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Long-term transcranial ultrasound stimulation regulates neuroinflammation to ameliorate post-myocardial infarction cardiac arrhythmia and remodeling

HeartRhythm

Sympathetic overactivation and neuroinflammation in the paraventricular nucleus (PVN) are crucial factors in post-myocardial infarction (MI) cardiac remodeling and ventricular arrhythmias (VAs). Meanwhile, the cGAS-STING pathway has shown potential to ameliorate neuroinflammatory response.

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Low-intensity focused ultrasound modulation of the paraventricular nucleus to prevent myocardial infarction-induced ventricular arrhythmia

HeartRhythm

Our previous study showed that light-emitting diode (LED) modulation of hypothalamic paraventricular nucleus (PVN), which is the control center of the sympathetic nervous system, might attenuate neuroinflammation in PVN and prevent ventricular arrhythmias (VAs) after myocardial infarction (MI).

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Protective Effects of Low‐Intensity Pulsed Ultrasound on Cardiac Electrophysiological Function in a Rat Model of Ischemic Cardiomyopathy

Journal of the American Heart Association

BackgroundIschemic cardiomyopathy (ICM) is the end stage of ischemic heart disease, in which ventricular remodeling contributes to a fatal ventricular arrhythmia, worsens heart function and unfavorable outcomes, and is related to persistent chronic inflammation. Vagotomy was applied to suppress the cholinergic antiinflammatory pathway.

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Torsade in a patient with left bundle branch block: is there a long QT? (And: Left Bundle Pacing).

Dr. Smith's ECG Blog

Bedside cardiac ultrasound showed moderately decreased LV function. (And of course Ken's comments at the bottom) An elderly obese woman with cardiomyopathy, Left bundle branch block, and chronic hypercapnea presented hypoxic with altered mental status. She was intubated. CT of the chest showed no pulmonary embolism but bibasilar infiltrates.

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PO-05-185 ELECTROMECHANICAL WAVE IMAGING FOR ARRHYTHMOGENIC MITRAL VALVE DISEASE CHARACTERIZATION IN THE CLINIC

HeartRhythm

Due to the tethering of the LV tissue, 43% of MV Prolapse (MVP) subjects will develop ventricular arrhythmias that often remain undiagnosed or uncorrelated with MV disease presence. Electromechanical Wave Imaging (EWI) is a high frame rate ultrasound modality that noninvasively maps the electromechanical (EM) wave in all cardiac chambers.

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Young Man with Very Fast Regular Wide Complex Tachycardia

Dr. Smith's ECG Blog

He arrived in the ED and had an immediate bedside cardiac ultrasound while this ECG was being recorded. The bedside ultrasound (video not available) reportedly showed only a slightly reduced LV function. The patient was given 6mg, then 12 mg, of adenosine, without a change in the rhythm. Here is the ECG: What do you think?

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Biosense Webster Study Supports Low and Zero Fluoroscopy Workflow as Safe, Effective Alternative to Conventional Catheter Ablation

DAIC

a global leader in cardiac arrhythmia treatment and part of Johnson & Johnson MedTechi , revealed findings from a company-funded study of real-world data. The updated workflow indicates that direct imaging guidance, such as ultrasound, may be used as an alternative to fluoroscopy. "As

Ablation 105