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Multi-arm Optimization of Stroke Thrombolysis

American College of Cardiology

The goal of the MOST trial was to evaluate argatroban vs. eptifibatide vs. placebo among patients with acute ischemic stroke treated with intravenous thrombolytic therapy.

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IV Thrombolysis + Thrombectomy vs. Thrombectomy Alone for Acute Ischemic Stroke

American College of Cardiology

What is the association of treatment with intravenous thrombolysis (IVT) plus thrombectomy versus thrombectomy alone and outcomes modification by the time from stroke symptom onset to treatment?

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Retraction: Anterior Circulation Thrombectomy in Patients With Low National Institutes of Health Stroke Scale Score: Analysis of the National Inpatient Sample

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print. The following article, published online on August 23, 2023 inStroke: Vascular and Interventional Neurology, has been retracted by mutual agreement between the authors and the journal Editors. Stroke: Vascular and Interventional Neurology. 2023, e000998.[link]

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Intravenous Alteplase Versus Best Medical Therapy for Patients With Minor Stroke: A Systematic Review and Meta-Analysis

Stroke Journal

Stroke, Ahead of Print. Background:The efficacy of thrombolysis (IVT) in minor stroke (National Institutes of Health Stroke Scale score, 0–5) remains inconclusive. Results:A total of 20 high-quality studies, comprised of 13 397 patients with acute minor ischemic stroke, were included.

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Abstract TMP92: Dementia and Cognitive Impairment in Stroke: A Systematic Review and Meta-Analysis of Reperfusion Treatment Outcomes

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. Results:9 articles were included from 825 screened.

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Thrombolysis in Imaging-Eligible, Late-Window Patients to Assess the Efficacy and Safety of Tenecteplase

American College of Cardiology

and 24 hours after last known well time in patients with acute ischemic stroke and salvageable tissue on perfusion imaging. The goal of the TIMELESS trial was to determine the efficacy and safety of tenecteplase administered between 4.5

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Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print. Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that results in painless vision loss attributable to retinal infarction. Intravenous thrombolysis is a compelling therapeutic approach, with current limited data suggesting early intervention (4.5

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