Remove Arrhythmia Remove Cardiomyopathy Remove Sudden Cardiac Death
article thumbnail

The role of the molecular autopsy in sudden cardiac death in young individuals

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 January 2024; doi:10.1038/s41569-024-00989-0 A molecular autopsy is undertaken in cases of sudden cardiac death with no definitive cause found after conventional autopsy, with the aim of identifying a pathological genetic variant that could account for the death.

article thumbnail

Imagenetics for Precision Medicine in Dilated Cardiomyopathy

Circulation: Genomic and Precision Medicine

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. Circulation: Genomic and Precision Medicine, Ahead of Print.

article thumbnail

The “arrhythmic” presentation of peripartum cardiomyopathy: case series and critical review of the literature

Frontiers in Cardiovascular Medicine

Peripartum Cardiomyopathy (PPCM) is a polymorphic myocardial disease occurring late during pregnancy or early after delivery. The issue is relevant since some arrhythmias are associated to sudden cardiac death occurring in young patients, and the overall risk does not cease during the early postpartum period.

article thumbnail

ATRIAL TACHYARRHYTHMIAS IN ARRHYTHMOGENIC CARDIOMYOPATHY

HeartRhythm

Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by replacement of ventricular myocardial by fibrofatty scar tissue which underlies morpho-functional ventricular abnormalities and life-threatening ventricular arrhythmias potentially responsible of sudden cardiac death (SCD), mostly in young people and athletes 1,2.

article thumbnail

Pitfalls in the diagnosis of arrhythmogenic right ventricular cardiomyopathy

HeartRhythm

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic cardiomyopathy resulting from disordered function of the intercalated discs with mainly arrhythmic manifestation, which can be difficult to diagnose because of its variable presentation. The incidence of ARVC is reported to be 1:2000 to 1:5000.

article thumbnail

Role of arrhythmic phenotype in prognostic stratification and management of dilated cardiomyopathy

European Journal of Heart Failure

Dilated cardiomyopathy with arrhythmic phenotype. Abstract Aims Dilated cardiomyopathy (DCM) with arrhythmic phenotype combines phenotypical aspects of DCM and predisposition to ventricular arrhythmias, typical of arrhythmogenic cardiomyopathy. During a median follow-up of 6 years (interquartile range 1.6–12.1),

article thumbnail

A Pilot Study of “Burst” Exercise Testing in Hypertrophic Cardiomyopathy

HeartRhythm

Hypertrophic cardiomyopathy (HCM)-related sudden cardiac death (SCD) rates with contemporary management are low; however, high-intensity exercise can induce fatal arrhythmias in HCM patients. Thus, current guidelines recommend avoiding high-intensity exercise in HCM patients at high risk for SCD1,2.