American College of Cardiology

SEPTEMBER 27, 2024

How does diffuse interstitial myocardial fibrosis, as observed on cardiac magnetic resonance (CMR), correlate with clinical outcomes in moderate and asymptomatic severe aortic stenosis (AS)?

Stenosis 60

Stenosis Aortic Outcomes Article 60

Journal of the American Heart Association

JANUARY 16, 2025

BackgroundThe coexistence of transthyretin cardiac amyloidosis (ATTRCA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear. Ad hoc subanalyses were conducted in patients with aortic valve replacement at first diagnosis (surrogate for severe AS). 95% CI, 1.11.4];P<0.0001)

Aortic 73

Aortic Aortic valve Stenosis Outcomes 73

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

Open Heart

JANUARY 8, 2024

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.

Aortic valve 98

Aortic valve Aortic Preserved Ejection Fraction Stenosis 98

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

Aortic valve 98

Aortic valve Cancer Aortic TAVR 98

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

Cardiology Update

FEBRUARY 26, 2024

Transcatheter aortic valve replacement (TAVR) is the standard treatment for severe aortic stenosis, but post-TAVR leaflet thrombus, identified by hypoattenuated leaflet thickening (HALT), poses potential risks like cerebral thromboembolic events. had thrombus at any aortic valve complex. Specifically, 14.2%

TAVR 122

TAVR Aortic valve Outcomes Aortic 122

DAIC

MARCH 4, 2025

Early detection through regular heart check-ups, including listening for murmurs, can lead to timely treatment and improved outcomes. The earlier we catch it, the more treatment options we have, and the better the outcome for the patient. AS occurs when the aortic valve narrows, restricting blood flow from the heart to the body.

Heart Valves 52

Heart Valves Aortic valve Aortic Stenosis 52

Med Page Today

JANUARY 16, 2025

(MedPage Today) -- People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared particularly poorly in a large cohort study, which researchers said calls for awareness and timely treatment. Compared with AS alone.

Stenosis 59

Stenosis Aortic Outcomes Research 59

DAIC

MAY 15, 2024

Getty Images milla1cf Wed, 05/15/2024 - 19:10 May 15, 2024 — A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart— transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR). 1.11, p=0.70) with similar long-term mortality risks.

Aortic valve 105

Aortic valve TAVR Outcomes Aortic 105

American College of Cardiology

MARCH 6, 2024

What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?

TAVR 60

TAVR Aortic Stenosis Aortic valve 60

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

This concept should be applied when managing older patients with severe aortic stenosis. Although left ventricular wall hypertrophy is expected in patients with aortic stenosis, it should not be assumed that this is caused only by aortic stenosis.

Stenosis 69

Stenosis Aortic TAVR Aortic valve 69

American College of Cardiology

FEBRUARY 18, 2025

The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.

Stenosis 61

Stenosis Aortic Aortic valve TAVR 61

American College of Cardiology

JUNE 18, 2024

In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.

Heart Failure 58

Heart Failure Stenosis Aortic TAVR 58

Open Heart

FEBRUARY 17, 2025

We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups. Outcomes did not vary by pandemic birth era according to social characteristics.

Congenital Heart Disease 52

Congenital Heart Disease Congenital Heart Disease Outcomes 52

Open Heart

MAY 31, 2022

Objective To use echocardiographic and clinical features to develop an explainable clinical risk prediction model in patients with aortic stenosis (AS), including those with low-gradient AS (LGAS), using machine learning (ML). for the combined outcome of mortality/AVR. p<0.05).

Stenosis 52

Stenosis Aortic Outcomes Aortic valve 52

Circulation: Cardiovascular Interventions

JANUARY 22, 2025

Some patients with aortic stenosis may require multiple valve interventions in their lifetime, and choosing transcatheter aortic valve replacement (TAVR) as the initial intervention may be appealing to many. Circulation: Cardiovascular Interventions, Ahead of Print.

TAVR 73

TAVR Aortic valve Aortic Stenosis 73

Journal of Cardiothoracic Surgery

APRIL 19, 2024

Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnit.

Aortic valve 52

Aortic valve Aortic Stenosis Outcomes 52

Frontiers in Cardiovascular Medicine

JANUARY 2, 2024

Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation.

Aortic valve 64

Aortic valve Bicuspid/Mitral Aortic Outcomes 64

American College of Cardiology

JUNE 11, 2024

What is the change in incidence, clinical presentation, treatment, and outcome for quantitatively defined severe aortic stenosis (AS) over the last 20 years in a population-based community?

Stenosis 40

Stenosis Aortic Outcomes Article 40

Journal of the American Heart Association

MARCH 13, 2025

BackgroundLp(a) (lipoprotein(a)) is an independent risk factor for calcific aortic valve stenosis (CAVS). Whether patients with CAVS and high Lp(a) levels are at higher risk of valvular or cardiovascular events is unknown.

Aortic valve 45

Aortic valve Coronary Artery Bypass Graft Stenosis Aortic 45

DAIC

MARCH 10, 2025

Among Medtronic's Structural Heart and Aortic key data milestones,Dr. The presentation addressed the two-year results of the SMall Annuli Randomized To Evolut or SAPIENTrial, which evaluated a valve performance in individuals with aortic stenosiswith small aortic annulusin patients treated with either EvolutTAVR platform or SAPIENplatform.

Blood Pressure 52

Blood Pressure Aortic Medicare Hypertension 52

DAIC

MARCH 14, 2025

Washington Convention Center in Washington, DC.

TAVR 52

TAVR Aortic valve Peripheral Arterial Disease Embolism 52

JAMA Cardiology

NOVEMBER 5, 2024

Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.

Atherosclerosis 48

Atherosclerosis Aortic Stenosis Aortic valve 48

Circulation: Cardiovascular Imaging

MARCH 21, 2025

BACKGROUND:Patients with paradoxical low-flow, low-gradient severe aortic stenosis exhibit low transvalvular flow rate (Q), while maintaining preserved left ventricular ejection fraction. Over a follow-up of up to 5 years, severe MR correlated with higher all-cause mortality (P=0.02) and aortic valve replacement rates (P=0.012).

Stenosis 40

Stenosis Aortic Aortic valve Bicuspid/Mitral 40

American College of Cardiology

MARCH 18, 2024

What is the prevalence and what are the survival outcomes of patients with discordant high-gradient aortic stenosis (DHG-AS; defined as mean gradient [MG] ≥40 mm Hg and effective orifice area [EOA] >1.0

Outcomes 74

Outcomes Stenosis Aortic Article 74

American College of Cardiology

MARCH 27, 2024

In this week’s View, Dr. Eagle looks at sacubitril/valsartan in patients hospitalized with decompensated heart failure, then examines the prevalence and outcomes of patients with discordant high gradient aortic stenosis.

Heart Failure 58

Heart Failure Stenosis Aortic Tricuspid 58

Circulation: Cardiovascular Interventions

MARCH 26, 2025

BACKGROUND:Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access. At 30 days, the SAVR group showed a higher rate of the primary composite outcome compared with the TC-TAVR group (12.6% andP=0.001, respectively).

Aortic valve 40

Aortic valve Aortic Stenosis TAVR 40

Open Heart

MAY 12, 2023

Objective To evaluate whether transcatheter or surgical aortic valve replacement (TAVR or SAVR) affects clinical and haemodynamic outcomes in symptomatic patients with moderately-severe aortic stenosis (AS). <aortic valve area (AVA)<1.5 <aortic valve area (AVA)<1.5 cm 2 , 3.0<peak

Aortic valve 52

Aortic valve Aortic Stenosis TAVR 52

American College of Cardiology

FEBRUARY 12, 2024

The goal of the NOTION trial was to compare outcomes after transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in unselected patients with severe degenerative aortic stenosis.

Aortic valve 56

Aortic valve Aortic TAVR Stenosis 56

Medical Xpress - Cardiology

MAY 15, 2024

A new study demonstrates parity between a minimally invasive procedure to replace the aortic valve in the heart—transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR).

Aortic valve 45

Aortic valve Aortic TAVR Stenosis 45

Coronary Artery Disease Journal

MAY 13, 2024

Objective To investigate the impact of prior coronary artery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. 23), which was not associated with better/worse clinical outcomes in patients with prior CABG.

Coronary Artery Bypass Graft 40

Coronary Artery Bypass Graft Aortic valve Aortic Stenosis 40

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. Journal of the American Heart Association, Ahead of Print. In multivariate analysis, low CCDR (hazard ratio, 2.21 [95% CI, 0.99–4.92],P=0.04)

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

Circulation

OCTOBER 23, 2024

BACKGROUND:This study aimed to compare the incidence and prognostic implications of new-onset conduction disturbances after surgical aortic valve replacement (SAVR) in patients with bicuspid aortic valve (BAV) aortic stenosis (AS) versus patients with tricuspid aortic valve (TAV) AS (ie, BAV-AS and TAV-AS, respectively).

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

Circulation: Cardiovascular Interventions

OCTOBER 17, 2023

BACKGROUND:Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce. Ascending aortic diameter was the single predictor of 1-year mortality in type 0 bicuspid patients (hazard ratio, 1.59 [95% CI, 1.03–2.44];P=0.035). Poverall=0.765; 1 year: 1.4%

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

DAIC

APRIL 23, 2024

This next-generation surgical aortic tissue valve is designed to facilitate ease of use at implant and lifetime patient management. It’s an excellent choice for cardiac surgeons and their patients seeking an aortic valve solution that can be fit for the future, right from the start. 5 Verbelen T, Roussel JC, Cathenis K, et al.,

Aortic valve 111

Aortic valve Aortic Innovation Cardiothoracic 111

DAIC

JUNE 7, 2024

milla1cf Fri, 06/07/2024 - 14:50 June 7, 2024 — Medtronic today announced new data from the CoreValve Evolut Clinical Program , reinforcing the positive performance of the Evolut transcatheter aortic valve replacement (TAVR) System compared to surgical aortic valve replacement (SAVR) and other TAVR valves. Evolut vs. 10.6%

TAVR 111

TAVR Aortic valve Aortic Stenosis 111