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ST-elevation myocardialinfarction (STEMI) is a critical cardiovascular emergency characterized by acute coronary artery occlusion and subsequent myocardial injury. The current standard of care is primary percutaneous coronary intervention (PPCI), which aims to rapidly restore epicardial blood flow.
The goal of the CLEAR SYNERGY OASIS 9 trial was to determine the long-term cardiovascular (CV) effects of colchicine following percutaneous coronary intervention (PCI) for ST-segment elevation or large non–ST-segment elevation myocardialinfarction (STEMI or NSTEMI, respectively).
Hemoglobin (Hb) threshold for red cell transfusion in myocardialinfarction (MI) with anemia has been a matter of debate. Previous randomized trials have not consistently shown a benefit of liberal transfusion strategy.
Significant complications associated with this condition include ischemic stroke, heart failure, myocardialinfarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF. In the U.S.,
From a total of 452 records, 29 articles were eligible for full-text review, whereof, data from 14 articles were systematically collated. The mean age ranged between 56 and 76 and 5873 years for depressed vs. non-depressed individuals respectively. Poor ventricular function (26.16.8
The goal of the CLEAR SYNERGY (OASIS 9) spironolactone trial was to determine the potential cardiovascular (CV) benefit of spironolactone following percutaneous coronary intervention (PCI) for ST-segment or large non–ST-segment elevation myocardialinfarction (STEMI or NSTEMI, respectively) regardless of post-MI left ventricular ejection fraction (..)
Cardio-cerebral infarction (CCI) is a rare clinical syndrome characterized by the simultaneous or sequential occurrence of acute myocardialinfarction (AMI) and acute ischemic stroke (AIS).
The goal of the REDUCE-AMI trial was to evaluate the potential benefit of beta-blockade following acute myocardialinfarction (AMI) in patients with preserved left ventricular ejection fraction (LVEF) in the modern era of coronary revascularization and medical therapy.
The MULTISTARS AMI (MULTivessel Immediate versus STAged RevaScularization in Acute MyocardialInfarction) trial compared immediate versus delayed percutaneous coronary intervention (PCI) of nonculprit lesions in patients with ST-segment elevation myocardialinfarction (STEMI) who underwent successful primary PCI of the culprit lesion.
Both the COMPLETE and PRAMI trial findings supported the benefits of complete revascularization over culprit-only percutaneous coronary intervention (PCI) in patients presenting with myocardialinfarction (MI) and multivessel coronary artery disease.
Background Hyperglycemia, characterized by elevated blood glucose levels, is frequently observed in patients with acute coronary syndrome, including ST-elevation myocardialinfarction (STEMI). Methods We conducted a comprehensive search for articles on PubMed and Embase using search strategies which yielded 4,061 articles.
The goal of the PACMAN-AMI trial was to demonstrate the efficacy of early administration of alirocumab on plaque characteristics among patients undergoing percutaneous coronary intervention (PCI) for an acute myocardialinfarction (AMI).
The goal of the TALOS-AMI trial was to assess whether de-escalating dual antiplatelet therapy (DAPT) with clopidogrel rather than ticagrelor 1 month after percutaneous coronary intervention (PCI) for an acute myocardialinfarction (AMI) would be a noninferior strategy.
The goal of the EMPACT-MI trial was to determine whether adding the sodium-glucose cotransporter-2 (SGLT2) inhibitor empagliflozin to the treatment of acute myocardialinfarction (AMI) affects future mortality or heart failure (HF) in at-risk patients.
Current guidelines regarding beta-blocker use after myocardialinfarction (MI) recommend against continuation to improve outcomes after 1 year, in the absence of reduced left ventricular ejection fraction (LVEF; <50%) or other primary indications for therapy.
The goal of the ECLS-SHOCK trial was to evaluate extracorporeal life support (ECLS) compared with control among patients with acute myocardialinfarction (MI) and cardiogenic shock.
Objectives This study aimed to perform a meta-analysis of the short-term impact of ischaemic postconditioning (IPoC) on myocardial injury in ST elevation myocardialinfarction (STEMI) using surrogate cardiac biomarkers. Methods Eligible studies were identified using several article databases.
The goal of the ABYSS trial was to evaluate beta-blocker interruption compared with beta-blocker continuation after an uncomplicated myocardialinfarction (MI).
The goal of the SENIOR-RITA trial was to evaluate routine invasive therapy compared with conservative therapy among older patients with non–ST-elevation myocardialinfarction (NSTEMI).
Myocardial remodeling is characterized by gradual heart enlargement, cardiac dysfunction, and extraordinary molecular changes. Cardiac remodeling after myocardialinfarction is almost inevitable, which is the leading cause of heart failure. Autophagy has a protective effect on myocardial remodeling improvement.
Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardialinfarction was suboptimal in many patients and gave an ‘illusion of reperfusion’.
Chronic inflammation plays a role in the pathogenesis of cardiovascular diseases, including atherosclerosis, pericarditis, stroke, and myocardialinfarction (MI).
The International Registry of MitraClip in Acute Mitral Regurgitation following Acute MyocardialInfarction (IREMMI). Methods and results The International Registry of MitraClip in Acute Mitral Regurgitation following Acute MyocardialInfarction (IREMMI) includes 187 patients with severe MR post-MI managed with TEER.
The article by Aslanger, Smith et al that is featured above in today’s post has just been published. The above-cited newly published article by Aslanger, Smith et al provides further support to the growing body of literature of why we should compel ourselves to do so. P.S.: Our September 3, 2020 post features Dr.
Impella and venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients with acute myocardialinfarction-related cardiogenic shock (AMICS). Methods and results This nationwide observational cohort study describes all AMICS patients treated with Impella (ABIOMED, Danvers, MA, USA) and/or VA-ECMO in 2020–2021.
Among individuals without significant cardiovascular morbidity younger than 50 years, the use of cannabis is linked to adverse cardiovascular events, including a sixfold higher risk of a myocardialinfarction (MI), fourfold increase risk of ischemic stroke.
See these 2 articles Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardialinfarction: A post-hoc analysis of the AVOID study Author links open overlay panel [link] 1 Background We sought to determine if an association exists between prehospital chest pain severity and markers of myocardial injury.
Nature Reviews Cardiology, Published online: 19 June 2024; doi:10.1038/s41569-024-01055-5 In this Tools of the Trade article, Berkeley and Thomson describe the use of a minimally invasive strategy to standardize the induction of myocardialinfarction in mice.
What is the impact of procedural myocardialinfarction (pMI) and spontaneous myocardialinfarction (spMI) across different levels of troponin elevation on mortality among patients undergoing percutaneous coronary intervention (PCI)?
Rivaroxaban was found to be as effective and safe as warfarin in resolving post myocardialinfarction (MI) left ventricular (LV) thrombus at three months, according to a Late-Breaking Clinical Trial presented at ACC.25 25 in Chicago.
What is the impact of complete revascularization versus culprit-only revascularization on outcomes in older patients with ST-segment elevation myocardialinfarction (STEMI) and non–ST-segment elevation myocardialinfarction (NSTEMI)?
HYPERACUTE T-WAVES ARE EASILY RECOGNIZED BY THE QUEEN OF HEARTS HYPERACUTE T-WAVES DO NOT EVOLVE INTO ST ELEVATION -- THIS IS A MYTH Pendell and I are about to submit an article on ECG findings in total 100% LAD Occlusion (LAD OMI). Hyperacute T Wave in the Early Diagnosis of Acute MyocardialInfarction. 2023;82:194–202.
Is early cardiac magnetic resonance (CMR) prior to an invasive coronary angiogram (ICA) in patients with suspected non–ST-segment elevation myocardialinfarction (NSTEMI) useful?
The following are key points to remember from a JACC Focus Seminar, which presents an in-depth, contemporary understanding of the pathophysiology, clinical consequences, and management of right ventricular (RV) myocardialinfarction (MI).
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