic heart disease, but the mechanisms are not well defined. This study aimed to evaluate the riskfactors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovasculardisease.
Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional riskfactors, according to a new study.
In recent years, the incidence of cardiovasculardisease (CVD) has risen steadily, significantly impacting public health. Subclinical hypothyroidism (SCH) remains a controversial riskfactor for CVD.
And plaque in your coronary arteries is the result of exposure to riskfactors over time. These individuals then must have had one or more riskfactors for a long time prior to their heart attack. 2 You will not know you have heart disease by waiting for symptoms. The answer: RiskFactors.
Preeclampsia (PE) and type 1 diabetes (T1D) are significant riskfactors for cardiovasculardisease (CVD), but their combined effect on atherosclerosis progression has not been fully explored. This study aimed.
Do autoimmune diseases independently correlate with coronary atherosclerosis and atherosclerotic cardiovasculardisease (ASCVD) risk, and do traditional cardiovascularriskfactors modulate the risk?
Atherosclerosis (AS), a chronic inflammatory disease, remains a leading contributor to cardiovascular morbidity and mortality. Targeting this pathway offers a promising therapeutic strategy to reduce the burden of cardiovasculardiseases (CVD).
Findings from earlier research have established that insulin resistance (IR) is implicated in atherosclerosis progression, representing a noteworthy riskfactor for cardiovasculardisease (CVD). Recently, the.
Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a previously unrecognized, potent, age-related, and common riskfactor for atherosclerosis. The increased risk of developing hematologic malignancy does not, on its own, explain excess mortality in individuals with CHIP.
This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. The development of the Tina-quant Lipoprotein (a) Gen.2 J Clin Lipidol. 2024.03.001.
When it comes to cardiovasculardisease, two of the biggest riskfactors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. ApoB Atherosclerosis, by definition, is caused by the retention of an ApoB lipid particle in the artery wall. But only moderately.
The risk of atherosclerotic cardiovasculardisease (ASCVD) is approximately twofold higher for South Asian (SA) adults than for adults from other racial and ethnic groups. Type 2 diabetes mellitus (T2DM) is a highly prevalent riskfactor that likely contributes to this disparity.
Dysglycaemia is a known riskfactor for cardiovasculardisease and microcirculatory dysfunction is associated with an increased cardiovasculardiseaserisk. The aim of this study was to investigate the prevale.
Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovasculardisease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.
Background Hepatocyte growth factor (HGF) is a biomarker with potential for use in the diagnosis, treatment and prognostication of cardiovasculardisease (CVD). We used Poisson and linear mixed-effects regression models to estimate the association between HGF and ECC, adjusted for sociodemographic and CVD riskfactors.
Background:The role of immune suppressive microenvironment, promulgated by the presence of Myeloid Derived Suppressor Cells (MDSC) have been the major focus of research delineating the underlying mechanisms of cardiovasculardiseases (CVD). 3ng/day for 15 days).M-MDSCs
Here’s what you can expect at the biggest conference in cardiorenal metabolic health, the 19th Annual Cardiometabolic Congress (CMHC), DECODING THE CONSTELLATION of Cardiometabolic Health and RiskFactors. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
cobalt, copper, zinc) are associated with increased coronary artery calcification (CAC) and are comparable to traditional cardiovasculardiseaseriskfactors like smoking and diabetes, according to results from the Multi-Ethnic Study of Atherosclerosis (MESA) published in JACC.
Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging riskfactor for calcific aortic stenosis and a causal riskfactor for atherosclerotic cardiovasculardisease (ASCVD) in different ethnicities.
The prevalence of HF riskfactors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Overt cardiovasculardisease, which ranged from 2.1% (HF) to 13.6% (atrial fibrillation), was less common. were female, 25.6% were Black, 12.8%
Exercise prevents and reverses cardiovasculardisease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovasculardisease (CVD) prevention and reversal. Cardiac rehab works wonders.
“We are encouraged by the implementation of our AI cardiac solution at esteemed healthcare systems, along with the continued validation through real-world studies of its potential to promote early detection and preventive care of cardiovasculardisease,” said Erez Meltzer, Nanox Chief Executive Officer and Acting Chairman. “We
Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional riskfactors.
Updated with the latest research since the 2020 edition, this comprehensive report underscores the potential to prevent or significantly delay dementia by targeting modifiable riskfactors. The report now identifies 14 modifiable riskfactors for dementia.
Background:The association between left ventricular injury (LVI) detected by cardiac magnetic resonance imaging (CMR) and the risk of a subsequent ischemic stroke is unknown.Methods:We studied stroke-free participants in the Multi-Ethnic Study of Atherosclerosis study who underwent a steady-state free precession CMR at Exam 5 (2010-2012).
Circulation: Cardiovascular Imaging, Volume 17, Issue 2 , Page e015712, February 1, 2024. BACKGROUND:Coronary artery calcium computed tomography (CAC) is an important tool for identifying subclinical atherosclerosis and cardiovascularrisk stratification. Most patients in both groups were White (95.2% versus 38.1%;P<0.001);
The identification of a variant in theHDAC9gene as a riskfactor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023.
Introduction The independent and causal cardiovasculardiseaseriskfactor lipoprotein(a) (Lp(a)) is elevated in >1.5 billion individuals worldwide, but studies have prioritised European populations. Causal effects of increased Lp(a) with increased glycated haemoglobin were estimated for Europeans (p value =1.4
Immune-mediated inflammatory diseases (IMIDs) are recognised riskfactors for accelerated atherosclerotic cardiovasculardisease (CVD), particularly in younger individuals and women who lack traditional CVD riskfactors.
BackgroundElevated lowdensity lipoprotein cholesterol is a riskfactor for atherosclerotic cardiovasculardisease, including acute ischemic stroke (AIS), due to large and smallvessel disease.
Lipoprotein(a) (Lp[a]) can improve the accuracy of assessment of atherosclerotic cardiovasculardisease and the risk of aortic valve stenosis. Management of high levels encourages rigorous attention to correction of other riskfactors, such as blood pressure, smoking and low-density lipoprotein (LDL).
By understanding the significance of cardiovascular health, we can make informed choices and adopt lifestyle habits that promote a strong and resilient heart. Riskfactors for cardiovasculardisease Understanding the riskfactors for cardiovasculardisease is crucial for maintaining optimal cardiovascular health.
Background Lipoprotein(a) [Lp(a)] is an independent riskfactor for cardiovasculardisease due to its unique apo(a) component and its association with atherosclerosis and thrombogenesis.
We introduce a methodology and a framework used for preprocessing and harmonizing variables from multiple studies.RESULTS:We provide a real-case study and step-by-step guidance to demonstrate the practical utility of our repository and interactive web page.
Themed “Decoding the Constellation of Cardiometabolic Health and RiskFactors,” this year’s congress will tackle the growing health threat posed by cardiometabolic diseases, affecting 47 million people in the US. Shapiro, DO Back By Popular Demand!
Riskfactors such as smoking, chronic kidney disease, and aging can contribute to plaque formation. The gradual loss of elasticity in arterial walls and the presence of other riskfactors, such as high blood pressure and diabetes, contribute to the increased risk of cardiovasculardisease (CVD) observed in aging populations.
However Most people do not appreciate that being a carrier of APOE4 significantly increases the risk of cardiovasculardisease also. Share For those with defective LDL receptors, as seen in familial hyperlipidemia, APOB particles are not cleared effectively, and concentrations rise, causing atherosclerosis 4. 7 Ashiq, S.,
An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronary artery disease. But we must always remember that most genetic riskfactors are probabilistic rather than deterministic in terms of risk. Atherosclerosis. 2017 Jan;256:47-52.
See "Mechanisms of acute coronary syndromes related to atherosclerosis".) See "Prevention of cardiovasculardisease events in those with established disease (secondary prevention) or at very high risk".) Optical coherence tomography, due to its high resolution, may provide additional information [ 10,13 ].
Atherosclerosisa key driver of cardiovasculardisease (CVD)continues to be a significant global health issue. While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. Urbanization, increased sedentary lifestyles, and unhealthy diets have fueled this trend.
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovasculardisease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
Atherosclerotic cardiovasculardisease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovasculardisease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4
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