HeartRhythm

MAY 28, 2024

We and others have investigated techniques for effective hiPSC differentiation and maturation by providing a tissue-specific microenvironment to encourage physiologically relevant model systems.

Arrhythmia 40

Arrhythmia Physiology Research 40

HeartRhythm

MARCH 31, 2025

Increased dispersion of ventricular repolarization is associated with increased risk of ventricular arrhythmias. Conventional CRT has been shown to increase dispersion, likely through reversal of the physiological transmural action potential gradient induced by LV epicardial pacing.

Physiology 40

Physiology Technology Arrhythmia 40

HeartRhythm

MARCH 31, 2025

INa,L is a small sustained inward current that flows through the action potential plateau and is linked to fatal arrhythmias. INa,L regulation is controlled by a host of proteins, in physiological and pathological states. However, little is known regarding pathways that negatively regulate INa,L.

Physiology 40

Physiology Arrhythmia 40

HeartRhythm

APRIL 2, 2025

Cardiac arrhythmias pose a major public health problem and pharmacological intervention remains key to their therapy. Our modernized antiarrhythmic drug (AAD) classification reflected and sought to facilitate such fundamental physiological and clinical development.

Public Health 40

Public Health Pharmacology Physiology Arrhythmia 40

HeartRhythm

APRIL 9, 2025

The intrinsic cardiac nervous system is a complex system that plays a critical role in the regulation of cardiac physiological parameters and has been shown to contribute to cardiac arrhythmias. To date, several types of neurons with distinct neurochemical and electrophysiological phenotypes have been identified.

Electrophysiology 40

Electrophysiology Physiology Arrhythmia 40

HeartRhythm

JANUARY 25, 2024

Early recurrence of atrial arrhythmia (ERA) is commonly seen following catheter ablation of atrial fibrillation (AF), with reported incidences of up to 61% in the first three months.1 1 ERA is often attributed to transient inflammation induced by tissue damage during ablation and short-term imbalances in autonomic innervation.

Atrial Fibrillation 45

Atrial Fibrillation Ablation Physiology Arrhythmia 45

Circulation: Arrhythmia and Electrophysiology

FEBRUARY 10, 2025

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. While any arrhythmia patient may recur after acutely successful ablation, AF is unusual in that patients may have long-term arrhythmia freedom despite a lack of acute success. The external validation cohort showed similar results (area under the curve=0.81

Atrial Fibrillation 40

Atrial Fibrillation Ablation Physiology Arrhythmia 40

DAIC

APRIL 18, 2024

This forms the physiologic rationale for the accepted convention of a three-month blanking period, during which arrhythmia recurrences are presumed to be relatively benign and not indicative of treatment failure. However, this reasoning disregards valuable data regarding early arrhythmia recurrences and their potential significance.

Atrial Fibrillation 111

Atrial Fibrillation Ablation Heart Rhythm Article 111

MIBHS

JANUARY 31, 2025

The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. Risk Reduction Data from wearables can identify potential risks, such as undiagnosed arrhythmias or hypertension, allowing healthcare teams to address these issues before surgery.

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

Journal of Cardiovascular Electrophysiology

JANUARY 4, 2024

Abstract Introduction Dual atrioventricular nodal non-reentrant tachycardia (DAVNNT) is a rare and challenging-to-diagnose arrhythmia, without previous reports associating it with a leftward inferior extension (LIE). Methods Diagnosis was made using adenosine triphosphate (ATP) injection during atrial pacing in a suspected DAVNNT patient.

Tachycardia 40

Tachycardia Physiology Arrhythmia Ablation 40

ECG Guru

JULY 31, 2023

The ECG shows a sinus rhythm with significant sinus arrhythmia. The heart rate increases with inspiration and decreases with expiration, which is called respiratory sinus arrhythmia. The QRS-axis is between 60 and 90 degrees, which is physiological at this age. Is there cause for concern?

Physiology 40

Physiology Arrhythmia 40

Frontiers in Cardiovascular Medicine

JULY 2, 2024

It is proven challenging managing chronic cardiovascular illnesses like atherosclerosis, arrhythmias, and diverse cardiomyopathies. Several approaches have been found in the current literature, aiming at improving physiological acceptance, i.e., to reduce toxicity. In certain cases, there is no approved treatment.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Physiology Biomarkers 52

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Electrocardiogram in clinic showed sinus arrhythmia with early repolarization and no ischemic changes. A 14-year-old male with no significant medical history presented with intermittent palpitations for 2–3 months that occurred at rest and were associated with light-headedness.

Chest Pain 59

Chest Pain Exercise Echocardiogram Electrocardiogram 59

Ken Grauer, MD

DECEMBER 23, 2023

KEY Point: Knowing that the most commonly overlooked arrhythmia is AFlutter — suggests that the BEST way to avoid missing the diagnosis of AFlutter is simply to THINK of AFlutter whenever you have a regular SVT at a rate close to 150/minute ( in which you do not clearly see upright sinus P waves in lead II ).

Blog 175

Blog Tachycardia Tricuspid Physiology 175

Dr. S. Venkatesan MD

JUNE 16, 2024

Any deviation or trespassing results in arrhythmia. Like hemodynamics of blood , an “electro-dynamic” flow cycle exists that is critically important both in physiology and pathology. Like coronary blood flow, intra-cardiac electricity must flow in a pre-designated path at a specific time interval with absolute discipline.

Ablation 52

Ablation Physiology Technology Bicuspid/Mitral 52

Circulation: Arrhythmia and Electrophysiology

DECEMBER 21, 2023

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:MicroRNA-1 (miR1), encoded by the genesmiR1-1andmiR1-2, is the most abundant microRNA in the heart and plays a critical role in heart development and physiology.

Electrophysiology 40

Electrophysiology Myocardial Infarction Atrial Fibrillation Arrhythmia 40

Circulation

NOVEMBER 11, 2024

Physiological class (PC) was determined by clinicians according to the 2018 AHA/ACC guidelines. Feature-tracking of SSFP cine was retrospectively utilized to quantify radial, circumferential, and longitudinal strain in both 2 and 3 dimensions. Clinical events (e.g., for each) except 3D global radial strain.

Outcomes 40

Outcomes Congenital Physiology Heart Failure 40

MIBHS

NOVEMBER 30, 2023

The exact mechanisms behind this link are complex, but it’s believed that the combination of lifestyle factors associated with depression (such as poor diet, lack of exercise, and smoking) and the physiological effects of depression on the body (including inflammation and blood clotting) can contribute to heart problems.

Blood Pressure 52

Blood Pressure Heart Disease Blood Clot Physiology 52

Dr. Smith's ECG Blog

JANUARY 5, 2024

And, the drug does provide physiologic benefits for a patient with an acute cardiac event ( ie, it helps to relieve anxiety as well as pain — which may decrease activation of autonomic nervous system activity — often resulting in reduced heart rate, blood pressure, venous return and myocardial oxygen demand — Murphy et al: StatPearls, 2023 ).

Angina 119

Angina Plaque Document Stents 119

Ken Grauer, MD

MARCH 23, 2023

A series of cardiac arrhythmias were seen during the course of her resuscitation — including the interesting arrhythmia shown in the long lead II of Figure-1. PEARL # 5: The simple act of labeling P waves can be invaluable for solving an arrhythmia. Figure-6: Laddergram illustration of the mechanism in today's arrhythmia.

Blog 78

Blog Tachycardia Arrhythmia Atrial Flutter 78

All About Cardiovascular System and Disorders

MAY 2, 2024

It is a physiological adaptation helping athletes perform physical tasks better than non-athletes. Though sinus bradycardia is usual, other abnormalities like sinus arrhythmia, sinus arrest, wandering atrial pacemaker and coronary sinus rhythm have been described. References 1.Prior Prior DL et al. The athlete’s heart. Athlete’s heart.

Exercise 40

Exercise Cardiomyopathy Blood Pressure Physiology 40

Circulation

NOVEMBER 11, 2024

6h postdose PR intervals physiologically adjusted to changing HR, and stayed within normal range. Findings also confirm previous healthy volunteer trials with IR NIC highlighting no tendency promoting arrhythmia in normal, non-ischemic myocardium.

Angina 40

Angina Electrophysiology Physiology Arrhythmia 40

Dr. Smith's ECG Blog

SEPTEMBER 9, 2020

== MY Arrhythmia Case by K EN G RAUER, MD ( 9/9/2020 ): == PREFACE: Recognition of the presence ( or absence ) of AV block is a common problem in emergency medicine. I find it helpful in sorting out complex arrhythmias to search out P waves at an early point in the process. Is There a Regular P Wave Rhythm?

Arrhythmia 52

Arrhythmia Physiology Hospital Blog 52

Dr. Sanjay Gupta

SEPTEMBER 25, 2022

An ectopic heartbeat is a type of arrhythmia, or an irregular heartbeat. This can then become a vicious cycle – if we feel anxious, frightened, or stressed in response to an ectopic beat this can lead to physiological symptoms associated with the stress response including changes to our heart rate. What are ectopic heartbeats?

Heart Attack 52

Heart Attack Heart attacks Physiology Article 52

Dr. Smith's ECG Blog

JANUARY 9, 2024

AV synchrony and physiologic ventricular depolarization the hemodynamics improved. Lowering the back up rate (LRL) of the ICD/pacer allowed for an intrinsic rhythm with physiologic AV conduction and normal AV synchrony with resultant increase in stroke volume and cardiac outpt. Why was it Wrong to Think the Rhythm was AFlutter?

Tachycardia 118

Tachycardia Electrophysiology Atrial Flutter Ischemia 118

Dr. Smith's ECG Blog

APRIL 6, 2023

Taking a Closer LOOK : There is a fairly marked sinus arrhythmia ( RED arrows in Figure-2 ). PEARL # 1: It is common with 2nd- and 3rd-degree AV block to see a "ventriculophasic" sinus arrhythmia. I've also carefully measured all P-P intervals in milliseconds — to illustrate the surprisingly marked sinus arrhythmia.

Arrhythmia 52

Arrhythmia Atrial Fibrillation AFIB Outpatient 52

All About Cardiovascular System and Disorders

APRIL 1, 2024

Another problem with atrial switch operation is that, they are likely to have atrial arrhythmias, and several other problems and the physiology is not exact as in case of arterial switch operation. Long term results are much better than atrial switch operations.

Pulmonary 52

Pulmonary Stenosis Anatomy Physiology 52

Dr. Smith's ECG Blog

JANUARY 6, 2024

The atrial rate is around 120 beats per minute, which indicates high adrenergic state and physiologic distress! Never forget that sinus tachycardia is the scariest arrhythmia. This is sinus tachycardia (rhythm) with complete heart block (AV node function) with ventricular escape rate just below 30.

Blog 110

Blog Ischemia Tachycardia STEMI 110

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

myocardial infarction), arrhythmias, valvular pathology, shunts, or outflow obstructions. Any alteration in physiology can change "compensated" AS to "decompensated" AS. Inotropes and Vasopressors: Review of Physiology and Clinical Use in Cardiovascular Medicine. Am J Cardiol 2011;107:495-500. Circulation. 2008;118:1047-1056.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Open Heart

JANUARY 19, 2025

Introduction Data on the characteristics and outcomes of pregnancy and among patients with Fontan physiology are limited. Conclusions Over one-third of women with Fontan physiology in our cohort had a documented pregnancy. We aimed to evaluate the immediate and long-term outcomes among these patients who were followed at our centre.

Congenital Heart Disease 52

Congenital Heart Disease Outcomes Physiology Arrhythmia 52

Dr. Smith's ECG Blog

OCTOBER 13, 2022

In other cases, the bypass tracts conduct intermittently, depending upon other factors such as cardioactive medication use, physiological stressors with catecholamine release, the development of coronary ischemia, and normal aging.”[3] Delta waves are seen in 11/12 leads.

Chest Pain 52

Chest Pain Myocardial Infarction Ischemia STEMI 52

Dr. Smith's ECG Blog

JULY 3, 2020

In addition to correcting hypocalcemia — IV calcium gluconate works within minutes to minimize the adverse effect of elevated extracellular K+ on myocytes, by restoring a more normal electrical gradient across cardiac cell membranes ( in so doing, reducing the risk of malignant ventricular arrhythmias ).

Hemorrhage 52

Hemorrhage Critical Care Blood Pressure Laboratory 52

Open Heart

SEPTEMBER 13, 2024

Background Pregnant patients with single ventricle (SV) physiology carry a high risk of spontaneous pregnancy loss (SPL), yet the clinical factors contributing to this risk are not well defined. Atrial arrhythmias were present in 16 (80%), Fontan-associated liver disease (FALD) in 15 (75%) and FALD stage 4 in 9 (45%).

Physiology 52

Physiology Risk Factors Arrhythmia Outcomes 52

Dr. Smith's ECG Blog

NOVEMBER 26, 2018

In some cases the ischemia can be seen "through" the flutter waves, whereas in other cases the arrhythmia must be terminated before the ischemia can be clearly distinguished. This case represents the same physiologic event as OMI in terms of the result on the myocardium, therefore with identical ECG features, however there may not be ACS!

Ischemia 52

Ischemia Atrial Flutter Arrhythmia Tachycardia 52

DAIC

APRIL 22, 2025

FAHA, dean of the graduate school and a professor of physiology at the Medical College of Georgia at Augusta University in Augusta, Georgia, and will include a collaboration with a team from Augusta University College of Science and Mathematics.

Research 52

Research Blood Pressure Risk Factors Obesity 52

Heart BMJ

FEBRUARY 26, 2025

p=0.023) and fewer ventricular arrhythmias during exercise testing. High-intensity activity-related events were associated with higher European Society of Cardiology sudden cardiac death risk scores (median 4.9

Sudden Cardiac Death 59

Sudden Cardiac Death Cardiomyopathy Exercise Risk Factors 59

Dr. Smith's ECG Blog

JANUARY 23, 2024

VT is the second most common presenting arrhythmia. Vaso or inotropic medications are not harmless, and can precipitate life threatening arrhythmias. The physiologic reason for this — is thought to be the result of momentarily increased circulation from mechanical contraction arising from the "sandwiched in" QRS complex.

Tachycardia 106

Tachycardia Arrhythmia Heart Disease Sudden Cardiac Death 106