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Cholesterol’s Star Role in Dementia Prevention: New Insights from the 2024 Lancet Dementia Report 

Cardiometabolic Health Congress

Newly included risk factors— untreated vision loss and high LDL cholesterol —underscore the critical role of these elements in maintaining cognitive health. The Cholesterol Connection Cholesterol’s recognition as a risk factor for dementia marks a pivotal advancement in understanding, preventing, and delaying cognitive decline.

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American Heart Month Puts Spotlight on Cardiovascular Disease and Stroke Statistics

DAIC

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. percent Compound Annual Growth Rate (CAGR).

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Why You Need To Measure apoB To Assess Your Cardiovascular Risk

Dr. Paddy Barrett

The fundamental characteristic of atherosclerosis is when a cholesterol particle becomes trapped in the artery wall. It is the inflammatory response to this particle retention that causes the formation of atherosclerosis 1. Lipoprotein particles entering the subintimal space causing atherosclerosis. TG = Triglycerides.

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HDAC9 Inhibition as a Novel Treatment for Stroke

Stroke Journal

This article describes the pathway from gene discovery to novel therapeutic approaches that are now entering man.HDAC9expression is elevated in human atherosclerotic plaque, while in animal and cellular models, reducing HDAC9 (histone deacetylase 9) protein is associated with reduced disease. Indirect data support such an approach in man.

Stroke 40
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Do Statins Cause Dementia?

Dr. Paddy Barrett

Share If you do not read any further, you will have come away with the main takeaway of this article. I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. At the exact same time, cholesterol concentrations are also at their lowest.

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APOE4 & Cardiovascular Risk

Dr. Paddy Barrett

A subsequent article will focus on the risk of late-onset dementia for those carriers of APOE4. Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease.

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The Advantages Of A CT Coronary Angiogram

Dr. Paddy Barrett

This article is part 2 of a series on cardiac CT. If you have not yet read it, I suggest doing so before reading the remainder of this article. I've included the article here. A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent. And it matters.