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Functional assessment of coronary artery disease in patients with severe aortic stenosis: a review

Heart BMJ

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). A better understanding of how we assess and interpret coronary physiology in these patients is required to optimise treatment pathways.

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Obstructive sleep apnea may increase risk of abdominal aortic aneurysms

Medical Xpress - Cardiology

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

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Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac Remodeling

Journal of the American Heart Association

MC1R recessive yellow mice showed blunted hypertrophic response to transverse aortic constrictioninduced pressure overload and exercise training. Mice were phenotyped for cardiac structure and function by echocardiography, histology, and quantitative PCR analysis.

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Modern management of ruptured abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

Ruptured abdominal aortic aneurysms (rAAA) remain one of the most clinically challenging and technically complex emergencies in contemporary vascular surgery practice. Moreover, evolution in pre- and post-operative physiologic resuscitation has also contributed to observed improvements in rAAA outcomes.

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A curious case of LVOT VTI Alternans with an Intra-Aortic Balloon Pump: Physiology in Action

The American Journal of Cardiology

Publication date: Available online 6 March 2024 Source: The American Journal of Cardiology Author(s): Sumana Vardhan, Jonathan D.

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Abstract 4139822: Adipocyte TRPM7 promotes aortic dissection by accelerating SMC phenotype switching

Circulation

Digging into and unravelling the pathogenesis of AD will aid in exploring novel therapeutics for AD.The major characteristics of AD is degeneration of aortic wall architecture. Different segments of mouse aorta were subjected to EVG staining to examine the aortic wall architecture.Real-time quantitative PCR (qPCR).

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Recent advances of myotubularin-related (MTMR) protein family in cardiovascular diseases

Frontiers in Cardiovascular Medicine

Based on the ability of modulating the levels of these PIPs, MTMRs exert physiological functions such as vesicle trafficking, cell proliferation, differentiation, necrosis, cytoskeleton, and cell migration. This review summarizes the functions of MTMRs and highlights their pathophysiological roles in cardiovascular diseases.