Remove Arrhythmia Remove Electrophysiology Remove Physiology
article thumbnail

A fascinating electrophysiology case. What is this wide complex tachycardia, and how best to manage it?

Dr. Smith's ECG Blog

AV synchrony and physiologic ventricular depolarization the hemodynamics improved. Lowering the back up rate (LRL) of the ICD/pacer allowed for an intrinsic rhythm with physiologic AV conduction and normal AV synchrony with resultant increase in stroke volume and cardiac outpt. Why was it Wrong to Think the Rhythm was AFlutter?

article thumbnail

Shorten the Blanking Period After Atrial Fibrillation Ablation, Experts Say

DAIC

Two articles and an accompanying editorial in Heart Rhythm , the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society , and the Pediatric & Congenital Electrophysiology Society , published by Elsevier , address the controversy and recommend shortening the blanking period.

article thumbnail

Excitability Properties of Cardiac Calbindin Neurons: Identifying a Unique Neuronal Population

HeartRhythm

The intrinsic cardiac nervous system is a complex system that plays a critical role in the regulation of cardiac physiological parameters and has been shown to contribute to cardiac arrhythmias. To date, several types of neurons with distinct neurochemical and electrophysiological phenotypes have been identified.

article thumbnail

MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:MicroRNA-1 (miR1), encoded by the genesmiR1-1andmiR1-2, is the most abundant microRNA in the heart and plays a critical role in heart development and physiology.

article thumbnail

Comparing Phenotypes for Acute and Long-Term Response to Atrial Fibrillation Ablation Using Machine Learning

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. While any arrhythmia patient may recur after acutely successful ablation, AF is unusual in that patients may have long-term arrhythmia freedom despite a lack of acute success. The external validation cohort showed similar results (area under the curve=0.81

article thumbnail

Abstract 4140212: Cardiac Electrophysiologic Response to Single-dose AUX-001, a Once-Daily Extended-Release Nicorandil in Development for Chronic-stable Angina in Adult Healthy Volunteers under Fasting and Fed Conditions

Circulation

6h postdose PR intervals physiologically adjusted to changing HR, and stayed within normal range. Findings highlight no relevant AUX-001 effect on electrophysiological safety providing additional safety information supporting development of ER NIC.

Angina 40
article thumbnail

“Diastolic blind spots” in VT

Dr. S. Venkatesan MD

Any deviation or trespassing results in arrhythmia. The term, VT mapping has been in vogue in clinical electrophysiology for more than half a century, right from Dr.Josephson and Wellens’ days. But, just wanted to share a simple thought with the general cardiologists after going through the above article.