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PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.
The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration. 14 One study of over 1,900 men found evidence that very short sleep duration predicts a higher burden of atherosclerosis in their coronary and femoral arteries.
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