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In patients with obesity and heart failure with preservedejectionfraction (HFpEF), weekly treatment with tirzepatide over approximately two years reduced the risk of worsening heart failure events, based on findings from the SUMMIT trial.
Heart failure with preservedejectionfraction (HFpEF) and atrial fibrillation (AF) are comorbid conditions that are increasingly prevalent and have a high socioeconomic burden. This article discusses their shared pathophysiology, focusing on the triad of hypertension, obesity, and aging.We
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preservedejectionfraction (HFpEF). Overall, 60.9% of patients had BMI ≥30 kg/m 2.
Abstract Introduction Emerging evidence suggests a beneficial effect of higher heart rates in some patients with heart failure with preservedejectionfraction (HFpEF). This article is protected by copyright. All rights reserved.
BMI, body mass index; CI, confidence interval; LVEF, left ventricular ejectionfraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heart failure with a mildly reduced or preservedejectionfraction (HFmrEF/HFpEF) and is associated with worse outcomes.
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