American College of Cardiology

OCTOBER 28, 2024

The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).

TAVR 63

TAVR Stenosis Aortic Aortic valve 63

American College of Cardiology

MARCH 19, 2025

Two studies analyzing data from the STS/ACC TVT Registry exploring out-of-hospital 30-day mortality after mitral transcatheter edge-to-edge repair (TEER) and one-year cause-specific mortality after TAVR were published in JACC: Cardiovascular Interventions on March 19.

TAVR 58

TAVR Bicuspid/Mitral Cardiovascular Interventions Hospital 58

American College of Cardiology

JULY 18, 2024

What are the national trends in utilization of leadless pacemaker implantation following transcatheter aortic valve replacement (TAVR) and its performance compared with transvenous pacemakers?

TAVR 58

TAVR Pacemaker Aortic valve Aortic 58

American College of Cardiology

OCTOBER 29, 2024

While the main PROTECTED TAVR trial found no significant differences in stroke rates when cerebral embolic protection (CEP) was used during TAVR compared with TAVR alone, a post hoc analysis of the trial presented during TCT 2024 and simultaneously published in JAMA Cardiology, suggests there may be potential benefits associated with CEP use based (..)

TAVR 53

TAVR Embolism Strokes Stroke 53

Cardiology Update

NOVEMBER 26, 2023

In light of the growing number of patients undergoing transcatheter aortic valve replacement (TAVR), there is an increasing demand for data regarding the management of failed TAVR procedures, including the possibility of a repeat TAVR intervention. vs. 3.5%, p=0.80) between the redo-TAVR and native-TAVR populations.

TAVR 52

TAVR Aortic valve Outcomes Aortic 52

American College of Cardiology

DECEMBER 10, 2024

A State-of-the-Art review published in JACC: Cardiovascular Interventions covers the epidemiology, clinical implications, risk factors and preventive strategies for new-onset conduction disturbances (CDs) and the need for permanent pacemaker implantation (PPI) after TAVR, which the authors note are a limitation of this therapy.

TAVR 65

TAVR Cardiovascular Interventions Pacemaker Risk Factors 65

American College of Cardiology

NOVEMBER 5, 2024

What are outcomes among patients younger than 65 years who received transcatheter aortic valve replacement (TAVR) using a balloon-expandable valve compared to patients aged 65-80 years?

TAVR 53

TAVR Aortic valve Outcomes Aortic 53

American College of Cardiology

MARCH 1, 2024

Despite decreasing rates of permanent pacemaker implantation (PPI) after TAVR, substantial site-level variation persists, suggesting the need for quality improvement initiatives like replicating best practices from high-performing sites and increased guideline-based education, according to a recent study published in JACC: Cardiovascular Interventions. (..)

TAVR 61

TAVR Pacemaker Best Practices Cardiovascular Interventions 61

American College of Cardiology

DECEMBER 4, 2024

Does measured or predicted prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR) affect all-cause mortality at 2 years?

TAVR 49

TAVR Aortic valve Outcomes Aortic 49

American College of Cardiology

AUGUST 5, 2024

What is the effect of the time interval between transcatheter aortic valve replacement (TAVR) and noncardiac surgery (NCS) (Δt) on the perioperative risk of major adverse events (MAEs)?

TAVR 49

TAVR Aortic valve Aortic Article 49

American College of Cardiology

MARCH 6, 2024

What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?

TAVR 60

TAVR Aortic Stenosis Aortic valve 60

American College of Cardiology

AUGUST 14, 2024

What is the relationship between diffusion-weighted magnetic resonance imaging (DW-MRI) total lesion number (TLN), individual lesion volume (ILV), and total lesion volume (TLV) with clinical stroke outcomes after transcatheter aortic valve replacement (TAVR)?

TAVR 53

TAVR Aortic valve Aortic Strokes 53

American College of Cardiology

APRIL 8, 2024

TAVR was found to bring no increased risks and was associated with substantially decreased rates of death or stroke at one year in low-risk patients, compared with surgical aortic valve replacement (SAVR), according to results from the DEDICATE-DZHK6 study presented during a Late-Breaking Clinical Trial session at ACC.24

TAVR 56

TAVR Aortic valve Aortic Strokes 56

American College of Cardiology

OCTOBER 28, 2024

Two separate late-breaking clinical trials – EARLY TAVR and EVOLVED – presented at TCT 2024 explore whether early aortic valve intervention improves outcomes in patients with asymptomatic aortic stenosis (AS).

TAVR 53

TAVR Aortic valve Aortic Stenosis 53

American College of Cardiology

NOVEMBER 6, 2024

In this week’s View, Dr. Eagle looks at the outcomes of balloon-expandable transcatheter aortic valve replacement (TAVR) in younger patients.

TAVR 53

TAVR Blood Pressure Aortic valve Aortic 53

American College of Cardiology

MAY 29, 2024

How do mortality and morbidity compare after valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) versus redo surgical aortic valve replacement (SAVR) for intervention for a failed bioprosthetic SAVR?

Aortic valve 49

Aortic valve TAVR Aortic Article 49

American College of Cardiology

AUGUST 21, 2024

Among patients undergoing transcatheter aortic valve replacement (TAVR) with a balloon-expandable valve (BEV), what are the 3-year clinical outcomes associated with a small (20 mm) compared to a larger (≥23 mm) device, and is there a relationship between the discharge echocardiographic (echo) mean gradient (MG) and measured or predicted thresholds (..)

TAVR 53

TAVR Aortic valve Outcomes Aortic 53

American College of Cardiology

OCTOBER 21, 2024

Patients with moderate or severe tricuspid regurgitation (TR) prior to undergoing TAVR or mitral transcatheter edge-to-edge repair (TEER), when compared to patients with no or mild TR, were associated with worse health status and clinical outcomes, according to a study published in JACC: Cardiovascular Interventions.

TAVR 53

TAVR Bicuspid/Mitral Outcomes Tricuspid 53

American College of Cardiology

NOVEMBER 6, 2024

What are the contemporary characteristics, trends, and outcomes of intravascular lithotripsy (IVL)-assisted transfemoral (TF) transcatheter aortic valve replacement (TAVR) in the United States?

TAVR 45

TAVR Aortic valve Outcomes Aortic 45

American College of Cardiology

APRIL 7, 2024

The supra-annular self-expanding Evolut PRO/PRO+/FX TAVR device was found to be superior for valve function and noninferior for clinical outcomes at one year compared to the balloon-expandable SAPIEN 3/3 Ultra TAVR device, according to the results of the SMART trial, presented during a Late-Breaking Clinical Trial Session at ACC.24

TAVR 49

TAVR Outcomes Article 49

American College of Cardiology

JANUARY 29, 2025

Self-expanding valves (SEVs) are associated with less prosthesis-patient mismatch (PPM) in East Asian patients with small aortic annuli (SAA) undergoing TAVR, compared with balloon-expandable valves (BEVs).

TAVR 49

TAVR Aortic Article 49

American College of Cardiology

FEBRUARY 8, 2024

Is there a relationship between site-level volumes and outcomes for transcatheter aortic valve replacement (TAVR) and mitral transcatheter edge-to-edge repair (MTEER)?

TAVR 49

TAVR Aortic valve Outcomes Hospital 49

American College of Cardiology

OCTOBER 29, 2024

In women with symptomatic, severe aortic stenosis (AS), TAVR with the balloon-expandable valve was superior to surgical aortic valve replacement in terms of the composite rate of death, stroke and rehospitalization at one-year follow-up, according to a pooled analysis of patient-level data from RHEIA and PARTNER 3 trials presented at TCT 2024.

TAVR 49

TAVR Aortic valve Aortic Stenosis 49

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Transcatheter aortic valve replacement (TAVR) is a relatively new treatment method for aortic stenosis (AS) and has been demonstrated to be suitable for patients with varying risk levels.

Aortic valve 64

Aortic valve Cardiac Rehabilitation Aortic TAVR 64

American College of Cardiology

JANUARY 6, 2025

Subclinical leaflet thrombosis (SLT) has raised concerns about the long-term durability and outcomes of transcatheter aortic valve replacement (TAVR). Clinical valve thrombosis (CVT) is a rare complication after TAVR with an incidence of 0.62.8%

Thrombosis 40

Thrombosis TAVR Aortic valve Aortic 40

American College of Cardiology

JUNE 13, 2024

What are the rates of a permanent pacemaker (PPM) implantation, the predictors of needing a PPM, and long-term clinical outcomes of the third-generation balloon-expandable SAPIEN 3 (S3) transcatheter heart valve (THV)?

Pacemaker 69

Pacemaker TAVR Outcomes Heart Valves 69

DAIC

MARCH 15, 2024

Widely recognized for pioneering innovative concepts and techniques in TAVR, Tang has set contemporary standards in the field. His research centers on the comprehensive management of patients post-TAVR, transcatheter mitral and tricuspid valve interventions, and advanced imaging techniques in structural heart disease.

TAVR 105

TAVR Academic Education Cardiovascular Surgery 105

American College of Cardiology

NOVEMBER 5, 2024

Patients younger than 65 years who received balloon-expandable valve TAVR for severe aortic stenosis during the low-surgical risk era were more likely to have comorbidities and exhibited higher rates of death and readmission at one year vs. patients aged 65 to 80 years, according to a study presented at TCT 2024 and simultaneously published in JAMA (..)

TAVR 45

TAVR Stenosis Aortic Outcomes 45

American College of Cardiology

MARCH 30, 2025

The goal of the ALIGN-AR trial was to evaluate the efficacy and safety of the JenaValve Trilogy transcatheter heart valve in patients with symptomatic, greater-than-moderate native aortic regurgitation who were deemed high risk for surgery by heart teams.

Aortic 63

Aortic TAVR Heart Valves Article 63

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

The presence of cardiac amyloidosis negatively affects the outcome of patients with aortic stenosis, these patients undergo transcatheter aortic valve replacement (TAVR) with increasing frequency and have a significantly higher overall mortality rate than patients with aortic stenosis alone.

Stenosis 69

Stenosis Aortic TAVR Aortic valve 69

American College of Cardiology

AUGUST 6, 2024

The following are key points to remember from a state-of-the-art guide to transcatheter aortic valve (TAV) design and systematic planning for a redo-TAV (TAV-in-TAV) procedure.

Aortic valve 66

Aortic valve TAVR Aortic Article 66

American College of Cardiology

OCTOBER 29, 2024

Risk-adjusted 30-day mortality after TAVR increased modestly from January 2019 to March 2022 in the U.S., according to an observational cohort study published in JAMA Cardiology. Exploratory analyses were unable to find any site-related, patient-related or process-related factors that explain these findings.

TAVR 40

TAVR Article 40

American College of Cardiology

SEPTEMBER 4, 2024

He then explores the prognostic ability of diffusion-weighted brain MRI lesions after TAVR. Eagle looks at the kidney and cardiovascular effectiveness of SGLT2 inhibitors versus GLP-1 receptor agonists in type 2 diabetes.

TAVR 40

TAVR Diabetes Article 40

American College of Cardiology

AUGUST 7, 2024

In this week’s View, Dr. Eagle looks at post-capillary pulmonary hypertension in heart failure and the revised European guideline definition. He then explores obesity in adolescents and its impact on our societal health.

Obesity 61

Obesity Pulmonary Hypertension TAVR 61

American College of Cardiology

FEBRUARY 17, 2024

Alain Cribier, MD, FACC, the man who pioneered the first transcatheter aortic valve replacement (TAVR), passed away on Feb. 16 at the age of 79.

Aortic valve 75

Aortic valve TAVR Aortic Article 75

American College of Cardiology

JUNE 18, 2024

In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.

Heart Failure 58

Heart Failure Stenosis Aortic TAVR 58

American College of Cardiology

FEBRUARY 18, 2025

The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.

Stenosis 61

Stenosis Aortic Aortic valve TAVR 61