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The study, leveraging data from the STS Adult Cardiac Surgery Database (ACSD), offers the most comprehensive analysis to date of prosthetic valve outcomes, encompassing over 100,000 patients. The study addressed a critical question in cardiac surgery: how age and valve type influence outcomes for patients undergoing surgical AVR.
Background Acute aortic dissection (AD) in pregnancy poses a lethal risk to both mother and fetus. This study aimed to investigate clinical features, outcomes and optimal management strategies for pregnancy-related AD. Patient characteristics, management strategies and short-term outcomes were analysed. to 33.09); p=0.001).
tim.hodson Mon, 03/31/2025 - 15:39 March 30, 2025 Medtronic has announced late-breaking data on five-year outcomes from the Evolut Low Risk Trial. Two-Year Outcomes of the Five-Year SMART Trial, presented at CRT 2025. Reardon, M.D., Additional findings at five years include: Numerically lower rate of cardiovascular mortality (7.2%
The sociodemographic characteristics of patients undergoing intervention for aortic stenosis (AS) in England, and the impact of COVID-19, is unknown. Background Health inequalities in cardiovascular care have been identified in the UK.
Implantation of an intra-aortic balloon pump (IABP) did not improve 60-day survival or bridge to heart replacement (HRT) therapies in patients with heart failure-cardiogenic shock (HF-CS) compared to standard care, according to a study presented during a Featured Clinical Research session at ACC.25
The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. Severe SVD was defined by specific criteria.
In an era of rapidly expanding use of transcatheter aortic valve implantation (TAVI), the management of patients with bicuspid aortic valve (BAV) disease is far less well established than in those with trileaflet anatomy.
Background Heart failure with preserved ejection fraction is a recognised outcome in patients with myocardial infarction, although heart failure with reduced ejection fraction is more common. to 1.97), and a similar association was observed for aortic valve peak velocity (HR: 1.37, 95% CI 1.19 m/s had a 2.10-fold
ObjectivesRegistered, prospective, multicenter study of the short-term clinical outcomes of a novel transcatheter aortic valve system (Xcor system, Saint Medical Technology, Inc., Procedural, in-hospital, and follow-up clinical outcomes were evaluated after procedures.ResultsThe average age of the 130 patients was 71.24.4
Transcatheter aortic valve replacement (TAVR) has become a leading treatment for aortic stenosis, but managing thromboembolic and bleeding risks post-procedure remains challenging. This review examines current evidence on antithrombotic therapy after TAVR.
Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis.
Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients.
Shettys team followed 252 patients who underwent the Ross procedure, a heart valve replacement operation commonly used to treat younger patients with severe aortic valve disease. We wanted to examine our outcomes, and we were pleasantly surprised to find that the freedom from re-intervention was 91% at 10 years and 87% at 20 years.
Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesispatient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement.
This study aimed to evaluate the early and mid-term outcomes of transcatheter closure using a double-disc occluder device in a single-center Vietnamese cohort.MethodA prospective descriptive study was conducted at Hanoi Heart Hospital, Vietnam. Data were analyzed using SPSS 20.0.ResultsThe
Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.
IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV). Forty-seven received SEVs using COL, and 50 with CON techniques.
Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.
Transcatheter aortic valve replacement (TAVR) is the standard treatment for severe aortic stenosis, but post-TAVR leaflet thrombus, identified by hypoattenuated leaflet thickening (HALT), poses potential risks like cerebral thromboembolic events. had thrombus at any aortic valve complex. Specifically, 14.2%
Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).
BackgroundAbdominal aortic calcification (AAC), an early indicator of abdominal aortic wall atherosclerosis, is a marker of subclinical atherosclerosis and a predictive factor for vascular-associated morbidity and mortality. These outcomes are driven by inflammatory processes.
(MedPage Today) -- LOS ANGELES -- Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry.
PurposeAbdominal aortic calcification (AAC) is related to inflammation and nutritional status. This research seeks to investigate the correlation of NPS with severe abdominal aortic calcification (SAAC).MethodsThe
Getty Images milla1cf Wed, 05/15/2024 - 19:10 May 15, 2024 — A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart— transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR). 1.11, p=0.70) with similar long-term mortality risks.
The optimal management of concomitant chronic obstructive coronary artery disease (CAD) in transcatheter aortic valve replacement (TAVR) recipients remains a debated topic. Major outcomes included procedural all-cause mortality and complications, major adverse cardiovascular events, and post-TAVR unplanned coronary revascularization.
This study aimed to explore whether metabolic syndrome (MetS) and its components are associated with poor outcomes in patients with acute type A aortic dissection (ATAAD) after surgery.
BackgroundThe coexistence of transthyretin cardiac amyloidosis (ATTRCA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear. Ad hoc subanalyses were conducted in patients with aortic valve replacement at first diagnosis (surrogate for severe AS). 95% CI, 1.11.4];P<0.0001)
How does diffuse interstitial myocardial fibrosis, as observed on cardiac magnetic resonance (CMR), correlate with clinical outcomes in moderate and asymptomatic severe aortic stenosis (AS)?
We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups. Outcomes did not vary by pandemic birth era according to social characteristics.
Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.
Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation.
Background Redo sternotomy aortic root surgery is technically demanding, and the evidence on outcomes is mostly from retrospective, small sample, single-centre studies. We report the trend, early clinical results and outcome predictors of redo aortic root replacement over 20 years in the United Kingdom.
Early detection through regular heart check-ups, including listening for murmurs, can lead to timely treatment and improved outcomes. The earlier we catch it, the more treatment options we have, and the better the outcome for the patient. AS occurs when the aortic valve narrows, restricting blood flow from the heart to the body.
Photo courtesy of Mount Sinai Health System milla1cf Thu, 02/22/2024 - 13:47 February 22, 2024 — Ismail El-Hamamsy , MD, PhD, Director of Aortic Surgery for the Mount Sinai Health System and the Mount Sinai Randall B. The aortic valve controls blood flow from the heart into the aorta, the main artery that feeds blood to most of the body.
The primary outcome was survival at the follow-up evaluation. More homogeneous and adequately powered cohorts are needed to better understand the impact of VAD support on posttransplant outcomes. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.
This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).
BACKGROUND:Despite reported racial disparities between Black and White adults in short-term outcomes after abdominal aortic aneurysmal intervention, there is a paucity of literature aimed at understanding long-term disparities. The cumulative incidence of the primary outcome was 72.9% (95% CI, 71.8%73.9%)
What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?
BackgroundThe left subclavian artery (LSA) can be intentionally covered by a stent graft to acquire adequate landing zones for a proximal entry tear near the LSA during thoracic endovascular aortic repair (TEVAR). The Castor single-branched stent graft is designed to treat type B aortic dissection (TBAD) to retain the LSA during TEVAR.
Aortic coarctation (AoC) is a common congenital heart defect, affecting 5%8% of patients with structural congenital anomalies. In these patients, hypertension is associated to renin-angiotensin system activation, residual aortic arch abnormalities, and impaired aortic elasticity.
2 Therefore, early identification of HF in high-risk populations, particularly post-MI, is essential for improving outcomes. Heart failure (HF) is one of the significant complications in patients with myocardial infarction (MI), leading to increased risk for cardiovascular morbidity and mortality.
(MedPage Today) -- People with transthyretin cardiac amyloidosis (ATTR-CA) on top of aortic stenosis (AS) fared particularly poorly in a large cohort study, which researchers said calls for awareness and timely treatment. Compared with AS alone.
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