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Abstract TMP111: Perivascular von Willebrand factor (VWF) promotes irregular remodeling of leptomeningeal collaterals in response to sustained increased luminal flow.

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATMP111-ATMP111, February 1, 2025. Introduction:VWF is an endothelial protein with known roles in hemostasis and thrombosis. We previously demonstrated abnormal deposition of VWF in themurallayer of leptomeningeal collateral arterioles (LMCs) during flow-induced outward remodeling.