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Despite proven benefits in reducing morbidity and mortality, many heartfailure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). Original article: Man JP et al. ESC HeartFailure 2024; 11 : 560–569. This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors.
It can be associated with reduced quality of life and complications such as heartfailure and stroke. In this article, we present our approach to fluoroless radiofrequency PVI using ICE and 3D electro-anatomical mapping. Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%.
In patients with obesity and heartfailure with preserved ejection fraction (HFpEF), weekly treatment with tirzepatide over approximately two years reduced the risk of worsening heartfailure events, based on findings from the SUMMIT trial.
In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity. For a complete list of additional authors and their disclosures, please see the full article in the New England Journal of Medicine.
This study found that treatment with sodium–glucose cotransporter 2 (SGLT2) inhibitors in patients with heartfailure and reduced ejection fractions (HFrEF) was associated with lower skeletal muscle pathology. Muscle biopsies were collected from patients treated with SGLT2 inhibitors (>12 months) and compared to untreated controls.
Iron deficiency (ID) is a common comorbidity among patients with heartfailure (HF), and it is associated with reduced exercise tolerance and quality of life and serves as a marker of increased risk of hospitalizations and mortality.
Heartfailure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are comorbid conditions that are increasingly prevalent and have a high socioeconomic burden. This article discusses their shared pathophysiology, focusing on the triad of hypertension, obesity, and aging.We
In this episode, Andrea Price, MS, AACC hosts Jae Patton, MSN, CRNP, AACC and Sarah Godfrey, MD, MPH to share insights for ensuring quality of life when time is short: tools for the end-stage heartfailure care.
Abstract Introduction In hypertrophic cardiomyopathy (HCM), atrial fibrillation (AF) has historically been regarded to have a deleterious impact on clinical course, strongly associated with progressive heartfailure (HF) symptoms. Therefore, we evaluated the impact of AF on QoL utilizing patient reported outcome measures (PROMs).
TAVR in heartfailure. ABSTRACT Patients with severe aortic stenosis (AS) may develop heartfailure (HF), the presence of which has traditionally been deemed as a final stage in AS progression with poor outcomes. The prognostic covariates and optimal timing of TAVR in patients with less than severe AS remain unclear.
The disease can cause a variety of symptoms, including heartfailure, arrhythmias, peripheral embolism, dysautonomia, angina with normal coronary arteries, and others. The disease can cause a variety of symptoms, including heartfailure, arrhythmias, peripheral embolism, dysautonomia, angina with normal coronary arteries, and others.
Abstract Introduction Emerging evidence suggests a beneficial effect of higher heart rates in some patients with heartfailure with preserved ejection fraction (HFpEF). This article is protected by copyright. All rights reserved.
Exercise training in patients with advanced heartfailure and left ventricular assist device (Ex-VAD) trial. Aims Small studies and observations suggested that exercise training may improve peak oxygen consumption (peakVO 2 ) in patients with advanced heartfailure and left ventricular assist device (LVAD).
This 2023 Cochrane review of 60 randomized trials in 8728 heartfailure patients, confirms the benefits of participation in exercise-based cardiac rehabilitation (ExCR), including reduced risk of hospitalization and a clinically meaningful improvement in health-related quality of life.
Identifying new targeted therapeutic approaches has become a priority of biomedical research to improve patient outcomes and quality of life. In this article, we first describe how ERK signaling contributes to preserving cardiovascular health.
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heartfailure (HF) with preserved ejection fraction (HFpEF). Obesity was associated with more first and recurrent heartfailure events. Overall, 60.9% of patients had BMI ≥30 kg/m 2.
Clinicians working with older patients have witnessed firsthand how polypharmacy can complicate both their care and diminish quality of life. Drugs That May Cause or Exacerbate HeartFailure: A Scientific Statement from the American Heart Association. had one or more severe potential drug-drug interaction.1
Abstract Continuous flow left ventricular assist devices (CF-LVADs) have been shown to reduce mortality and morbidity in patients with advanced heartfailure with reduced ejection fraction. Several questions, however, remain regarding the efficacy of ICD and CRT following CF-LVAD.
Abstract Right-sided heartfailure and tricuspid regurgitation are common and strongly associated with poor quality of life and an increased risk of heartfailure hospitalizations and death. This article is protected by copyright. All rights reserved.
This article will explore how AI-driven diagnostics are reshaping cardiovascular medicine and how can healthcare leaders can leverage these innovations to improve patient care and control costs. Unplanned cardiac hospitalizations can be very expensive, with studies showing the cost of an index heartfailure hospitalization averaging $13,000.
ABSTRACT Aim Chronic obstructive pulmonary disease (COPD) is common in heartfailure with a mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and is associated with worse outcomes. The primary outcome was a composite of cardiovascular death or worsening heartfailure. 0.93]; COPD: HR 0.82 [95% CI 0.62–1.10];
So, if living longer, at a higher quality of life with preserved cognitive capacity is a priority, then exercise has to be on your list. I have discussed this at length in a previous article here. 13 Statins and risks of dementia among patients with heartfailure: a population-based retrospective cohort study in Hong Kong.
CI, confidence interval; COPD, chronic obstructive pulmonary disease; HF, heartfailure; HR, hazard ratio; TIA, transient ischaemic attack. The treatment effect of HIC versus UC on the primary endpoint, 180-day death or heartfailure (HF) rehospitalization, was compared by NCC number and by each individual comorbidity.
Clinically meaningful improvements in Atrial Fibrillation Effect on QualiTy-of-life scores were seen at 3 months and were sustained to 12 months postablation, and accompanied with reduction of Class I/III AAD use and DCCV. Central Illustration.
Findings from the TAVR UNLOAD trial found preemptive TAVR was not superior to clinical aortic stenosis surveillance (CASS) for the hierarchical occurrence of all-cause death, disabling stroke, disease-related hospitalizations and heartfailure equivalents, and change in quality of life among patients with moderate aortic stenosis (AS) and heartfailure (..)
5+) support is effective in facilitating heart recovery, overall survival, and quality of life. Methods and results This single-centre retrospective study examined midterm (180 days) outcomes of patients with CS supported by Impella 5+ who achieved heart recovery. The average duration of Impella support was 10.5 ± 8 days.
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