DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Journal of the American Heart Association

JANUARY 12, 2024

Irradiation of 282 nm UV‐B but not 301 or 312 nm UV‐B significantly reduced the development of aortic root atherosclerotic plaques and plaque inflammation.

Atherosclerosis 45

Atherosclerosis Plaque Aortic Technology 45

EMS 12-Lead

APRIL 9, 2024

Sudden narrowing of a coronary artery due to ACS (plaque rupture with thrombosis and/or downstream showering of platelet-fibrin aggregates). The underlying etiology is either Type 1 or Type II ischemia, although sometimes there’s overlap of both. Type I ischemia. Type II ischemia.

Ischemia 116

Ischemia Stenosis Chest Pain Coronary Artery Disease 116

Dr. S. Venkatesan MD

DECEMBER 2, 2023

This has important clinical significance , as many successfully lysed STEMI patient might have minimal segments of dissection/deep plaque fissures. , Kim N Engl J Med 2020; 383:2358-2370 Next query What is the difference between plaque fissure and coronary arterial dissection? Is plaque fissure painful ?

SCAD 52

SCAD Plaque Angina Physiology 52

Journal of the American Heart Association

NOVEMBER 23, 2023

Mice lackingFxrandGpbar1−/−/Fxr−/−display hypotension and aortic inflammation, along with altered intestinal permeability that deteriorates with age, and severe dysbiosis, along with dysregulated bile acid synthesis. Vasomotor activities of aortic rings were altered byGpbar1andFxrgene ablation.

Aortic 40

Aortic Aneurysm Plaque Cholesterol 40

Circulation

NOVEMBER 11, 2024

Description of Case:A 64-year-old male with complex medical history, including infective endocarditis of the aortic valve requiring surgical replacement with a bioprosthetic valve and recurrent infective endocarditis of the bioprosthetic valve, presented with two hours of crushing chest pain and found to have ST elevations.

Aortic valve 40

Aortic valve TAVR Aortic Chest Pain 40

Cardiology Update

APRIL 9, 2024

SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aortic valve replacement (TAVR). The study concluded that among low-risk patients with severe aortic stenosis, TAVI is as effective as SAVR in terms of the composite outcome of death or stroke at 1 year.

Angina 52

Angina Myocardial Infarction Aortic valve Coronary Artery Disease 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

With its advantage of shape and stiffness buffering the kickback force with support of lesser curvature of aortic arch, BGCs were navigated to the appropriate position without touching to the plaques.ResultsThe technique were applied in 5 cases (age: 73‐85 years old, 4 males, 4 left‐sided lesions) among the 37 consequent CAS cases.

Stent 40

Stent Stents Plaque Aortic 40

Dr. Smith's ECG Blog

OCTOBER 20, 2024

There are multiple possible clinical situations that could account for diffuse subendocardial ischemia that is not due to ACS and plaque rupture. Post PCI an intra-aortic balloon pump (IABP) was placed and a combination of norepinephrine and dobutamine was needed to maintain perfusion pressures.

Cardiogenic Shock 129

Cardiogenic Shock Ischemia Chest Pain Cardiac Arrest 129

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

A 69‐year‐old woman with a history of lung cancer, hypertension, chronic tobacco use, atherosclerosis, and known calcified plaque at the left carotid bifurcation on dual antiplatelet therapy presented with acute onset of expressive aphasia and right hemiparesis due to acute left CCAO.

Outcomes 40

Outcomes Chest Pain Coronary Artery Disease Aortic 40

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

EMS 12-Lead

JULY 24, 2023

Category 1 : Sudden narrowing of a coronary artery due to ACS (plaque rupture with thrombosis and/or downstream showering of platelet-fibrin aggregates. elevated BP), but rather directly correlated with coronary obstruction (due to plaque rupture and thrombosis) and, potentially, stymied TIMI flow. Aortic Stenosis f.

Angina 52

Angina Ischemia Coronary Angiogram Stenosis 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The phantom includes the aortic arch, all supraoptic cervical arteries and a complete circle of Willis up to the M2‐MCA, A2‐ACA and P2‐PCA segments. The phantom includes the aortic arch, all supraoptic cervical arteries and a complete circle of Willis up to the M2‐MCA, A2‐ACA and P2‐PCA segments.

Stenosis 40

Stenosis Angioplasty Anatomy Plaque 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, CTA head and neck 4 days later demonstrated 90 percent stenosis of the mid left V2 at the C3‐4 level and a 75‐90 percent stenosis of the left mid V2 segment at the C5‐6 level (hard and soft plaque in these areas). He was switched from DAPT to aspirin and warfarin because he was considered a “DAPT failure.”

Stenosis 40

Stenosis Peripheral Arterial Disease Pacemaker Atherosclerosis 40

Dr. Smith's ECG Blog

NOVEMBER 4, 2022

2 cases of Aortic Stenosis: Diffuse Subendocardial Ischemia on the ECG. Widespread ST-depression with reciprocal aVR ST-elevation can be cause by: Heart rate related: tachyarrhythmia (e.g., Initial blood work showed the following: metabolic acidosis on VBG with a lactate of 7.1; Left main? 3-vessel disease?

Ischemia 52

Ischemia STEMI Stenosis Chest Pain 52

Dr. Smith's ECG Blog

JANUARY 9, 2023

CT angiogram chest: no aortic dissection or pulmonary embolism. Only after her troponin peaked at 500,000 ng/L did she get her angiogram, which showed a 100% left main occlusion due to ruptured plaque. No further troponins were measured. Serial chest xrays: progressive bilateral pulmonary edema. Diagnostic of Massive OMI.

Chest Pain 52

Chest Pain Aneurysm STEMI Thrombosis 52

Dr. Smith's ECG Blog

MAY 10, 2023

LAD plaque with 0-25 percent stenosis. No signs for aortic dissection or pulmonary embolus. --"Results were discussed with the ordering physician. Now, with elevated troponins, Wellens' syndrome is likely. A CT Coronary angiogram was ordered. Here are the results: --Minimally obstructive coronary artery disease. --LAD

Coronary Angiogram 52

Coronary Angiogram Chest Pain Stenosis STEMI 52

Circulation

DECEMBER 15, 2023

Mechanistically, HEG1 knockdown prevented s-flow–induced KLF2/4 (Krüppel-like factor 2/4) expression by regulating its intracellular binding partner KRIT1 (Krev interaction trapped protein 1) and the MEKK3-MEK5-ERK5-MEF2 pathway in human aortic endothelial cells.

Atherosclerosis 45

Atherosclerosis Diet Aortic Plaque 45

Dr. Smith's ECG Blog

DECEMBER 16, 2024

This was ruptured plaque with thrombus. Important: It is exceedingly rare for an anterior STEMI to be due to Aortic Dissection. Here it is: Type A Aortic Dissection Why was the troponin so elevated? of STEMI are due to Aortic Dissection. And almost all of them could be detected by bedside ultrasound. This is easy to see.

Chest Pain 105

Chest Pain Aortic STEMI Ultrasound 105

Dr. S. Venkatesan MD

JANUARY 1, 2025

Top 10 Clinical Trials Preventive PCI on Stenosis With Functionally Insignificant Vulnerable Plaque PREVENT (ACC.24) Top 10 Clinical Trials Preventive PCI on Stenosis With Functionally Insignificant Vulnerable Plaque PREVENT (ACC.24) 24) Microaxial Flow Pump in Infarct-Related Cardiogenic Shock DanGer Shock (ACC.24)

Cardiogenic Shock 59

Cardiogenic Shock Plaque Academic Bicuspid/Mitral 59

Cardiometabolic Health Congress

NOVEMBER 14, 2024

High Lp(a) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD), aortic stenosis, and all-cause mortality. Elevated Lp(a) is associated with complex, difficult-to-treat atherosclerotic lesions and fast-progressing plaques.

CME 103

CME Obesity Heart Failure Biomarkers 103