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Background Atrial arrhythmias (AA) and heartfailure (HF) are major causes of hospitalisation in adult congenital heart disease (ACHD). Dates of first AA and HF presentations were documented, and outcomes of RFA, including acute and long-term success, were assessed.
Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heartfailure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.
Acute decompensated heartfailure (ADHF) is common in hospitalized patients, with cardiac amyloidosis being a challenging subset due to protein deposition creating a unique substrate for arrhythmias. Data on the prevalence and outcomes of arrhythmias in ADHF with cardiac amyloidosis is limited.
Journal of the American Heart Association, Ahead of Print. BackgroundPDE2 (phosphodiesterase 2) is upregulated in human heartfailure. Cardiac PDE2transgenic mice are protected against contractile dysfunction and arrhythmias in heartfailure but whether an acute elevation of PDE2 could be of therapeutic value remains elusive.
IV lidocaine is used to treat refractory ventricular arrhythmia (VA). Rapid lidocaine administration can cause dose-dependent reductions in ventricular contractility, arterial pressure, and heart rate (HR). There is little data describing clinical outcomes of patients with HF, AF, and VA receiving lidocaine.
Methods and results TRED-HF was a randomized trial investigating heartfailure therapy withdrawal in patients with recovered DCM over 6months. Clinical outcomes are reported in a non-randomized fashion from enrolment and from the end of the trial.
Abstract Left ventricular assist device (LVAD) implantation is an established treatment for patients with advanced heartfailure refractory to medical therapy. However, the incidence of ventricular arrhythmias (VAs) is high in this population, both in the acute and delayed phases after implantation.
Publication date: Available online 11 June 2024 Source: The American Journal of Cardiology Author(s): Steven Brady, Eldon Matthia, Steve Antoine, Juan Aranda, William Miles, Juan Vilaro, Mohammad Al-Ani, Olusola Oduntan, Yi Guo, Yujia Li, Mustafa Ahmed, Alex Parker
Background Echocardiography-guided percutaneous intramyocardial alginate-hydrogel implantation (PIMAHI) is a novel treatment approach for heartfailure (HF). During PIMAHI treatment, no sustained arrhythmia, pericardial, or pleural effusion occurred. We validated PIMAHI safety and efficacy in canine HF models. vs. 6.8 ± 0.2 mm,
tim.hodson Thu, 04/24/2025 - 10:37 April 23, 2025 The Heart Rhythm Society (HRS) has released a framework outlining criteria for establishing an Atrial Fibrillation (AF) Center of Excellence (CoE) and key operational standards to provide multidisciplinary care for AF patients. million adults. million adults.
Atrial fibrillation (AF) is a common arrhythmia in patients with heartfailure (HF). The coexistence of these conditions can further induce structural changes and result in worsened outcomes such as stroke, HF decompensation, poorly controlled AF, and mortality [1].
Cardiac resynchronization (CRT) with biventricular pacing (BVP) is recognized as an option to reduce mortality in patients with heartfailure with reduced ejection fraction (HFrEF). Left bundle branch area pacing (LBBAP) is an emerging role in achieving resynchronization in HFrEF and is thought to be a safe alternative to BVP.
Genetic predisposition to ventricular scarring is associated with heartfailure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.
Arrhythmias can lead to cardiac arrest (CA) and heartfailure. When intractable, heart transplant (HTX) can become the only viable treatment. This rare, high-risk cohort has not been reported as a distinct group.
Abstract Aims The CASTLE-HTx trial showed the benefit of atrial fibrillation (AF) ablation compared to medical therapy in decreasing mortality, need for left ventricular assist device implantation or heart transplantation (HTx) in patients with end-stage heartfailure (HF).
Arrhythmias, and in particular atrial fibrillation (AF), are one of the greatest healthcare challenges of our time. Hospitalisation due to this condition is exponentially growing, and now outnumbers those for both heartfailure and myocardial infarction.
Ventricular arrhythmias and heartfailure are common presentations of cardiac sarcoidosis (CS). Guidelines support implantable cardioverter-defibrillator (ICD) for many CS patients with reduced ejection fraction, but arrhythmic outcomes are poorly understood.
Its effects on the heart are particularly alarming, as smoking significantly increases the risk of cardiovascular diseases (CVDs) and complicates medical procedures such as minimally invasive or bloodless heart surgeries. Smokings Impact on Surgery When heart surgery is necessary, smoking complicates both the procedure and recovery.
European Heart Rhythm Association (EHRA) Congress Date: April 7-9, 2024 Location: Berlin, Germany and online Overview: The yearly gathering of the European Heart Rhythm Association (EHRA) unites scientists, healthcare professionals, and other stakeholders engaged in the global management of arrhythmias. Hashtag: #ESCPrev2024 5.
Outcomes of ablation with the FARAPULSE PFA System – a nonthermal treatment in which electric fields selectively ablate heart tissue – will be compared to outcomes following use of anti-arrhythmic drug (AAD) therapy, which is commonly prescribed for patients living with persistent AF.
Nevertheless, studies on the long-term outcomes of catheter ablation in patients with dilated cardiomyopathy are limited. The clinical outcomes of catheter ablation and medical therapy were compared using the propensity score matched method. years following catheter ablation.
Tricuspid and mitral valves are debilitating conditions that can lead to arrhythmias, hypertension, and heartfailure. Leon added, “This new mitral-tricuspid valve center will mobilize a decade of specialized experiences among our contributing physicians to provide optimal clinical outcomes for our sickest patients.”
At this point, there was no improvement in LV function and he was out of the convalescent phase of his MI, so the decision was made to install an ICD for arrhythmia prophylaxis. He now has regular appointments with the heartfailure team. The R waves have not recovered, however.
AF, the most common arrhythmia in adults, contributes to outcomes such as heartfailure and stroke. Despite this, many underlying molecular mechanisms remain to be elucidated.
Ventricular arrhythmias are common in adult and pediatric patients (pts) with end-stage heartfailure requiring ventricular assist devices (VADs). Studies assessing the utility of implantable cardiac defibrillator (ICD) placement in adult patients with VADs show conflicting data regarding its mortality benefit.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults, leading to significant cardiovascular complications such as ischemic stroke, heartfailure, and myocardial infarction. Pulmonary vein isolation (PVI) is a well-established treatment for rhythm control in patients with AF.
Cardiovascular composite end points included major adverse cardiovascular events plus (a composite end point of allcause mortality, myocardial infarction, stroke, or heartfailure) and cardiac arrhythmias (a composite end point of new onset atrial fibrillation and other atrial and ventricular arrythmias), all in the hospital setting.
Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is often accompanied by atrial fibrillation (AF), atrial flutter (AFL), and atrial tachycardia (AT), which are difficult to control because beta-blockers and antiarrhythmic drugs can worsen heartfailure (HF).
change in PC, initiation or escalation of diuretics, mortality, arrhythmias, heartfailure hospitalization) over a 5-year period were obtained through chart review.Results:Deterioration of PC was significantly associated with worsening of all strain measures (p ≤0.05 Clinical events (e.g.,
That could have a major impact on cardiogenic shock outcomes, which rely heavily on blood pressure, and are associated with long/costly hospital stays and high mortality risks. That could be a big deal in the cardiogenic shock space, which many believe is still in need of more effective treatments.
Furthermore, coexistence of hypertension and AF mutually amplifies the risk of complications, such as heartfailure and stroke. Once AF is initiated, the arrhythmia itself can further stimulate above pathways, creating a vicious cycle that allows arrhythmia perpetuation and progression from paroxysmal to non-paroxysmal types.
Health systems leveraging Guidehealth can seamlessly integrate Story Health’s program to support at-risk patients with heart conditions like heartfailure, hypertension, and arrhythmia, providing better care while also reducing the total cost of care, according to a written statement detailing the deal.
ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia. AF increases the risk of stroke, heartfailure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heartfailure.
BackgroundIschemic cardiomyopathy (ICM) is the end stage of ischemic heart disease, in which ventricular remodeling contributes to a fatal ventricular arrhythmia, worsens heart function and unfavorable outcomes, and is related to persistent chronic inflammation.
The risks of all-cause mortality and major adverse cardiac and cerebrovascular events (CVA, cardiac arrest, acute heartfailure (AHF), Ventricular arrhythmia, complete AV block, AMI, and PCI), and use of mechanical circulatory support (MCS) were assessed in adult AMC admissions with and without SID.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:A growing number of patients with tetralogy of Fallot develop left ventricular systolic dysfunction and heartfailure, in addition to right ventricular dysfunction. years) with tetralogy of Fallot and CRT were enrolled.
The Heart Rhythm Society is the international leader in science, education, and advocacy for cardiac arrhythmia professionals and patients and the primary information resource on heart rhythm disorders. Avari Silva On Saturday, Sept. Lakkireddy | Edmondo Robinson | Jose Osorio | Rod Passman | David N.
Indeed, chronic inflammation and immune dysregulation play pivotal roles in most cardiovascular conditions, including arrhythmias, atherothrombosis, ischemic heart disease, heartfailure, and valve disease. Copyright 2025 Wolters Kluwer Health, Inc. All rights reserved.
OSA disproportionately affects the 92 million Americans living with cardiovascular disease (CVD), often goes undiagnosed (1) , and doubles the risk for heartfailure and other serious cardiovascular conditions. FACC, FHRS, FHSC , Executive Medical Director, Texas Cardiac Arrhythmia Institute at St. billion (2).
We collected demographic, pre-procedural, procedural, and outcome-related variables. The most common MAE was arrhythmia, representing 46% of MAE, followed by cardiac arrest and bleeding each 20%. The leading cause of mortality was heartfailure in 51% of deceased patients. were females. MAE was present in 1.6%.
Smith Center for Outcomes Research in Cardiology and director of the cardiac critical care unit at Beth Israel Deaconess Medical Center in Boston, Mass. Kazi , vice chair of the advisory writing group, said in an AHA news release. Kazi is head of health economics and associate director of the Richard A. and Susan F.
This discussion explores the principles and practices of evidence-based cardiometabolic medicine, emphasizing the importance of integrating the latest research findings into clinical decision-making to improve patient outcomes. HeartFailure : Home-based cardiac rehabilitation is as effective as center-based programs.
In adults, arrhythmias such as atrial fibrillation and flutter are the most frequent acute cardiovascular complication. Acute heartfailure has an incidence ranging from 0.4% In pediatric patients, left ventricular systolic dysfunction and pericardial effusion are the most common cardiovascular complications.
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