Remove Arrhythmia Remove Genetic predisposition Remove Outcomes
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PO-06-052 THE OCCURRENCE OF VENTRICULAR SEPTAL SCARRING, HEART FAILURE, AND GENETIC VARIANTS IN PATIENTS WITH NON-ISCHEMIC CARDIOMYOPATHY AND ARRHYTHMIA: RESULTS FROM THE PHOENIX CARDIAC GENETIC REGISTRY (PCGR).

HeartRhythm

Genetic predisposition to ventricular scarring is associated with heart failure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.

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PO-06-050 THE ASSOCIATION BETWEEN VENTRICULAR ABLATION, SEPTAL SCARRING, AND GENETIC VARIANTS: RESULTS FROM THE PHOENIX CARDIAC GENETIC REGISTRY (PCGR).

HeartRhythm

Genetic predisposition to septal scarring can result in ventricular arrhythmia and poorer ablation outcomes. There is a need to better define these genetic variants to understand clinical implications. Many commonly occurring variants continue to be described as variants of uncertain significance (VUS).

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Atrial Fibrillation in Black American Patients: A Review of Genetics, Risk Factors, and Outcomes

HeartRhythm

Atrial fibrillation (AF) is the most common arrhythmia in the U.S., Data pertaining to the American Heart Association Life’s Simple 7 (LS7) health metrics show that Black Americans have suboptimal LS7 scores compared to White Americans on average despite lower genetic predisposition to AF.

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Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy

Circulation

The aim is to assess the prevalence, clinical consequences, and genetic predisposition of reduced EF in athletes.METHODS:Young endurance athletes were recruited from elite training programs and underwent cardiac phenotyping, genetic analyses and clinical events were recorded over a mean of 4.4