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PO-03-084 GENETIC PREDISPOSITION TO ATRIAL FIBRILLATION INCREASES ISCHEMIC STROKE RISK AMONG INDIVIDUALS WITH ATRIAL FIBRILLATION

HeartRhythm

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

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Sweetened Beverages, Genetic Susceptibility, and Incident Atrial Fibrillation: A Prospective Cohort Study

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. The highest HRs (95% CIs) of AF were observed for participants at high genetic risk who consumed >2 L/wk of ASB (HR, 3.51 [95% CI, 2.94–4.19]), PJ consumption ≤1 L/wk was associated with a modestly lower risk for AF.

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The Role of Genetics in Heart Disease Risk

AMS Cardiology

It encompasses a range of conditions, including coronary artery disease, heart failure and arrhythmias. While lifestyle factors such as diet, exercise and smoking play a significant role in the development of heart disease, genetics also contribute substantially.