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IV Thrombolysis + Thrombectomy vs. Thrombectomy Alone for Acute Ischemic Stroke

American College of Cardiology

What is the association of treatment with intravenous thrombolysis (IVT) plus thrombectomy versus thrombectomy alone and outcomes modification by the time from stroke symptom onset to treatment?

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Large-Bore Mechanical Thrombectomy vs. Catheter-Directed Thrombolysis for Treatment of Intermediate-Risk Pulmonary Embolism

American College of Cardiology

The goal of the trial was to compare the efficacy and safety of large-bore mechanical thrombectomy (LBMT) with catheter-directed thrombolysis (CDT) in the treatment of intermediate-high risk pulmonary embolism (PE).

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Multi-arm Optimization of Stroke Thrombolysis

American College of Cardiology

The goal of the MOST trial was to evaluate argatroban vs. eptifibatide vs. placebo among patients with acute ischemic stroke treated with intravenous thrombolytic therapy.

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Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48

American College of Cardiology

The ENGAGE AF-TIMI 48 trial sought to study the safety and efficacy of edoxaban, an oral direct factor Xa inhibitor, as compared with warfarin in the treatment of atrial fibrillation.

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Thrombolysis in Imaging-Eligible, Late-Window Patients to Assess the Efficacy and Safety of Tenecteplase

American College of Cardiology

The goal of the TIMELESS trial was to determine the efficacy and safety of tenecteplase administered between 4.5 and 24 hours after last known well time in patients with acute ischemic stroke and salvageable tissue on perfusion imaging.

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Retraction: Anterior Circulation Thrombectomy in Patients With Low National Institutes of Health Stroke Scale Score: Analysis of the National Inpatient Sample

Stroke: Vascular and Interventional Neurology

The following article, published online on August 23, 2023 inStroke: Vascular and Interventional Neurology, has been retracted by mutual agreement between the authors and the journal Editors. Specifically, the variables for endovascular therapy and intravenous thrombolysis were mistakenly switched.

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Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management

Stroke: Vascular and Interventional Neurology

To compile this narrative review, we conducted a systematic search of the PubMed database to identify relevant articles on the pathophysiological features and treatment of CRAO, including reviews, meta‐analyses, clinical studies, observational trials, and randomized trials. hours of symptom onset) results in better patient outcomes.

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