Remove Atherosclerosis Remove Blood Pressure Remove Plaque
article thumbnail

Why Waiting Until Age 50 To Address Risk Factors For Heart Disease Is Too Late.

Dr. Paddy Barrett

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors. The answer.

article thumbnail

Beating the Odds: Inside the Tribe with a Near-Zero Rate of Heart Disease.

Dr. Paddy Barrett

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

article thumbnail

Lifestyle Risk Factors Predict Coronary Calcification among Male Endurance Athletes

Physiologically Speaking

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. Cross-sectional studies reveal that endurance athletes, particularly middle-aged and older men, often exhibit higher coronary artery calcium scores (CACS) and plaque prevalence compared to less-active individuals.

article thumbnail

Computed tomographic angiography measures of coronary plaque in clinical trials: opportunities and considerations to accelerate drug translation

Frontiers in Cardiovascular Medicine

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease.

Plaque 59
article thumbnail

How To Reverse Coronary Artery Disease With Lifestyle Measures

Dr. Paddy Barrett

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.

article thumbnail

The ratio of systolic and diastolic pressure is associated with carotid and femoral atherosclerosis

Frontiers in Cardiovascular Medicine

Background Although the impact of hypertension on carotid intima-media thickness (IMT) and plaques has been well established, its association with femoral IMT and plaques has not been extensively examined. Systolic and diastolic blood pressure (SBP and DBP) were used to define SDR. 1.49), plaques (OR = 1.36, 95%CI = 1.16–1.61),

article thumbnail

Why Measuring ApoB Is The Key To Preventing Heart Disease.

Dr. Paddy Barrett

When we say heart disease, what we really mean is plaque in the artery wall. This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. No atherosclerosis. No heart attacks.