The most popular Heart Sisters article in 2024
Heart Sisters
DECEMBER 29, 2024
Was this particular article the most popular of 2024 because my HEART SISTERS readers aren't getting clear jargon-free, patient-friendly answers from their doctors?
Article Related Topics 
Call for a consensual definition of dyslipidemia in coronary angiography trials
Frontiers in Cardiovascular Medicine
FEBRUARY 4, 2025
We listed definitions and their references in the 258 articles the research found. Out of the 258 articles retrieved in the search, 52 studies (20%) provided a definition of dyslipidemia, and 20 (8%) mentioned the source. A systematic search of coronary angiography studies focusing on dyslipidemia was conducted.
What I learned from writing my most-read ‘Heart Sisters’ articles in 2023
Heart Sisters
DECEMBER 31, 2023
The most-popular HEART SISTERS posts from 2023 were all over the map - from 'Struggle Care' to sweating, hanging up that iconic Red Dress, or cardiac arrest on the toilet!
Cardiac Arrest 
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Deadline Extended for Submissions to the AI in Cardiovascular Health Collection!
International Journal of Cardiovascular Sciences
MARCH 27, 2025
The International Journal of Cardiovascular Sciences has extended the deadline for article submissions to the special issue on Artificial Intelligence in Cardiovascular Health until August 30, 2025 ! Publications in this collection will continue until December 2025. More information: revistaijcs@cardiol.br
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Deadline Extended: Special Collection on Artificial Intelligence in Cardiovascular Health
International Journal of Cardiovascular Sciences
DECEMBER 3, 2024
We would like to inform you that the deadline for submitting articles for the special collection on Artificial Intelligence in Cardiovascular Health has been extended to March 1, 2024. We look forward to your contribution to enrich this special edition!
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Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation
Frontiers in Cardiovascular Medicine
MARCH 25, 2025
This review article explores the intricate mechanisms by which uremic toxins accelerate vascular inflammation. These toxins play a pivotal role in mediating vascular inflammation, a key contributor to the high cardiovascular morbidity and mortality observed in CKD patients.
Gene-related metabolic dysfunction may be driving heart arrhythmia
Science Daily - Heart Disease
AUGUST 12, 2024
Patients with a common heart arrhythmia called Atrial Fibrillation could benefit from future treatments that target inefficiencies in heart cell metabolism, according to a new article.
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Enhancing microcirculation in STEMI patients: can intracoronary thrombolysis combined with thrombus aspiration provide an optimal strategy?
Frontiers in Cardiovascular Medicine
MARCH 28, 2025
This article explores the potential role of intracoronary thrombolysis, in conjunction with thrombus aspiration, in improving microcirculatory perfusion during PCI for STEMI patients. The current standard of care is primary percutaneous coronary intervention (PPCI), which aims to rapidly restore epicardial blood flow.
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Clinical significance of NT-proBNP as a predictive biomarker of depressive symptoms in cardiac patients
Frontiers in Cardiovascular Medicine
APRIL 1, 2025
From a total of 452 records, 29 articles were eligible for full-text review, whereof, data from 14 articles were systematically collated.
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Lactate metabolism and lactylation in cardiovascular disease: novel mechanisms and therapeutic targets
Frontiers in Cardiovascular Medicine
NOVEMBER 26, 2024
In light of the swift advancements in this domain, this review article is dedicated to examining lactylation in cardiovascular disease and potential drug targets for regulating lactylation, with the aim of enhancing comprehension of this intricate field.
MicroRNAs as regulators of cardiac dysfunction in sepsis: pathogenesis and diagnostic potential
Frontiers in Cardiovascular Medicine
FEBRUARY 17, 2025
Duplicate articles, those without abstracts or full texts, and review/meta-analyses or non-English articles were excluded. After initial filtering by the database search engine, Excel software was used to further screen references. miRNAs play diverse roles in SIMD.
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'Paving the way' for improved treatment of premature aging disease
Science Daily - Heart Disease
OCTOBER 18, 2024
A new article could spur the development of new and improved treatments for Hutchinson-Gilford progeria syndrome (HGPS), a rare genetic disorder with no known cure that causes accelerated aging in children.
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Call for Assistant Editor
International Journal of Cardiovascular Sciences
APRIL 8, 2025
This is an excellent opportunity for early-career individuals in the cardiovascular health field who wish to develop editorial skills and contribute to the advancement of science in this area, as well as engage in the journals outreach activities.
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Cardiac defibrillation in humans
HeartRhythm
FEBRUARY 27, 2025
Because neither is alive to tell their story, I was asked to write the article, adding information on the early days of the implantable transvenous cardioverter. This article highlights the first attempts at ventricular defibrillation and the development of the implantable defibrillator and the implantable transvenous cardioverter.
'A hearty debate' concludes plant-based meat alternatives are healthier for your heart than meat
Science Daily - Heart Disease
JUNE 25, 2024
A review article of the available studies directly comparing the impact of plant-based and animal-based meats consistently suggests that the plant-based alternatives improve cardiovascular risk factors.
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Functional assessment of coronary artery disease in patients with severe aortic stenosis: a review
Heart BMJ
FEBRUARY 26, 2025
The purpose of this review article is to provide a summary of the current data regarding the functional assessment of CAD in patients with severe AS and highlight the current best practice in this evolving area.
Dual-task training and cognitive performance in individuals with coronary artery disease and/or heart failure: a systematic review
Frontiers in Cardiovascular Medicine
MARCH 5, 2025
The certainty of evidence was assessed using Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.ResultsA total of 2,098 articles were retrieved, and 21 articles were selected for full reading.
An approach to fluoroless radiofrequency atrial fibrillation ablation
Frontiers in Cardiovascular Medicine
JANUARY 21, 2025
In this article, we present our approach to fluoroless radiofrequency PVI using ICE and 3D electro-anatomical mapping. Additional advantages include providing electrophysiology lab personnel with a lead-free working environment and avoiding radiation exposure for both patients and physicians.
AI Chatbots Show Promise as Patient Information Source for Glaucoma
HCPLive
APRIL 24, 2024
Article intelligence chatbots, including ChatGPT and Bard, varied in accuracy, comprehensiveness, and readability on glaucoma questions adapted from patient brochures.
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Motivational interviewing intervention for the management of hypertension: a meta-analysis
Frontiers in Cardiovascular Medicine
JANUARY 19, 2025
The search was restricted to articles published in English and Chinese languages. software was used for meta-analysis.ResultsA total of 16 RCTs were included. The meta-analysis findings demonstrate that motivational interviewing could reduce both systolic pressure [MD=3.26, 95% CI (5.16, 1.36), P 0.05).ConclusionsMotivational
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Ezetimibe Plus Statins Equals Better Outcomes
CardiacWire
MARCH 26, 2025
Digging through decades of data from PubMed, Embase, and ClinicalTrials.gov, researchers pooled all relevant articles published through June 2024 (108k patients) and found that a combination lipid-lowering therapy (LLT) of statins plus ezetimibe led to significantly better CV outcomes compared to statin monotherapy.
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Atrial fibrillation: A review
Science Daily - Heart Disease
DECEMBER 16, 2024
In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality.
Foods with low Nutri-Scores associated with an increased risk of cardiovascular diseases, study finds
Science Daily - Stroke
SEPTEMBER 12, 2024
In a new article, reesearchers report an increased risk of cardiovascular diseases associated with the consumption of foods that rank less favorably on the Nutri-Score scale (new 2024 version) within the European cohort EPIC.
Reassessing the role of tricuspid valve surgery in the modern era
Heart BMJ
MARCH 13, 2025
The article by Gwak et al provides a pivotal contribution to this field, illustrating that early surgical intervention for tricuspid regurgitation (TR) in patients with low to intermediate risk yields significant survival benefits.
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Cardio-cerebral infarction: a narrative review of pathophysiology, treatment challenges, and prognostic implications
Frontiers in Cardiovascular Medicine
MARCH 25, 2025
Furthermore, this article aimed to enhance clinicians' understanding of CCI, provide evidence-based recommendations for patient care, and outline directions for future research. Ultimately, by refining diagnostic and therapeutic strategies, we aimed to reduce CCI-related mortality and improve long-term prognoses for affected patients.
A Win
Dr. Malcolm Kendrick
OCTOBER 21, 2024
1 It is a much longer thing, which lays out in more detail, what was wrong with the article, and may contain sections such as: ‘Mr Calman allowed the experts who had helped him to have “a very significant”, and “undue”, influence over the editorial process and the terms of the article. ‘ Boy, do these things take ages.
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Novel device therapies in heart failure: focus on patient selection
Frontiers in Cardiovascular Medicine
FEBRUARY 24, 2025
In light of these potential limitations, this review article proposes categorizing HF patients into four distinct phenoprofiles based on their tolerance to GDMT and candidacy for HRT. Considering these HF phenoprofiles may guide treatment decisions regarding the selection and use of novel device-based HF therapies.
The function of miRNAs in the immune system's inflammatory reaction to heart failure
Frontiers in Cardiovascular Medicine
DECEMBER 1, 2024
This article reviews the role of miRNA in the inflammatory response in heart failure. Heart failure is associated with long-term and insufficient inhibition of inflammatory response.
Diagnostic accuracy of artificial intelligence models in detecting congenital heart disease in the second-trimester fetus through prenatal cardiac screening: a systematic review and meta-analysis
Frontiers in Cardiovascular Medicine
FEBRUARY 23, 2025
Articles were retrieved based on PRISMA Flow 2020 and inclusion and exclusion criteria. Artificial intelligence (AI)-powered ultrasound provides a potential solution to improve the diagnostic accuracy of fetal CHD screening.MethodsA literature search was conducted across seven databases for systematic review.
Insulin resistance/hyperinsulinemia: an important cardiovascular risk factor that has long been underestimated
Frontiers in Cardiovascular Medicine
MARCH 12, 2024
This article aims to stimulate the scientific community towards IR/Hyperins as relevant cardiovascular risk factor, since it is still neglected.
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Physiology Friday #255: Strength Training for Endurance, Optimal HIIT Protocols, Omega-3s + a Big Announcement!
Physiologically Speaking
JANUARY 31, 2025
I plan to contribute articles and more to Marathon Handbook on a regular basis. The benefits derived from progression runs is also the topic of this article by Matt Fitzgerald, another training expert. I’ve just finished reading a half-dozen recent articles on processed foods. Thanks so much. I won’t be far away.
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Study shows how high blood sugar increases risk of thrombosis
Medical Xpress - Cardiology
NOVEMBER 6, 2024
The findings, reported in an article published in the Journal of Thrombosis and Haemostasis, can contribute to the development of strategies to prevent cardiovascular dysfunction in diabetics.
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Young man with Gunshot wound to right chest with hemorrhagic shock, but bullet path not near heart
Dr. Smith's ECG Blog
MARCH 7, 2024
I’ve attached an article and an abstract (that article is in Japanese unfortunately … ) that do document that you CAN however on occasion find AIVR in otherwise healthy children — and I suppose that IS what we have here.
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A tonic for tumultuous times: an interview with “Reasons To Be Cheerful”
Heart Sisters
NOVEMBER 10, 2024
In this article from "Reasons To Be Cheerful", the Global Alliance for Women’s Health warns that it’s simply too expensive to ignore half of humankind.
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Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
Journal of Cardiothoracic Surgery
FEBRUARY 4, 2025
Full text research articles discussing clinical or cost-effectiveness aspects of Inspiris Resilia bioprosthesis published in English were included in this analysis. Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve.
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Exploring research trends and hotspots on PCSK9 inhibitor studies: a bibliometric and visual analysis spanning 2007 to 2023
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
The current study aims to delineate research hotspots and anticipate future trends on PCSK9 inhibitors employing bibliometric analysis.MethodsA systematic search was conducted in the Web of Science Core Collection (WoSCC) to identify scholarly articles and reviews pertaining to PCSK9 inhibitors, yielding 1,812 documents.
Mapping Memories: Enhancing Retrospective Data with the Life History Calendar
European Journal of Cardiovascular Nursing
MARCH 6, 2025
This article offers a comprehensive overview of the LHC approach, highlighting its flexible design and diverse administration methods. The Life History Calendar (LHC) has emerged as a solution to these limitations by incorporating visual prompts and contextual cues to enhance recall and improve data quality.
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Effective CRISPR modulation of complex non-coding RNA loci
Nature Reviews - Cardiology
JANUARY 13, 2025
Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01117-2 In this Tools of the Trade article, Francesca Vacante and Andrew Baker describe a CRISPR-based approach to target the regulatory regions of non-coding RNAs.
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Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and atherosclerotic cardiovascular disease: a meta-analysis of randomized controlled trials
Frontiers in Cardiovascular Medicine
FEBRUARY 12, 2025
Two reviewers independently screened articles and extracted data. The quality of the included studies was assessed using the Cochrane Risk Assessment Tool 2.0. Meta-analysis was performed using RevMan 5.4 software.ResultsOf the 2,698 publications screened, 42 studies were included, and the related trials involved 4,654 Chinese patients.
Identification of a novel NKX2-5 variant in a young Ecuadorian patient with atrioventricular block and bradycardia: a case report
Frontiers in Cardiovascular Medicine
APRIL 3, 2025
This article describes the case report of a young Ecuadorian child diagnosed with AV block and bradycardia. Notably, the transcription factor NKX2-5 plays a crucial role in heart development and function, and mutations in this gene have been linked to bradycardia and AV block. Furthermore, by performing NGS, a missense variant, p.(Tyr274Ser)
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Shorten the Blanking Period After Atrial Fibrillation Ablation, Experts Say
DAIC
APRIL 18, 2024
Two articles and an accompanying editorial in Heart Rhythm , the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society , and the Pediatric & Congenital Electrophysiology Society , published by Elsevier , address the controversy and recommend shortening the blanking period. Lead author Jonathan M.
ACC Celebrates Heart Month 2025
American College of Cardiology
FEBRUARY 3, 2025
Start off the month by reading the February issue of Cardiology magazine, including articles on health equity, life expectancy disparities in the U.S., Join the ACC in celebrating Heart Month! polypharmacy for older adults and more.
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Traction force microscopy of cardiomyocytes
Nature Reviews - Cardiology
JANUARY 20, 2025
Nature Reviews Cardiology, Published online: 21 January 2025; doi:10.1038/s41569-025-01123-4 In this Tools of the Trade article, Lyall discusses the use of traction force microscopy to assess the contractile function of individual cardiomyocytes.
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67 Surgical Management of Intracerebral Hemorrhage: New Light on the Horizon?
Stroke Journal
JANUARY 6, 2025
In this critique article, we will discuss the main findings of these trials, their implications and future perspectives.
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