Polygenic Risk in Families With Spontaneous SCAD
American College of Cardiology
JANUARY 29, 2024
What is the contribution of rare and common genetic variants to spontaneous coronary artery dissection (SCAD)?
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OAC or Aspirin Plus Ticagrelor Increases MACE Risk in SCAD Patients
American College of Cardiology
MARCH 25, 2025
Patients with spontaneous coronary artery dissection (SCAD) who are discharged on oral anticoagulation (OAC) or dual antiplatelet therapy (DAPT) that combines aspirin plus ticagrelor have a higher risk of major adverse cardiovascular events (MACE),
Is coronary dissection painful ?
Dr. S. Venkatesan MD
DECEMBER 2, 2023
Spontaneous coronary dissection vs Iatrogenic dissection SCAD is a rare , different entity , enjoys a popular space in the patho-physiology of CAD. An important therapeutic caution is PCI is contraindicated in SCAD except in critical locations such as left main. Is plaque fissure painful ?
Short-Chain Acyl-CoA Dehydrogenase as a Therapeutic Target for Cardiac Fibrosis
Journal of Cardiovascular Pharmacology
FEBRUARY 1, 2024
Short-chain acyl-CoA dehydrogenase (SCAD) negatively regulates pathological cardiac hypertrophy. The purpose of this study was to investigate the possible role of SCAD in cardiac fibrosis. Short-chain acyl-CoA dehydrogenase (SCAD) negatively regulates pathological cardiac hypertrophy.
Flavin adenine dinucleotide ameliorates pressure overload-induced heart failure by activating the short-chain acyl-CoA dehydrogenase
Journal of Cardiovascular Pharmacology
APRIL 7, 2025
In addition, FAD significantly increased the activity and expression of the short-chain acyl-CoA dehydrogenase (SCAD) enzyme and ATP content while reducing the content of free fatty acids and reactive oxygen species both in vitro and in vivo. FAD considerably inhibited tBHP-induced cardiomyocyte apoptosis. All rights reserved.
An athletic 30-something woman with acute substernal chest pressure
Dr. Smith's ECG Blog
JULY 31, 2018
Post by Smith, with short article by Angie Lobo ( [link] ), a third year intermal medicine resident at Abbott Northwestern Hospital Case A 30-something woman with no past history, who is very fit and athletic, presented with 1.5 What is Spontaneous Coronary Artery Dissection (SCAD)? hours of substernal chest pressure.
1 hour of CPR, then ECMO circulation, then successful defibrillation.
Dr. Smith's ECG Blog
MAY 19, 2020
Spontaneous coronary artery dissection (SCAD) should be considered as a cause of MINOCA. The ways to tell for certain include intravascular ultrasound (to look for extra-luminal plaque with rupture) or "optical coherence tomography," something I am entirely unfamiliar with. A list of conditions that can cause this is below.
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