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New Treatment in Pipeline for Patients with Hypertrophic Cardiomyopathy

DAIC

In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity. All participants were receiving background medical therapy and had reduced exercise capacity.

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Impact of cardiac rehabilitation on pre- and post-operative transcatheter aortic valve replacement prognoses

Frontiers in Cardiovascular Medicine

TAVR outcomes, with respect to post-surgical functional capacity and quality of life, have also been found to be improved, especially when combined with cardiac rehabilitation (CR).

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Supervised exercise training in patients with advanced heart failure and left ventricular assist device: A multicentre randomized controlled trial (Ex?VAD trial)

European Journal of Heart Failure

Exercise training in patients with advanced heart failure and left ventricular assist device (Ex-VAD) trial. Aims Small studies and observations suggested that exercise training may improve peak oxygen consumption (peakVO 2 ) in patients with advanced heart failure and left ventricular assist device (LVAD). m (95% CI 16.9,

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A potential research target for cardiac rehabilitation: brain-derived neurotrophic factor

Frontiers in Cardiovascular Medicine

Cardiovascular diseases pose a major threat to human life, functional activity, and quality of life. There is a consensus on the benefits of cardiac rehabilitation in improving patients’ quality of life, enhancing functional activity, and reducing mortality.

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Exercise?based cardiac rehabilitation for adults with heart failure – 2023 Cochrane systematic review and meta?analysis

European Journal of Heart Failure

This 2023 Cochrane review of 60 randomized trials in 8728 heart failure patients, confirms the benefits of participation in exercise-based cardiac rehabilitation (ExCR), including reduced risk of hospitalization and a clinically meaningful improvement in health-related quality of life.

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Focus on Heart Failure | Ironclad: The Treatment of Iron Deficiency in Heart Failure

American College of Cardiology

Iron deficiency (ID) is a common comorbidity among patients with heart failure (HF), and it is associated with reduced exercise tolerance and quality of life and serves as a marker of increased risk of hospitalizations and mortality.

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New SEQUOIA-HCM Analysis Sheds Further Light on Benefits of Aficamten in Patients With oHCM

American College of Cardiology

Treatment with aficamten in patients with obstructive hypertrophic cardiomyopathy (oHCM) was associated with broad clinical efficacy across multiple outcome domains, including rapid and sustained decreases in outflow gradients, meaningful improvements in functional class and quality of life, enhanced exercise capacity, and significant reductions in (..)