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Heart transplantation for pediatric patients with malignant arrhythmias: Indications and Outcomes

HeartRhythm

Arrhythmias can lead to cardiac arrest (CA) and heart failure. When intractable, heart transplant (HTX) can become the only viable treatment. This rare, high-risk cohort has not been reported as a distinct group.

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Abstract 4134590: Procedural Related Major Adverse Events of Cardiac Catheterization in Pediatric Patients with Cardiomyopathy: Insights from IMPACT Registry

Circulation

The most common MAE was arrhythmia, representing 46% of MAE, followed by cardiac arrest and bleeding each 20%. Conclusion:Cardiac catheterization is a safe procedure in pediatric patients with cardiomyopathy, with an overall MAE rate of 1.6%. MAE was present in 1.6%.

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Young Man with a Heart Rate of 257. What is it and how to manage?

Dr. Smith's ECG Blog

In this pediatric study, it was 71% successful and better than amiodarone. NOTE #3: In the context of a long QTc or ischemia — the finding of ST segment and/or T wave alternans may predict the occurrence of malignant ventricular arrhythmias. Procainamide is another reasonable solution to the problem.

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A man in his 70s with weakness and syncope

Dr. Smith's ECG Blog

Prior to Mizusawa's study, it was thought that the incidence of syncope, arrhythmia, or SCD in this cohort was low [7]. In light of the risk of arrhythmia events observed in the Mizusawa trial, a formal EP study might be reasonable to obtain in those with fever induced asymptomatic Brugada ECG changes to help risk stratify these patients.

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Brugada Syndrome: Diagnosis and Risk Stratification

All About Cardiovascular System and Disorders

This is the proposed mechanism of precipitation of arrhythmias in Brugada syndrome during febrile episodes. There is a potential risk for drug challenge in that life threatening ventricular arrhythmias could be precipitated. It is seldom done in pediatric age group. This leads to shortening of action potential duration.

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Hyperthermia and ST Elevation

Dr. Smith's ECG Blog

Prior to Mizusawa's study, it was thought that the incidence of syncope, arrhythmia, or SCD in this cohort was low [7]. In light of the risk of arrhythmia events observed in the Mizusawa trial, a formal EP study might be reasonable to obtain in those with fever induced asymptomatic Brugada ECG changes to help risk stratify these patients.

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Independent External Evaluation of Pediatric Hypertrophic Cardiomyopathy Risk Scores in Predicting Severe Ventricular Arrhythmias

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Sudden cardiac death is the most common cause of death in childhood hypertrophic cardiomyopathy (HCM). Recently, 2 risk scores have been developed to estimate the 5-year risk of sudden cardiac death. males), with a mean follow-up of 8.65.5