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Thrombin in Pregnancy and Preeclampsia: Expression, Localization and Vasoactivity in Brain and Microvessels from Rats

Journal of Cardiovascular Pharmacology

Thrombin is a coagulation factor increased in pregnancy and further increased in preeclampsia (PE), a hypertensive disorder. We characterized thrombin expression and vasoactivity in brain cerebral parenchymal arterioles (PAs) in rat models of pregnancy and PE. Thrombin is also expressed in brain and may have a nonhemostatic role.

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Abstract 017: Rapid Progression Of Microhemorrhage In A Patient With An Atypical CADASIL Variant

Stroke: Vascular and Interventional Neurology

The first panel evaluates 10 genes for variants which are associated with hereditary forms of cerebral small vessel disease, encompassing those conditions in which small arteries, arterioles, venules, and capillaries of the brain are compromised.