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In adults with congenital heart disease (ACHD patients), atrial arrhythmias (AA) and heartfailure (HF) are common. 1 Factors related to congenital heart disease, such as underlying anatomy, surgical repair technique and scars, can all be considered as AA substrates.
Background Atrial arrhythmias (AA) and heartfailure (HF) are major causes of hospitalisation in adult congenital heart disease (ACHD). Methods In this single-centre retrospective cohort study, data from 3995 patients with ACHD were analysed.
Researchers identified a lipid that is involved in regulating cardiac ion channels, providing insights into possible mechanisms of cardiac arrhythmias in heartfailure and a potential pathway for future therapeutic development.
Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heartfailure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.
Journal of the American Heart Association, Ahead of Print. BackgroundPDE2 (phosphodiesterase 2) is upregulated in human heartfailure. Cardiac PDE2transgenic mice are protected against contractile dysfunction and arrhythmias in heartfailure but whether an acute elevation of PDE2 could be of therapeutic value remains elusive.
ABYSS suggests that long-term beta-blocker therapy is recommended after an MI, even in the absence of heartfailure, arrhythmia or uncontrolled hypertension.
Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%. It can be associated with reduced quality of life and complications such as heartfailure and stroke. Pulmonary vein isolation (PVI) is the most effective treatment for rhythm control.
Abstract Patients presenting with or alerting emergency networks due to acute heartfailure (AHF) form a diverse group with a plethora of symptoms, risks, comorbidities, and aetiologies. Scientific guidelines provide clear recommendations for the management of arrhythmias in chronic heartfailure patients.
Heartfailure (HF) is recognized as an epidemic in the contemporary world, impacting around 1%–2% of the adult population and affecting around 6 million Americans. Among the most serious manifestations associated with HF is arrhythmia due to the electrophysiological changes within the cardiomyocyte.
For full discussion of the case — CLICK HERE — ECG Rhythm Overview: A 12-year-old boy was admitted to our hospital with severe myocardial dysfunction and chaotic rhythm with tachy- and bradycardic arrhythmias. Hope this helps — :) ECG-3 — I see sinus bradycardia and arrhythmia.
Methods and results TRED-HF was a randomized trial investigating heartfailure therapy withdrawal in patients with recovered DCM over 6months. The primary outcome was relapse defined as 10% reduction in left ventricular ejection fraction to 400ng/L, or clinical features of heartfailure.
Abstract Left ventricular assist device (LVAD) implantation is an established treatment for patients with advanced heartfailure refractory to medical therapy. However, the incidence of ventricular arrhythmias (VAs) is high in this population, both in the acute and delayed phases after implantation.
Impact of guideline-directed medical therapy for heartfailure after left ventricular ejection fraction (LVEF) improvement in arrhythmia-induced cardiomyopathy. ( A ) Study flow chart. ( B ) Changes in renin-angiotensin-system (RAS) inhibitors and beta-blockers (BB) prescriptions after LVEF improvement. (
An abnormal myocardial Ca2+ transient is linked to heartfailure and ventricular arrhythmias. This narrative review evaluates the role of aberrant Ca2+ release synchrony in the pathophysiology of cardiomyopathies and ventricular arrhythmias.
Introduction Heart transplantation (HT) is the only treatment option in children with heartfailure secondary to cardiomyopathies and non-reparable congenital heart diseases. 111.87), arrhythmias were detected in 9 (33%) patients. We did not identify significant risk factors for arrhythmias post-HT.
The global health challenge posed by cardiac arrhythmias, particularly atrial fibrillation (AF), is significant, with heightened risks of stroke, heartfailure, and systemic embolism1.
Robotic Magnetic Navigation introduces the benefits of robotic precision and safety to cardiac ablation, a common minimally invasive procedure to treat arrhythmias. Tens of millions of individuals worldwide suffer from arrhythmias – abnormal heart rhythms that result when the heart beats too quickly, too slowly, or with an irregular pattern.
The progression of heartfailure (HF) is associated with detrimental myocardial structural changes, predisposing HF patients to an increased risk of ventricular arrhythmia (VA).
Genetic predisposition to ventricular scarring is associated with heartfailure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.
Publication date: Available online 11 June 2024 Source: The American Journal of Cardiology Author(s): Steven Brady, Eldon Matthia, Steve Antoine, Juan Aranda, William Miles, Juan Vilaro, Mohammad Al-Ani, Olusola Oduntan, Yi Guo, Yujia Li, Mustafa Ahmed, Alex Parker
Hashtag: #ACC25 European Heart Rhythm Association (EHRA) Congress 2025 Date: 30 March to 1 April 2025 Location: Vienna and online Overview: The yearly gathering of the European Heart Rhythm Association (EHRA) unites scientists, healthcare professionals, and other stakeholders engaged in the global management of arrhythmias.
Background Echocardiography-guided percutaneous intramyocardial alginate-hydrogel implantation (PIMAHI) is a novel treatment approach for heartfailure (HF). During PIMAHI treatment, no sustained arrhythmia, pericardial, or pleural effusion occurred. We validated PIMAHI safety and efficacy in canine HF models. vs. 6.8 ± 0.2 mm,
Abstract Aims The CASTLE-HTx trial showed the benefit of atrial fibrillation (AF) ablation compared to medical therapy in decreasing mortality, need for left ventricular assist device implantation or heart transplantation (HTx) in patients with end-stage heartfailure (HF).
Clinicians should have a high degree of suspicion for cardiac sarcoidosis in patients with new heartfailure, high-grade conduction disease, ventricular arrhythmias, and known extracardiac disease.
Atrial fibrillation, or AFib, is a fast and irregular heart rhythm that, left untreated, can lead to blood clots, stroke and heartfailure. It's the most common type of arrhythmia, a potentially serious condition in which the heart beats too quickly, too slowly or in an irregular pattern.
Arrhythmias, and in particular atrial fibrillation (AF), are one of the greatest healthcare challenges of our time. Hospitalisation due to this condition is exponentially growing, and now outnumbers those for both heartfailure and myocardial infarction.
Cardiac resynchronization (CRT) with biventricular pacing (BVP) is recognized as an option to reduce mortality in patients with heartfailure with reduced ejection fraction (HFrEF). Left bundle branch area pacing (LBBAP) is an emerging role in achieving resynchronization in HFrEF and is thought to be a safe alternative to BVP.
Arrhythmias can lead to cardiac arrest (CA) and heartfailure. When intractable, heart transplant (HTX) can become the only viable treatment. This rare, high-risk cohort has not been reported as a distinct group.
Atrial fibrillation (AF) is a common arrhythmia in patients with heartfailure (HF). Catheter ablation of AF has been proven to be an effective therapeutic option for AF management in HF, particularly in heartfailure with reduced ejection fraction (HFrEF) [2, 3].
Abstract The management of heartfailure patients with continuous-flow left ventricular assist device (LVAD) patients is challenging. While one third of these patients are recipients of cardiac implantable electronic devices (CIEDs), the risk for atrial and ventricular arrhythmias may coexist.
European Heart Rhythm Association (EHRA) Congress Date: April 7-9, 2024 Location: Berlin, Germany and online Overview: The yearly gathering of the European Heart Rhythm Association (EHRA) unites scientists, healthcare professionals, and other stakeholders engaged in the global management of arrhythmias. Hashtag: #ESCPrev2024 5.
Ventricular arrhythmias and heartfailure are common presentations of cardiac sarcoidosis (CS). Guidelines support implantable cardioverter-defibrillator (ICD) for many CS patients with reduced ejection fraction, but arrhythmic outcomes are poorly understood.
Cardiac resynchronization therapy (CRT) is cornerstone of device therapy in heartfailure (HF). Arrhythmia is associated with significant morbidity and mortality in patients with HF. However, risk of arrhythmia in patients with LBBAP in comparison to biventricular pacing (BiVP) CRT is unclear.
With the unveiling of the Genesis System, Baptist Health Lexington has become the first in Kentucky, and one of the first in the world, to provide the latest advancement in robotic technology to treat cardiac arrhythmias. “We For more information: www.stereotaxis.com If you enjoy this content, please share it with a colleague
“With the Genesis RMN system, we now have an unprecedented level of precision and control during cardiac ablation procedures, allowing us to target arrhythmias with unmatched accuracy while minimizing risk to our patients.” added Giuseppe Russo, General Manager of the Hospital Santa Maria della Pietà.
Journal of the American Heart Association, Ahead of Print. BackgroundCarotid intimamedia thickness (CIMT) and carotid distensibility are markers of arterial change; however, little is known of the association with incident heartfailure (HF).
Digoxin has been used in the management of chronic heartfailure (HF) and atrial fibrillation (AF) for over 250 years. However, due to concerns about arrhythmia and toxicity, its use has declined dramatically over recent decades. It is the only drug that combines an inotropic effect with a reduction in ventricular rate in AF.
Permanent pacer placement Later, a biventricular pacer was placed for " Cardiac Resynchronization Therapy (CRT) " (This is indicated for patients with LBBB and QRS duration > 130 ms and heartfailure and vastly improves heartfailure). See Dr. Karim's further thoughts on this below.
Tricuspid and mitral valves are debilitating conditions that can lead to arrhythmias, hypertension, and heartfailure. Until recently, therapeutic options for people with tricuspid and mitral valve disorders have been limited to symptom relief or high-risk surgery.
Although several studies have reported on estimating the risk of developing fatal arrhythmias from ECG findings, the use of ECG to identify the severity of heartfailure (HF) by applying deep learning (DL) methods has not been established. Objectives In hypertrophic cardiomyopathy (HCM), specific ECG abnormalities are observed.
Type 2 diabetes mellitus (T2DM) is a major risk factor for heartfailure with preserved ejection fraction and cardiac arrhythmias. Precursors of these complications, such as diabetic cardiomyopathy, remain inc.
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