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The Role of Genetics in Heart Disease Risk

AMS Cardiology

It encompasses a range of conditions, including coronary artery disease, heart failure and arrhythmias. While lifestyle factors such as diet, exercise and smoking play a significant role in the development of heart disease, genetics also contribute substantially. Cardiovascular disease is a leading cause of death worldwide.

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Hypertrophic Cardiomyopathy

All About Cardiovascular System and Disorders

Genetic markers for several of these disorders are also available commercially. Palpitations can be felt if there are arrhythmias. Mid cavity obstruction in HCM is associated with apical aneurysm, systemic embolism, and arrhythmias. Sigmoidal HCM which is about 40-50% has about 10% positivity for myofilament gene.