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The article by Gwak et al provides a pivotal contribution to this field, illustrating that early surgical intervention for tricuspid regurgitation (TR) in patients with low to intermediate risk yields significant survival benefits. 2 3 Furthermore, persistent.
Pulmonary vein isolation (PVI) is the most effective treatment for rhythm control. In this article, we present our approach to fluoroless radiofrequency PVI using ICE and 3D electro-anatomical mapping. Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%.
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart disease characterized by the inability of all pulmonary veins to connect to the left atrium. Our previous bibliometric article sum.
Two articles and an accompanying editorial in Heart Rhythm , the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society , and the Pediatric & Congenital Electrophysiology Society , published by Elsevier , address the controversy and recommend shortening the blanking period. Lead author Jonathan M.
The following are key points to remember from a review comparing international clinical practice guideline recommendations for acute pulmonary embolism (PE):
In this week’s View, Dr. Eagle looks at post-capillary pulmonary hypertension in heart failure and the revised European guideline definition. He then explores obesity in adolescents and its impact on our societal health.
Pulmonary hypertension (PH) is a rare condition that reportedly affects 1% of the global population, although estimates vary on the basis of age group and setting.
What are the short-term outcomes for patients with native or surgically repaired right ventricular outflow tract (RVOT) undergoing transcatheter pulmonary valve replacement (TPVR) with a self-expanding valve?
What is the real-world lesion durability of pulmonary vein isolation (PVI) with pulsed-field ablation (PFA) among patients with clinically indicated redo procedures?
In the article byTakajoetal, Mortality Patterns in Pediatric Pulmonary Vein Stenosis: Insights Into Right Ventricular Systolic Pressure Associations, which published online on January 17, 2025 (J Am Heart Assoc.2025;2025;14:e037908. Journal of the American Heart Association, Ahead of Print. 2025;2025;14:e037908. DOI:10.1161/JAHA.124.035037)
Pulmonary hypertension is a rare disease, associated with a significant deterioration in quality of life, usually not curable and with an ominous prognosis. We present the case of a patient diagnosed with precapillary component pulmonary hypertension, with the finding of an arteriovenous fistula at the peripheral level.
In this week’s View, Dr. Eagle looks at excess apolipoprotein-B and cardiovascular risk, then examines a recent meta-analysis on treating pulmonary arterial hypertension. Finally, Dr. Eagle shares some thoughts on a SMART-C collaborative meta-analysis of sodium-glucose cotransporter-2 inhibitors and major adverse cardiovascular outcomes.
The goal of the A DUE trial was to compare the safety and efficacy of macitentan/tadalafil combination therapy versus macitentan and tadalafil monotherapies in patients with pulmonary arterial hypertension (PAH).
What is the safety and utility of invasive implanted hemodynamic monitoring (IHM) using the CardioMEMS™ HF System in pediatric patients with heart failure (HF) and pulmonary hypertension (PH)?
Pulmonary embolism (PE) continues to challenge clinicians with its complex presentation and potential for rapid deterioration. As the third leading cause of cardiovascular mortality in the U.S.
What is the impact on prognosis of the 2022 ESC/ERS pulmonary hypertension (PH) guidelines on the new redefined hemodynamic threshold for the diagnosis of precapillary PH?
In this article, we’ll explore some of the leading fellowship specialties, what they entail, and the career paths they open for doctors committed to continuous learning and professional growth. Pulmonology A fellowship in pulmonology focuses on respiratory health, a field that has grown in importance in recent years.
™s Cordellaâ„¢ Pulmonary Artery Sensor System for the treatment of patients with NYHA class III heart failure (HF). Food and Drug Administration (FDA) on June 24 gave premarket approval for Endotronix, Inc.’s
William Boden and Bradley Maron discuss the latest advancements in managing pulmonary hypertension caused by left heart disease. In this interview, Drs.
In this week’s View, Dr. Eagle looks at the durability of pulmonary vein isolation using pulsed-field ablation, then examines genetic penetrance of dilated cardiomyopathy in genotype-positive relatives.
Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that eventually leads to heart failure (HF) and subsequent fatality if left untreated. Right ventricular (RV) function has proven prognostic values in patients with a variety of heart diseases including PAH.
The goal of the SHAM-PVI trial was to compare the clinical efficacy of cryoballoon pulmonary vein isolation (PVI) to a sham procedure in the treatment of symptomatic atrial fibrillation (AF).
However, whether AMOTL2 is linked to pulmonary arterial hypertension (PAH) has not been addressed. Overexpression of AMOTL2 also led to a noteworthy decrease in vascular wall thickness, pulmonary artery area, and collagen deposition in rats with PAH. This work aimed to investigate the potential role of AMOTL2 in PAH.
Acute pulmonary embolism (PE) is a frequently encountered diagnosis in both the emergency department (ED) and among hospitalized patients, with increasing incidence throughout the U.S.
Compared with a sham procedure, pulmonary vein isolation resulted in a statistically significant and clinically important decrease in atrial fibrillation (AFib) burden at six months, according to results from the SHAM-PVI trial presented at ESC Congress 2024 in London and simultaneously published in JAMA.
The goal of the trial was to compare the efficacy and safety of large-bore mechanical thrombectomy (LBMT) with catheter-directed thrombolysis (CDT) in the treatment of intermediate-high risk pulmonary embolism (PE).
Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance, imposing overload on the right ventricle (RV) and imbalance of redox state. PAH induction was implemented by a single dose of MCT (60 mg/kg i.p.). Treatment with SFN (2.5 mg/kg/day i.p.)
Pulmonary embolism (PE) mortality has increased over the past decade and racial and geographic disparities persist. Black women and men have an approximately two-fold higher age-adjusted mortality rate compared with White women and men, respectively.
Initial macitentan and tadalafil combination therapy in pulmonary arterial hypertension (PAH) patients with or without cardiac comorbidities. 6MWD, 6-min walk distance; NT-proBNP, N-terminal pro-brain natriuretic peptide; PVR, pulmonary vascular resistance; WHO FC, World Health Organization functional class.
Abstract Introduction Carina breakthrough (CB) at the right pulmonary vein (RPV) can occur after circumferential pulmonary vein isolation (PVI) due to epicardial bridging or transient tissue edema. High-power short-duration (HPSD) ablation may increase the incidence of RPV CB.
The perspectives and priorities of people living with chronic obstructive pulmonary disease (COPD) should be integrated into the development process of new therapies for COPD, according to a new commentary. The article is published in the Annals of the American Thoracic Society.
Abstract: Pulmonary artery hypertension (PAH) is characterized by pulmonary arterial endothelial cells (PAECs) dysfunction and pulmonary artery smooth muscle cells (PASMCs) activation. For decades, the therapies for PAH based on stem cells have been shown to be effective.
The decision of whether to perform a large anatomic resection for a lung mass that is not definitely malignant comes often forward in the everyday practice of the thoracic surgeon. The general characteristics.
Extended anticoagulant therapy with a reduced-dose of apixaban was noninferior to extended therapy with a full-dose of apixaban in preventing recurrent venous thromboembolism (VTE) in patients with active cancer and proximal deep-vein thrombosis or pulmonary embolism, based on findings from the API-CAT trial presented at ACC.25
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