HeartRhythm

APRIL 30, 2024

Genetic predisposition to ventricular scarring is associated with heart failure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.

Genetic predisposition 40

Genetic predisposition Heart Failure Arrhythmia Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Stroke Strokes 40

HeartRhythm

APRIL 30, 2024

Genetic predisposition to septal scarring can result in ventricular arrhythmia and poorer ablation outcomes. There is a need to better define these genetic variants to understand clinical implications. Many commonly occurring variants continue to be described as variants of uncertain significance (VUS).

Genetic predisposition 40

Genetic predisposition Ablation Arrhythmia Outcomes 40

HeartRhythm

NOVEMBER 5, 2024

Atrial fibrillation (AF) is the most common arrhythmia in the U.S., Data pertaining to the American Heart Association Life’s Simple 7 (LS7) health metrics show that Black Americans have suboptimal LS7 scores compared to White Americans on average despite lower genetic predisposition to AF.

Atrial Fibrillation 40

Atrial Fibrillation Risk Factors Genetic predisposition Cardiovascular Disease 40

AMS Cardiology

OCTOBER 11, 2023

It encompasses a range of conditions, including coronary artery disease, heart failure and arrhythmias. While lifestyle factors such as diet, exercise and smoking play a significant role in the development of heart disease, genetics also contribute substantially.

Heart Disease 52

Heart Disease Genetic predisposition Diet Genetic Markers 52

Circulation: Arrhythmia and Electrophysiology

MARCH 5, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. The highest HRs (95% CIs) of AF were observed for participants at high genetic risk who consumed >2 L/wk of ASB (HR, 3.51 [95% CI, 2.94–4.19]), 4.19]), and the lowest HR were observed for those at low genetic risk who consumed ≤1 L/wk of PJ (HR, 0.77 [95% CI, 0.65–0.92]).

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Electrophysiology Diet 40

Circulation

DECEMBER 17, 2023

The aim is to assess the prevalence, clinical consequences, and genetic predisposition of reduced EF in athletes.METHODS:Young endurance athletes were recruited from elite training programs and underwent cardiac phenotyping, genetic analyses and clinical events were recorded over a mean of 4.4

Genetic predisposition 77

Genetic predisposition Cardiomyopathy Sudden Cardiac Death Heart Failure 77