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Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy

Frontiers in Cardiovascular Medicine

ZGCD not only significantly reduces blood pressure, but also enhances cardiac function while producing fewer adverse effects. In light of this, a thorough evaluation of the benefits and safety of Zhigancao decoction (ZGCD) was conducted in this study using RevMan and Stata.

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NT-proBNP and Troponin I in Cardiac Function

American College of Cardiology

How do N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-CTnI) predict long-term changes in cardiac structure and function in older adults?

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Management of acute decompensated valvular heart disease

European Journal of Heart Failure

In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock. After screening a total of 2234 articles, 76 published between 1994 and 2023 were included in subsequent analysis.

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Engineered exosomes: a potential therapeutic strategy for septic cardiomyopathy

Frontiers in Cardiovascular Medicine

This article examines the strategies for using engineered exosomes to protect cardiac function and treat septic cardiomyopathy. The article highlights the ability of exosomes to deliver small molecules, proteins, and drugs, summarizing several RNA molecules, proteins, and drugs beneficial for treating septic cardiomyopathy.

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Coagulation Factor XI Level and Cardiac Events and Function

American College of Cardiology

Are plasma factor XI levels associated with cardiovascular events and cardiac function in humans?

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Top Stories: Mitochondrial origin of inherited cardiac arrhythmias

HeartRhythm

Mitochondria control cardiac function by regulating adenosine triphosphate synthesis, reactive oxygen species (ROS) generation, intracellular calcium (Ca2+), and the cellular redox state. Yet, their role in the pathophysiology of arrhythmias remains massively underappreciated.

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Canonical Transient Receptor Potential (TRPC) Channels in Cardiovascular Pathology and their Modulators

Journal of Cardiovascular Pharmacology

Ion channels play a crucial role in various aspects of cardiac function, such as regulating rhythm and contractility. Cell function is substantially influenced by the concentration of free cytosolic calcium (Ca2+) and the voltage across the plasma membrane.