Heart BMJ

APRIL 10, 2025

Since the first implementation in 2002 by Alain Cribier, transcatheter aortic valve replacement (TAVR) has become a standard procedure for high-risk and elderly patients with severe aortic valve stenosis. Recently, the use of TAVR has expanded to relatively younger patients with low to moderate surgical risk.

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Aortic valve Aortic TAVR Stenosis 52

HCPLive

OCTOBER 11, 2024

be overtreating aortic stenosis. Linda Gillam, MD, MPH, discusses the idea that the cardiology community may.

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Stenosis Aortic 98

DAIC

MARCH 25, 2024

The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve).

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Stenosis Aortic Aortic valve Heart Valves 115

Frontiers in Cardiovascular Medicine

JANUARY 20, 2025

BackgroundPatients who underwent surgical repair of supravalvular aortic stenosis (SVAS) are at high risk for postoperative major adverse cardiovascular events (MACE).

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Stenosis Aortic Hospital Research 52

Frontiers in Cardiovascular Medicine

DECEMBER 11, 2024

Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, predisposes individuals to aortic stenosis and regurgitation due to valve degeneration.

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Stenosis 52

JAMA Cardiology

APRIL 5, 2024

This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.

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Stenosis Biomarkers Aortic 99

Frontiers in Cardiovascular Medicine

MARCH 20, 2025

ObjectivesRegistered, prospective, multicenter study of the short-term clinical outcomes of a novel transcatheter aortic valve system (Xcor system, Saint Medical Technology, Inc., Nanjing) to evaluate its safety and efficacy.Methods130 high risk patients with symptomatic severe AS from 11 institutions were treated with the novel Xcor system.

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Aortic valve Aortic Bicuspid/Mitral Stenosis 52

Frontiers in Cardiovascular Medicine

MARCH 9, 2025

Transcatheter aortic valve replacement (TAVR) has become a leading treatment for aortic stenosis, but managing thromboembolic and bleeding risks post-procedure remains challenging. This review examines current evidence on antithrombotic therapy after TAVR.

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Aortic valve Aortic TAVR Thrombosis 52

Med Page Today

OCTOBER 28, 2024

(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.

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TAVR Aortic Aortic valve Stenosis 105

JAMA Cardiology

JULY 16, 2024

This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.

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Stenosis Aortic valve Aortic 82

American College of Cardiology

MAY 24, 2024

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

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Aortic valve Aortic Stenosis Article 72

American College of Cardiology

MARCH 29, 2025

25 in Chicago and simultaneously published in the NEJM.

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Heart Failure Stenosis Aortic Article 75

Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

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Aortic valve Bicuspid/Mitral Aortic Aneurysm 52

Frontiers in Cardiovascular Medicine

JANUARY 16, 2025

Calcific aortic valve disease (CAVD) is a common cardiovascular condition in the elderly population. In recent years, long non-coding RNAs (lncRNAs) have emerged as significant regulators of gene expression, playing crucial roles in the occurrence and progression of various diseases.

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Aortic valve Aortic Stenosis Research 52

Medical Xpress - Cardiology

OCTOBER 29, 2024

Until now, patients with aortic stenosis—a narrowing of one of the heart's main valves—have had to wait until symptoms become severe before undergoing valve replacement.

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Stenosis Aortic Chest Pain 80

American College of Cardiology

SEPTEMBER 18, 2024

The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.

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Aortic valve Aortic Stenosis Article 64

American College of Cardiology

FEBRUARY 21, 2024

Echocardiography remains the principal imaging modality for detection and diagnosis of aortic stenosis (AS), as well as for grading of severity.

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Stenosis Aortic Article 75

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2025

IntroductionClinical evidence highlighting the efficacy and safety of transcatheter aortic valve replacement (TAVR) and the 2019 Food and Drug Administration (FDA) approval for TAVR in low-risk (younger) patients has created a demand for durable and long-lasting bioprosthetic heart valve (BHV) leaflet materials.

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Heart Valves Aortic TAVR Aortic valve 52

Heart BMJ

JANUARY 29, 2025

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Methods This prospective cohort study consecutively enrolled patients with severe symptomatic aortic stenosis who underwent successful TAVR.

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Aortic valve Thrombosis Aortic Technology 52

American College of Cardiology

OCTOBER 28, 2024

The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).

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TAVR Stenosis Aortic Aortic valve 63

American College of Cardiology

SEPTEMBER 27, 2024

How does diffuse interstitial myocardial fibrosis, as observed on cardiac magnetic resonance (CMR), correlate with clinical outcomes in moderate and asymptomatic severe aortic stenosis (AS)?

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Stenosis Aortic Outcomes Article 60

American College of Cardiology

MAY 29, 2024

In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis.

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Aortic valve Aortic Stenosis Article 60

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

This concept should be applied when managing older patients with severe aortic stenosis. Although left ventricular wall hypertrophy is expected in patients with aortic stenosis, it should not be assumed that this is caused only by aortic stenosis.

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Stenosis Aortic TAVR Aortic valve 69

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

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Aortic valve Aortic Quality of Life TAVR 98

American College of Cardiology

MARCH 6, 2024

What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?

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JAMA Cardiology

MARCH 25, 2025

This Viewpoint discusses the use of aortic valve intervention vs watchful waiting for patients with asymptomatic aortic stenosis.

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Aortic valve Aortic Stenosis 44

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

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Aortic valve Aortic TAVR Peripheral Arterial Disease 98

American College of Cardiology

JULY 23, 2024

What is the association between plasma lipoprotein(a) [Lp(a)] concentrations and hemodynamic progression in patients with aortic stenosis?

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Stenosis Aortic valve Aortic Article 56

American College of Cardiology

APRIL 22, 2024

What is the 5-year incidence of valve reintervention after self-expanding CoreValve/Evolut transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR)?

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TAVR Aortic Aortic valve Stenosis 69

American College of Cardiology

JUNE 18, 2024

In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.

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Heart Failure Stenosis Aortic TAVR 58

Med Page Today

JANUARY 16, 2025

(MedPage Today) -- People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared particularly poorly in a large cohort study, which researchers said calls for awareness and timely treatment. Compared with AS alone.

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Stenosis Aortic Outcomes Research 59

Heart BMJ

FEBRUARY 26, 2025

In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.

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Aortic valve Aortic Stenosis 59

Cassling

JANUARY 9, 2025

EchoSolv, the groundbreaking AI platform developed by Echo IQ, is revolutionizing the detection of aortic stenosis. With its unparalleled access to extensive echocardiographic data and AI-driven analysis, EchoSolv empowers clinicians to identify aortic stenosis earlier and with greater accuracy.

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Heart Disease Stenosis Aortic Innovation 52

American College of Cardiology

NOVEMBER 20, 2024

Which genetic and cardiovascular risk factors are aortic stenosis (AS)-specific, and which could be shared between AS and with coronary artery disease (CAD)?

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Stenosis Aortic Coronary Artery Disease Risk Factors 53

American College of Cardiology

FEBRUARY 26, 2025

In this weeks View, Dr. Eagle looks at the potential exposure-dependent protective effect of SGLT2 inhibitors on aortic valve stenosis progression.

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Aortic valve Stenosis Aortic AFIB 63

The New England Journal of Medicine

MARCH 28, 2025

With the aging of the population, aortic stenosis affects a growing number of patients, with a prevalence of 12.4% have severe aortic stenosis.1 1 Aortic stenosis is generally well tolerated for a prolonged period of time, among persons who are at least 75 years of age, among whom 3.4%

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American College of Cardiology

SEPTEMBER 24, 2024

What are the clinical features and prognosis of patients with high-gradient (HG) aortic stenosis (AS) with a calculated aortic valve area (AVA) of >1.0

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Stenosis Aortic Aortic valve Article 50