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Emergency interventions for cardiogenic shock due to decompensated aortic stenosis: a systematic review and meta-analysis

Open Heart

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain. Methods A systematic literature review and meta-analysis was performed.

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TAVR System Shows Durable Clinical Outcomes, Strong Valve Performance in Low-Risk Aortic Stenosis Patients

DAIC

Data shows, versus surgery, the Evolut transcatheter aortic valve replacement (TAVR) system delivers a numerically lower rate of all-cause mortality or disabling stroke at five years, strong valve performance and durable clinical outcomes. Reardon, M.D., Evolut TAVR vs. 9.3%

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Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis

The New England Journal of Medicine

Among patients with asymptomatic severe aortic stenosis, early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes.

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Systematic review and meta-analysis of early aortic valve replacement versus conservative therapy in patients with asymptomatic aortic valve stenosis with preserved left ventricle systolic function

Open Heart

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.

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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Cardiology Update

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. Severe SVD was defined by specific criteria.

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No Such Thing as Too Early For TAVI in Asymptomatic Severe Aortic Stenosis

American College of Cardiology

The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.

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AHA Raises Awareness on HVD

DAIC

each year, according to the American Heart Association 2025 Heart Disease and Stroke Statistical Update. AS occurs when the aortic valve narrows, restricting blood flow from the heart to the body. Learn more about hart valve disease, aortic stenosis and the American Heart Association's educational initatives at heart.org.