This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
BackgroundAbdominal aortic calcification (AAC), an early indicator of abdominal aortic wall atherosclerosis, is a marker of subclinical atherosclerosis and a predictive factor for vascular-associated morbidity and mortality. These outcomes are driven by inflammatory processes.
This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. The development of the Tina-quant Lipoprotein (a) Gen.2 2022 Aug, 80 (9) 934946 Kronenberg F.
Background:Ischemic stroke can arise from various etiologies, such as cardioembolism, atherosclerosis, small vessel disease or cryptogenic. Accumulating evidence suggests that an imbalance of neuroprotective and neuroinflammatory cytokines may contribute to stroke outcomes. pg/ml) as compared to cardioembolic (35.6±6.5 p<0.01).Conclusions:Our
Background:Peripheral artery disease (PAD) is associated with high morbidity and mortality and is closely related to diabetes mellitus (DM) and atherosclerosis. These findings suggest that VTRNA2-1 promoter methylation status could serve as a valuable biomarker for predicting prognosis and guiding treatment strategies in PAD.
IntroductionIntracranial atherosclerosis‐related large vessel occlusion (ICAS‐LVO) is a common cause of failed mechanical thrombectomy (MT) in acute ischemic stroke (AIS) [1]. Treatment of ICAS‐LVO with rescue stenting and/or angioplasty has shown promising outcomes, but diagnosing ICAS‐LVO during MT can be challenging [2, 3].
Background:The association between left ventricular injury (LVI) detected by cardiac magnetic resonance imaging (CMR) and the risk of a subsequent ischemic stroke is unknown.Methods:We studied stroke-free participants in the Multi-Ethnic Study of Atherosclerosis study who underwent a steady-state free precession CMR at Exam 5 (2010-2012).
The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide.
The conference will equip health professionals with clinical strategies that promote comprehensive health and tools to harness new therapies to improve our collective health outcomes. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. Journal of the American Heart Association, Ahead of Print. In multivariate analysis, low CCDR (hazard ratio, 2.21 [95% CI, 0.99–4.92],P=0.04)
Keynote speaker and atherosclerosis expert Peter Libby, MD , captivated the audience with an update on his research into inflammation and atherosclerosis. He discussed therapeutic options not only for treating atherosclerosis but also for preventing cardiovascular disease. Ballantyne, MD , explored Lipoprotein(a).
While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. Stroke: Vascular and Interventional Neurology, Ahead of Print.
Inflammatory indicators such as neutrophil count and monocyte count potentially may predict patients’ outcomes and prognosis in ACS. Rate of MACE as composite outcome 30-days after PPCI as 24.7% (n=37). White blood cells count is an affordable and accessible way to assess the systemic immune response.
Dysregulation of the innate and adaptive immune system is accelerated by CKD and results in increased systemic inflammation, a heightened local vascular inflammatory response leading to accelerated atherosclerosis, and dysfunction of the cardiac and renal endothelium and microcirculation.
They have the biomarker of risk but no evidence of the disease , even later in life when you would expect them to have it. When there is a history of early events, then the likelihood of a member of that family with an elevated Lp(a) having premature coronary atherosclerosis is high. Atherosclerosis. 2017 Jan;256:47-52.
4] CT revealed no dissection but extensive coronary atherosclerosis. So even without the diagnostic ECGs, they had clinical evidence of refractory ischemia with biomarker (troponin) confirmation. In a study last year, 14.4% of patients diagnosed with STEMI had an initial troponin less than the 99 th percentile, including 23.4%
MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEART ATTACKS, STROKES AND CORONARY ARTERY DISEASE. THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE'S CLINT L.
5 Over my career as a cardiovascular surgeon, as well as an immunologist, I have witnessed how current treatments for ASCVD have led to considerable improvements in outcomes, yet many patients remain vulnerable to life-threatening cardiac events.1,6
This blog post explores the development of such partnerships and their potential to transform healthcare outcomes. Engaging individuals as active participants in their care plans can significantly enhance outcomes and improve overall quality of life. Key contributions: Advanced cardiac imaging (e.g.,
Background and Purpose:Chronic kidney disease (CKD) is associated with an increased risk of stroke and worse outcomes, yet it is often asymptomatic, with an estimated 90% of individuals unaware they have CKD until its later stages. Stroke, Volume 56, Issue Suppl_1 , Page A102-A102, February 1, 2025.
Though this effect has also been documented with statin therapy, monotherapy using PCSK9 inhibitors or ezetimibe have not been associated with similar reduction in biomarkers of inflammation. Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients. at 6 months compared to placebo. N Engl J Med. Epub 2023 Mar 4.
Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. The Latest Evidence on Atherosclerosis in Athletes The risk factor component is yet unexplored—how do risk factors other than training contribute to elevated CAC in endurance athletes?
With the holiday season approaching and fall in full swing, it’s the perfect time to reaffirm our commitment to delivering excellent care, improving patient outcomes, and making the most of every available resource. cardiometabolic health CME/CE conference: the 19th Annual CMHC.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content