Circulation

AUGUST 4, 2024

Despite early evidence of an antiarrhythmic role of n-3 PUFA in the prevention of sudden cardiac death and postoperative and persistent atrial fibrillation (AF), subsequent well-designed randomized trials have largely not shown an antiarrhythmic benefit.

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Sudden Cardiac Death Arrhythmia Atrial Fibrillation Circulation 81

HeartRhythm

APRIL 29, 2024

The association between alcohol consumption and risk of sudden cardiac death and/or fatal ventricular arrhythmia remains controversial.

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Sudden Cardiac Death Arrhythmia Risk Factors 40

Open Heart

NOVEMBER 21, 2024

Background Ventricular arrhythmias (VAs) frequently occur in the acute phase of myocarditis. Possible arrhythmic recurrences and the risk of sudden cardiac death (SCD) in this setting are reasons for concern, and limited data have been published to guide clinical management of these patients.

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HeartRhythm

AUGUST 7, 2024

Despite improved childhood survival in congenital heart disease (CHD) due to advances in management, late-onset sudden cardiac death (SCD) from malignant ventricular arrhythmias remains a leading cause of mortality in adults with CHD (ACHD).

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Medical Xpress - Cardiology

JANUARY 14, 2024

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study in Heart Rhythm.

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Circulation

NOVEMBER 11, 2024

Background:Limited data exist on the incidence of severe QT prolongation (SQTP) in patients using antipsychotics or antidepressants and the associated risk of ventricular arrhythmias (VA) and sudden cardiac death (SCD).Aims:This

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HeartRhythm

JANUARY 13, 2024

The increased risk of arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation has been a prominent safety pharmacology concern for the last 30 years.

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HeartRhythm

APRIL 30, 2024

The relationship between sarcopenia and ventricular arrhythmia (VA) is unknown. Sarcopenia is a geriatric syndrome featuring muscle mass, strength, and function loss. It is strongly associated with faster progression of cardiovascular diseases and an increased risk of mortality.

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The British Journal of Cardiology

OCTOBER 8, 2024

Patients with such variants can present with a wide spectrum of arrhythmias but sudden death is generally considered rare. Pathogenic genetic variants in the HCN4 (hyperpolarisation-activated and cyclic nucleotide-gated channel) gene can cause sinus node dysfunction, disrupting the function of the pacemaker region of the heart.

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Sudden Cardiac Death Pacemaker Arrhythmia Outcomes 40

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death.

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HeartRhythm

APRIL 30, 2024

Mitral annular disjunction (MAD) increases the risk of ventricular arrhythmias (VAs) and sudden cardiac death in patients with mitral valve prolapse (MVP), but its arrhythmogenic basis is unknown.

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Journal of Cardiovascular Pharmacology

MAY 7, 2024

Concerns regarding the risk of cardiac arrhythmia and death have been raised, yet the burden of HCQ and CQ-related cardiac toxicities remains unclear. Concerns regarding the risk of cardiac arrhythmia and death have been raised, yet the burden of HCQ and CQ-related cardiac toxicities remains unclear.

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Sudden Cardiac Death Arrhythmia Article Outcomes 40

HeartRhythm

OCTOBER 9, 2024

Triggers for and/or the occurrence of sudden cardiac death (SCD), and cardiac arrhythmias seem to follow such daily patterns. These clocks are found in virtually all cells in the body, including cardiomyocytes.

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HeartRhythm

NOVEMBER 13, 2023

Arrhythmogenic role of epicardial adipose tissue (EAT) in atrial arrhythmias is well established, but its effect on ventricular arrhythmias has been significantly less investigated. Since ventricular arrhythmias are thought to cause 75% to 80% of cases of sudden cardiac death, this is not a trivial issue.

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DAIC

FEBRUARY 22, 2024

The severity of the condition can vary within families, with some family members exhibiting minor symptoms while others may die of heart failure or an arrhythmia causing sudden cardiac death. DCM can be silent for months to years before symptoms begin. Eventually heart failure may develop, which is late-phase disease.

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HeartRhythm

APRIL 30, 2024

Examination of previously reported predictors of lethal ventricular arrhythmias or sudden cardiac death (VA/SCD) by ECG in Brugada syndrome (BrS) is a manual measurement and lacks objectivity.

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HeartRhythm

APRIL 30, 2024

Inherited arrhythmias (IAs) account for a significant proportion of sudden cardiac death (SCD) in young patients without overt heart disease. Recent studies have suggested that substantial proportion of IAs is much prevalent in East Asian people.

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Pediatrics Sudden Cardiac Death Arrhythmia Heart Disease 40

Ken Grauer, MD

JUNE 27, 2024

He developed cardiac arrest shortly after the ECG in Figure-1 was recorded. What is the most likely cause of this arrhythmia? Pleomorphic VT and Sudden Cardiac Death — Editorial by Liu and Josephson on potential mechanisms to explain the ECG appearance of Pleomorphic VT.

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Open Heart

MARCH 8, 2024

The wearable cardioverter defibrillator (WCD) is becoming a more and more widely used instrument for the prevention of sudden cardiac death of patients either with a secondary prevention implantable cardioverter defibrillator indication or with a transient high risk of sudden cardiac death.

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HeartRhythm

JANUARY 8, 2025

Brugada syndrome (BrS) is a genetic heart disease that predisposes individuals to ventricular arrhythmias and sudden cardiac death. Although implantable cardioverter-defibrillators (ICDs) and quinidine are primary treatments, recurrent BrS-triggered ventricular arrhythmias can persist.

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Sudden Cardiac Death Ablation Defibrillator Arrhythmia 40

Frontiers in Cardiovascular Medicine

MARCH 13, 2024

The issue is relevant since some arrhythmias are associated to sudden cardiac death occurring in young patients, and the overall risk does not cease during the early postpartum period. Arrhythmias were documented in all the patients during the first cardiological assessment.

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Cardiomyopathy Sudden Cardiac Death Outpatient Inpatient 59

Heart BMJ

FEBRUARY 12, 2024

This approach has delivered a novel perspective on arrhythmia management, with important distinctions from other policymakers’ recommendations.

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Arrhythmia Sudden Cardiac Death Atrial Fibrillation Heart Rhythm 40

HeartRhythm

AUGUST 27, 2024

Sleep-disordered breathing (SDB) increases the risk of cardiac arrhythmias and sudden cardiac death.

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Sudden Cardiac Death Arrhythmia 40

HeartRhythm

APRIL 30, 2024

Repolarization heterogeneities are known to significantly influence susceptibility to arrhythmias, a leading cause of sudden cardiac death.

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HeartRhythm

APRIL 30, 2024

Wearable cardioverter-defibrillator (WCD) is an alternative option for the prevention of sudden cardiac death in patients at high risk for malignant ventricular arrhythmias.

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HeartRhythm

JANUARY 17, 2024

Sudden cardiac death in children and young adults is a relatively rare but tragic event whose pathophysiology is unknown at the molecular level. Evidence indicates that the main cardiac sodium channel (NaV1.5) and the strong inward rectifier potassium channel (Kir2.1)

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Frontiers in Cardiovascular Medicine

DECEMBER 22, 2024

ObjectivesThe occurrence of sudden cardiac death (SCD) in competitive athletes has led to a discussion about appropriate preparticipation screening models. The role of an electrocardiogram (ECG) in routine testing remains controversial in current guidelines. A staged preparticipation screening was performed.

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Sudden Cardiac Death Electrocardiogram Congenital Arrhythmia 52

Journal of Cardiovascular Electrophysiology

FEBRUARY 8, 2024

Patients with Brugada syndrome who are asymptomatic and have no ventricular tachycardia/ventricular fibrillation inducibility by programmed electrical stimulation are at extremely low risk of experiencing late life-threatening arrhythmias. Methods Patients with BrS ( n  = 523; mean age, 51 ± 13 years; male, n  = 497) were enrolled.

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HeartRhythm

JANUARY 29, 2024

The main result of the CAST (Cardiac Arrhythmia Suppression Trial), shown in Figure 1,1 was completely unexpected: The suppression of ventricular ectopy with antiarrhythmic drugs (AADs) was associated with an increased incidence of lethal ventricular arrhythmias in patients with post–myocardial infarction (post-MI) at high risk of sudden cardiac death (..)

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Sudden Cardiac Death Myocardial Infarction Arrhythmia 40

Physiologically Speaking

FEBRUARY 28, 2024

A comprehensive list of marathon-related deaths on Wikipedia contains 47 cases of “death by marathon” in the U.S. A list of the causes of death reveals an underlying pattern. Many, but not all, are cardiac-related issues (i.e., heart attack, arrhythmia, underlying congenital heart abnormality).

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HeartRhythm

APRIL 30, 2024

Current clinical guidelines fall short in accurately identifying HCM patients at risk for sudden cardiac death due to VA.

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DAIC

JANUARY 19, 2024

Chugh’s leadership in arrhythmia research and care is extraordinary,” said Eduardo Marbán, MD, PhD , executive director of the Smidt Heart Institute. Particularly, his contributions to the sudden cardiac arrest medical knowledge base have changed the way we think about this deadly condition that we might be able to prevent on a larger scale.”

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HeartRhythm

APRIL 30, 2024

Patients with adult congenital heart disease are at risk for ventricular arrhythmias (VAs) or sudden cardiac death.

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Frontiers in Cardiovascular Medicine

JUNE 3, 2024

During the intravenous lacosamide infusion, the patient developed sudden cardiac arrest caused by ventricular arrhythmias necessitating resuscitation. Of note, the patient had a family history of sudden cardiac death.

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HeartRhythm

APRIL 30, 2024

Long QT syndrome is most commonly an inherited condition associated with a risk of sudden cardiac death. It is recognized that LQTS in the fetus may present as sinus bradycardia (SB), functional 2:1 atrioventricular block and ventricular arrhythmias (VA).

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HeartRhythm

APRIL 30, 2024

Studies of sudden cardiac death (SCD) risk intend to specify substrate for fatal arrhythmia rescuable by defibrillator but presume cardiac cause. The Postmortem Systematic Investigation of SCD (POST SCD) study showed nearly half of presumed SCDs (pSCDs) are due to non-arrhythmic causes (e.g.,

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HeartRhythm

APRIL 30, 2024

There is an unmet need for better risk stratification for sudden cardiac death in the era of primary prevention ICD therapy. Scar burden on LGE-CMR imaging may be a risk marker for ventricular arrhythmia post-myocardial infarction (MI).

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