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Circulating microRNAs as biomarkers of Chagas cardiomyopathy

Frontiers in Cardiovascular Medicine

Methods We carried out a case-control study to identify circulating miRNAs associated with CHCM. We performed a clinical, echocardiographic, and laboratory evaluation and profiled circulating miRNA in the serum samples. Results Differences between groups were observed in clinical variables and in the analysis of miRNAs.

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Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The coronary care unit gradually evolved from a focus on rapid resuscitation from ventricular arrhythmias in acute myocardial infarction into a comprehensive cardiac intensive care unit designed to care for the sickest patients with cardiovascular disease.

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Patent Foramen Ovale Closure in Patients With and Without Nickel Hypersensitivity: A Randomized Trial

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. No significant differences were observed in documented arrhythmias, bleeding, or stroke. Background:Nickel-containing devices, such as the Amplatzer PFO Occluder and Gore Cardioform Septal Occluder (GSO), are used for transcatheter patent foramen ovale (PFO) closure.

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Pharmacological Management of Cardiac Arrhythmias in the Fetal and Neonatal Periods: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. In addition, exposure of the fetus or neonate to either persistent arrhythmias or antiarrhythmic medications may have yet-to-be-determined long-term developmental consequences. Disorders of the cardiac rhythm may occur in both the fetus and neonate.

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Gene therapy shows promise in treating heart arrhythmia: Study

Becker's Hospital Review - Cardiology

A pharmaceutical gene therapy has shown promise in treating calmodulinopathy, a rare and hard-to-treat heart arrhythmia, according to a study published Aug. 19 in Circulation.

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AHA's statement on COVID-19-associated arrhythmias: 8 takeaways

Becker's Hospital Review - Cardiology

The American Heart Association has released a scientific statement providing guidance on the management of patients with COVID-19-related cardiac arrhythmias and autonomic dysfunction. 14 in Circulation. The statement was published Oct.

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Computational Modeling of Effects of PKP2 Gene Therapy on Ventricular Conduction Properties in Arrhythmogenic Cardiomyopathy

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Evidence from experimental systems and patients indicates that ventricular myocytes inPKP2arrhythmogenic cardiomyopathy have greatly reduced electrical coupling at gap junctions and reduced Na+current density.