The British Journal of Cardiology

OCTOBER 8, 2024

Patients with such variants can present with a wide spectrum of arrhythmias but sudden death is generally considered rare. Pathogenic genetic variants in the HCN4 (hyperpolarisation-activated and cyclic nucleotide-gated channel) gene can cause sinus node dysfunction, disrupting the function of the pacemaker region of the heart.

Sudden Cardiac Death 52

Sudden Cardiac Death Pacemaker Arrhythmia Outcomes 52

HeartRhythm

OCTOBER 9, 2024

Triggers for and/or the occurrence of sudden cardiac death (SCD), and cardiac arrhythmias seem to follow such daily patterns. These clocks are found in virtually all cells in the body, including cardiomyocytes.

Arrhythmia 40

Arrhythmia Sudden Cardiac Death Electrophysiology 40

HeartRhythm

JANUARY 26, 2024

Sympathetic nervous system hyperactivity plays a major role in the pathogenesis of ventricular arrhythmias following myocardial infarction (MI).1,2 1,2 The stellate ganglia are an important nexus point for sympathetic innervation to the heart.3

Arrhythmia 80

Arrhythmia Sudden Cardiac Death Myocardial Infarction Tachycardia 80

Circulation

AUGUST 4, 2024

Despite early evidence of an antiarrhythmic role of n-3 PUFA in the prevention of sudden cardiac death and postoperative and persistent atrial fibrillation (AF), subsequent well-designed randomized trials have largely not shown an antiarrhythmic benefit.

Sudden Cardiac Death 81

Sudden Cardiac Death Arrhythmia Atrial Fibrillation Circulation 81

HeartRhythm

APRIL 30, 2024

The relationship between sarcopenia and ventricular arrhythmia (VA) is unknown. Sarcopenia is a geriatric syndrome featuring muscle mass, strength, and function loss. It is strongly associated with faster progression of cardiovascular diseases and an increased risk of mortality.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Cardiovascular Disease 40

HeartRhythm

APRIL 30, 2024

Mitral annular disjunction (MAD) increases the risk of ventricular arrhythmias (VAs) and sudden cardiac death in patients with mitral valve prolapse (MVP), but its arrhythmogenic basis is unknown.

Bicuspid/Mitral 40

Bicuspid/Mitral Sudden Cardiac Death Arrhythmia 40

Journal of Cardiovascular Pharmacology

MAY 7, 2024

Concerns regarding the risk of cardiac arrhythmia and death have been raised, yet the burden of HCQ and CQ-related cardiac toxicities remains unclear. Concerns regarding the risk of cardiac arrhythmia and death have been raised, yet the burden of HCQ and CQ-related cardiac toxicities remains unclear.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Article Outcomes 40

Medical Xpress - Cardiology

JUNE 28, 2024

A heart attack is a life-threatening condition, with patients remaining at risk of premature death long after the actual attack—50% to 60% of patients die subsequently as a result of sudden cardiac death, triggered by cardiac arrhythmia.

Sudden Cardiac Death 82

Sudden Cardiac Death Pacemaker Heart Attack Heart attacks 82

HeartRhythm

NOVEMBER 13, 2023

Arrhythmogenic role of epicardial adipose tissue (EAT) in atrial arrhythmias is well established, but its effect on ventricular arrhythmias has been significantly less investigated. Since ventricular arrhythmias are thought to cause 75% to 80% of cases of sudden cardiac death, this is not a trivial issue.

Arrhythmia 40

Arrhythmia Sudden Cardiac Death Research 40

HeartRhythm

APRIL 30, 2024

Examination of previously reported predictors of lethal ventricular arrhythmias or sudden cardiac death (VA/SCD) by ECG in Brugada syndrome (BrS) is a manual measurement and lacks objectivity.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Electrocardiogram 40

HeartRhythm

APRIL 30, 2024

Inherited arrhythmias (IAs) account for a significant proportion of sudden cardiac death (SCD) in young patients without overt heart disease. Recent studies have suggested that substantial proportion of IAs is much prevalent in East Asian people.

Pediatrics 40

Pediatrics Sudden Cardiac Death Arrhythmia Heart Disease 40

Science Daily - Heart Disease

JANUARY 15, 2024

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study.

Sudden Cardiac Death 102

Sudden Cardiac Death Arrhythmia 102

HeartRhythm

AUGUST 27, 2024

Sleep-disordered breathing (SDB) increases the risk of cardiac arrhythmias and sudden cardiac death.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia 40

Medical Xpress - Cardiology

JANUARY 14, 2024

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study in Heart Rhythm.

Sudden Cardiac Death 56

Sudden Cardiac Death Heart Rhythm Arrhythmia 56

HeartRhythm

JANUARY 13, 2024

The increased risk of arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation has been a prominent safety pharmacology concern for the last 30 years.

Sudden Cardiac Death 71

Sudden Cardiac Death Pharmacology Arrhythmia 71

Circulation

NOVEMBER 11, 2024

Background:In patients with type 2 diabetes (T2D), hyperglycemia and glycemic variability lead to prolongation and greater heterogeneity of ventricular repolarization, manifested on the electrocardiogram through an increase in QT, QTc, TpeakTend (TpTe) intervals and the TpTe/QT ratio, increasing the risk of potentially malignant arrhythmias.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Laboratory Electrocardiogram 40

Heart BMJ

FEBRUARY 12, 2024

This approach has delivered a novel perspective on arrhythmia management, with important distinctions from other policymakers’ recommendations.

Arrhythmia 40

Arrhythmia Sudden Cardiac Death Atrial Fibrillation Heart Rhythm 40

HeartRhythm

APRIL 30, 2024

Repolarization heterogeneities are known to significantly influence susceptibility to arrhythmias, a leading cause of sudden cardiac death.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia 40

HeartRhythm

APRIL 30, 2024

Wearable cardioverter-defibrillator (WCD) is an alternative option for the prevention of sudden cardiac death in patients at high risk for malignant ventricular arrhythmias.

Defibrillator 40

Defibrillator Sudden Cardiac Death Arrhythmia 40

Open Heart

MARCH 8, 2024

The wearable cardioverter defibrillator (WCD) is becoming a more and more widely used instrument for the prevention of sudden cardiac death of patients either with a secondary prevention implantable cardioverter defibrillator indication or with a transient high risk of sudden cardiac death.

Sudden Cardiac Death 52

Sudden Cardiac Death Defibrillator Atrial Fibrillation Arrhythmia 52

Journal of Cardiovascular Electrophysiology

FEBRUARY 8, 2024

Patients with Brugada syndrome who are asymptomatic and have no ventricular tachycardia/ventricular fibrillation inducibility by programmed electrical stimulation are at extremely low risk of experiencing late life-threatening arrhythmias. Methods Patients with BrS ( n  = 523; mean age, 51 ± 13 years; male, n  = 497) were enrolled.

Arrhythmia 40

Arrhythmia Sudden Cardiac Death Tachycardia Risk Factors 40

HeartRhythm

JANUARY 17, 2024

Sudden cardiac death in children and young adults is a relatively rare but tragic event whose pathophysiology is unknown at the molecular level. Evidence indicates that the main cardiac sodium channel (NaV1.5) and the strong inward rectifier potassium channel (Kir2.1)

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia 40

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death.

Cardiomyopathy 72

Cardiomyopathy Sudden Cardiac Death Article Heart Failure 72

HeartRhythm

JANUARY 29, 2024

The main result of the CAST (Cardiac Arrhythmia Suppression Trial), shown in Figure 1,1 was completely unexpected: The suppression of ventricular ectopy with antiarrhythmic drugs (AADs) was associated with an increased incidence of lethal ventricular arrhythmias in patients with post–myocardial infarction (post-MI) at high risk of sudden cardiac death (..)

Sudden Cardiac Death 40

Sudden Cardiac Death Myocardial Infarction Arrhythmia 40

HeartRhythm

APRIL 30, 2024

Long QT syndrome is most commonly an inherited condition associated with a risk of sudden cardiac death. It is recognized that LQTS in the fetus may present as sinus bradycardia (SB), functional 2:1 atrioventricular block and ventricular arrhythmias (VA).

Sudden Cardiac Death 40

Sudden Cardiac Death Bradycardia Arrhythmia 40

HeartRhythm

APRIL 30, 2024

Studies of sudden cardiac death (SCD) risk intend to specify substrate for fatal arrhythmia rescuable by defibrillator but presume cardiac cause. The Postmortem Systematic Investigation of SCD (POST SCD) study showed nearly half of presumed SCDs (pSCDs) are due to non-arrhythmic causes (e.g.,

Sudden Cardiac Death 40

Sudden Cardiac Death Defibrillator Arrhythmia Strokes 40

Frontiers in Cardiovascular Medicine

MARCH 13, 2024

The issue is relevant since some arrhythmias are associated to sudden cardiac death occurring in young patients, and the overall risk does not cease during the early postpartum period. Arrhythmias were documented in all the patients during the first cardiological assessment.

Cardiomyopathy 59

Cardiomyopathy Sudden Cardiac Death Outpatient Arrhythmia 59

Frontiers in Cardiovascular Medicine

OCTOBER 7, 2024

Non-caseating granulomatous infiltration of the myocardium is the hallmark of cardiac sarcoidosis (CS). CS manifests clinically as conduction disturbance, ventricular arrhythmia, sudden cardiac death and/or heart failure with reduced ejection fraction.

Sudden Cardiac Death 52

Sudden Cardiac Death Arrhythmia Heart Failure 52

HeartRhythm

APRIL 30, 2024

There is an unmet need for better risk stratification for sudden cardiac death in the era of primary prevention ICD therapy. Scar burden on LGE-CMR imaging may be a risk marker for ventricular arrhythmia post-myocardial infarction (MI).

Sudden Cardiac Death 40

Sudden Cardiac Death Risk Factors Myocardial Infarction Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Sudden cardiac death (SCD) is one of the most important causes of mortality in the world. The Purkinje network has been implicated in MI-related arrhythmogenesis, but the precise mechanisms by which they may sustain electrical activity in the scar tissue and arrhythmias remain unknown.

Myocardial Infarction 40

Myocardial Infarction Sudden Cardiac Death Electrophysiology Risk Factors 40

HeartRhythm

APRIL 30, 2024

Current clinical guidelines fall short in accurately identifying HCM patients at risk for sudden cardiac death due to VA.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Risk Factors Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Patients with adult congenital heart disease are at risk for ventricular arrhythmias (VAs) or sudden cardiac death.

Sudden Cardiac Death 40

Sudden Cardiac Death Tachycardia Congenital Heart Disease Congenital 40

HeartRhythm

JUNE 3, 2024

Most patients with VT and structural heart disease preparing for ablation either have or are about to receive an implantable cardioverter defibrillator (ICD) shortly after the procedure to prevent sudden cardiac death from recurrent ventricular arrhythmias (VA).

Sudden Cardiac Death 40

Sudden Cardiac Death Tachycardia Ablation Defibrillator 40

HeartRhythm

APRIL 30, 2024

Post-MI cardiac remodeling leads to heart failure and electrical aberrancies which result in lethal arrhythmias and sudden cardiac death. Morbidity and mortality rates after Myocardial Infarction (MI) remain high despite advancements in therapy.

Myocardial Infarction 40

Myocardial Infarction Sudden Cardiac Death Heart Failure Arrhythmia 40

HeartRhythm

APRIL 30, 2024

For the past four decades, implantable cardioverter defibrillator (ICD) therapy has become the standard of care for preventing sudden cardiac death in high-risk individuals. The rate of ICD implantation has risen due to the increasing population age and the growing prevalence of cardiac arrhythmias.

Atrial Fibrillation 40

Atrial Fibrillation Defibrillator Sudden Cardiac Death Tachycardia 40

HeartRhythm

APRIL 30, 2024

Nearly 50% of patients with AFib have comorbid obstructive sleep apnea (OSA), and 75% of OSA patients report some form of arrhythmia. Untreated OSA increases likelihood of poor outcomes for AFib patients including failed treatment, heart failure, and sudden cardiac death.

AFIB 40

AFIB Sudden Cardiac Death Outcomes Heart Failure 40

HeartRhythm

APRIL 30, 2024

Contemporary antiarrhythmic treatment of Timothy syndrome 1 (TS1) is inadequate to prevent sudden cardiac death. Using electroanatomic mapping (EAM) we discovered cardiac activation delay, which creates the milieu for functional reentrant ventricular arrhythmias.

Sudden Cardiac Death 40

Sudden Cardiac Death Pharmacology Electrophysiology Arrhythmia 40