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Atherosclerosis Cardiovascular Disease Plaque 
Science Daily - Heart Disease
SEPTEMBER 18, 2024
The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis.
Science Daily - Heart Disease
NOVEMBER 13, 2024
Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.
Physiologically Speaking
JANUARY 5, 2024
Exercise prevents and reverses cardiovascular disease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovascular disease (CVD) prevention and reversal.
119 
Journal of Clinical Investigation - Cardiology
MARCH 1, 2024
Patients with chronic inflammatory disorders such as psoriasis have an increased risk of cardiovascular disease and elevated levels of LL37, a cathelicidin host defense peptide that has both antimicrobial and proinflammatory properties.
122 
Science Daily - Heart Disease
APRIL 30, 2024
Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.
Frontiers in Cardiovascular Medicine
MARCH 21, 2024
Introduction The progression of coronary atherosclerosis is an active and regulated process. The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.
Dr. Paddy Barrett
FEBRUARY 27, 2024
The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors. The answer.
112 
Frontiers in Cardiovascular Medicine
JANUARY 9, 2024
Atherosclerosis is a chronic inflammatory disease characterized by endothelial dysfunction and plaque formation. Under pro-inflammatory conditions, endothelial cells can undergo endothelial-to-mesenchymal transition (EndMT), contributing to atherosclerosis development.
Frontiers in Cardiovascular Medicine
MARCH 4, 2024
Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.
59 
DAIC
FEBRUARY 3, 2025
This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. 2022 Aug, 80 (9) 934946 Kronenberg F. J Clin Lipidol. 2024 May-Jun;18(3):e308-e319.
Circulation: Cardiovascular Imaging
JANUARY 11, 2024
BACKGROUND:Intensive lipid-lowering therapy may induce coronary atherosclerosis regression. Nevertheless, the factors underlying the effect of lipid-lowering therapy on disease regression remain poorly characterized. A decrease in the percentage of unstable core (fibro-fatty+necrotic plaque; from 14.1 [7.9–22.3] 10.6]; −6.6%;P<0.001)
40 
Circulation
NOVEMBER 11, 2024
Background:The role of immune suppressive microenvironment, promulgated by the presence of Myeloid Derived Suppressor Cells (MDSC) have been the major focus of research delineating the underlying mechanisms of cardiovascular diseases (CVD). 3ng/day for 15 days).M-MDSCs
Frontiers in Cardiovascular Medicine
JANUARY 24, 2024
Background Although atherosclerosis (AS) can affect multiple vascular beds, previous studies have focused on the analysis of single-site AS plaques. The plaques were then categorized into culprit plaques, non-culprit plaques, and non-event plaques.
45 
Dr. Smith's ECG Blog
NOVEMBER 15, 2023
MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. See "Mechanisms of acute coronary syndromes related to atherosclerosis".)
Stroke Journal
NOVEMBER 9, 2023
This article describes the pathway from gene discovery to novel therapeutic approaches that are now entering man.HDAC9expression is elevated in human atherosclerotic plaque, while in animal and cellular models, reducing HDAC9 (histone deacetylase 9) protein is associated with reduced disease.
40 Heart BMJ
MARCH 22, 2024
Immune-mediated inflammatory diseases (IMIDs) are recognised risk factors for accelerated atherosclerotic cardiovascular disease (CVD), particularly in younger individuals and women who lack traditional CVD risk factors.
40 
GEMMS
NOVEMBER 22, 2023
By understanding the significance of cardiovascular health, we can make informed choices and adopt lifestyle habits that promote a strong and resilient heart. Risk factors for cardiovascular disease Understanding the risk factors for cardiovascular disease is crucial for maintaining optimal cardiovascular health.
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
IntroductionAtherosclerosis, the hardening and narrowing of the arteries, occurs due to the buildup of plaque on the inner walls of the arteries which can result in reduced blood flow to the organs and tissues. Risk factors such as smoking, chronic kidney disease, and aging can contribute to plaque formation.
40 
Dr. Smith's ECG Blog
NOVEMBER 30, 2022
To prove there is no plaque rupture, you need to do intravascular ultrasound (IVUS). An angiogram is a "lumenogram;" most plaque is EXTRALUMINAL!! One of the most common is rupture of a non-obstructive plaque, with thrombus formation and OMI that spontaneously lyses and leaves a wide open artery. It can only be seen by IVUS.
52 
Cardiometabolic Health Congress
JANUARY 15, 2025
Atherosclerosisa key driver of cardiovascular disease (CVD)continues to be a significant global health issue. While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. Urbanization, increased sedentary lifestyles, and unhealthy diets have fueled this trend.
DAIC
MARCH 31, 2025
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
Science Daily - Heart Disease
SEPTEMBER 18, 2024
A team developed a nanoparticle technology that offers an effective solution to diagnose and treat atherosclerosis, in a non-invasive manner.
112 
DAIC
JANUARY 23, 2024
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.
DAIC
MARCH 31, 2025
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.
DAIC
JULY 18, 2024
The lead investigators for the study are Dr. Carlo De Cecco (Emory University, Atlanta) and Dr. Márton Kolossváry (Gottsegen National Cardiovascular Center, Budapest, Hungary). The ultimate goal is to positively impact cardiovascular health globally with a reduction in cardiovascular events."
105 
JAMA Cardiology
MARCH 4, 2025
This cohort study among participants in the Multi-Ethnic Study of Atherosclerosis (MESA) describes carotid artery plaque prevalence by age, sex, race, and ethnicity and investigates whether the impact of carotid plaque detection on relative risk of atherosclerotic cardiovascular disease declines with age and differs by sex.
83 
Cardiometabolic Health Congress
JUNE 20, 2024
The EAS 2024 Congress (May 26-29, 2024) has concluded, providing critical insights into atherosclerosis and related vascular disease. Giovanna Liuzzo (Italy) revealed that advancements in noninvasive imaging recently allow for direct visualization of coronary atherosclerotic plaques. Here are some notable highlights: Prof.
Frontiers in Cardiovascular Medicine
FEBRUARY 16, 2024
Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall. Here, we sought to investigate the role of autophagy activation during atherosclerosis regression.
Physiologically Speaking
FEBRUARY 23, 2024
However, a series of recent studies in mice and in humans reveals that protein may promote a cascade of events in the body that lead to cardiovascular disease. All of this is true, yet some observational studies (with all of their inherent flaws) have associated a high (animal) protein intake with cardiovascular disease risk.
111 
Physiologically Speaking
APRIL 10, 2024
Doubling this amount to 300 minutes of moderate-intensity or 150 minutes of vigorous-intensity activity per week would (if adhered to, of course) yield massive benefits for cardiovascular health. Remember that cardiovascular disease is the leading cause of death around the world. Something’s gotta give.
DAIC
OCTOBER 15, 2024
15, 2024 – Elucid has announced that four of the seven Medicare Administrative Contractors (MACs) will extend coverage for AI-enabled quantitative coronary plaque analysis, including its FDA-cleared PlaqueIQ image analysis software, beginning Nov. In the United States, one person dies every 33 seconds from cardiovascular disease.
52 
Dr. Paddy Barrett
JUNE 7, 2024
Heart disease is the presence of plaque or atherosclerosis in the coronary arteries. Over a long enough time horizon, pretty much everyone will develop a significant amount of plaque and have a heart attack. On average, they develop serious heart disease about 20 to 25 years later than everyone else 2.
Stroke Journal
JANUARY 30, 2025
Introduction:Stroke ranks as the second leading cause of death globally and the foremost in China, contributing significantly to the nations disease burden. Conclusions:In conclusion, our study highlights that intima-media thickening and plaques are more prevalent in adult carotid arteries, with a significantly higher prevalence in males.
Dr. Paddy Barrett
APRIL 5, 2024
Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
119 
Dr. Paddy Barrett
JANUARY 23, 2024
Cardiovascular disease is the leading cause of death worldwide. Over 80% of early heart disease is preventable. However, most adults will start to develop advanced plaque in their coronary arteries early in life. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.
106 
Stroke Journal
JANUARY 30, 2025
Objective:High calcium (Ca), low phosphate(P), and Ca-P product (CPP) levels are associated with cardiovascular disease and coronary artery atherosclerosis in patients with chronic kidney disease. individually. individually.
40 
Journal of the American Heart Association
FEBRUARY 23, 2024
BackgroundCarotid intima‐media thickness (cIMT) and carotid plaque are reliable indicators of cardiovascular disease risk, and research highlights that racial and ethnic minority individuals generally exhibit higher cIMT and carotid plaque than White individuals. Journal of the American Heart Association, Ahead of Print.
DAIC
OCTOBER 30, 2024
By adding AutoChamber AI to CAC scans and analyzing both coronary artery plaque calcification and cardiac chambers volume, HeartLung plans to introduce AI-CAC and AI-CVD which have the potential to advance preventive cardiology. We plan to add this AI to our lung cancer screening population who are high risk for cardiovascular events.
45 
Heart 2023 Conference
APRIL 20, 2022
Avocado consumption of at least two servings per week is linked to a lower risk of cardiovascular disease. Harvard University Heart Letter) A clinical polygenic risk score test for diseases ranging from atrial fibrillation (AFib) to breast cancer was piloted by scientists.
52 
Journal of the American Heart Association
JANUARY 12, 2024
BackgroundObesity is accompanied by dysregulated inflammation, which can contribute to vasculometabolic complications including metabolic syndrome and atherosclerosis. Recently, clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a risk factor for cardiovascular diseases.
40 
DAIC
MAY 16, 2024
PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.
Dr. Paddy Barrett
SEPTEMBER 5, 2023
Share Let’s first state our goal when we are in the business of ‘Heart Disease Prevention’: To delay the onset of coronary artery disease (atherosclerosis/plaque) that might rupture and cause a heart attack. And the less plaque you have, the lower the risk of a heart attack. But many people are.
52 
Dr. Paddy Barrett
MAY 31, 2024
The mistake most people make when it comes to heart disease is thinking that when someone has a heart attack that, the condition of ‘heart disease’ just appeared. But heart disease presents slowly. Atherosclerosis in the proximal segment of the vessel. The more plaque, the higher the risk.
Physiologically Speaking
MAY 17, 2024
Most of the evidence on the harms of extreme exercise is related to a biomarker of cardiovascular disease known as coronary artery calcification or CAC. Numerous reports in the last decade have found that lifetime endurance athletes have higher levels of coronary artery calcification and plaque compared to age-matched non-athletes.
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