Aortic and Kidney Disease - Cardiovascular Update

Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification

Circulation

FEBRUARY 13, 2024

The role of 4-hydroxynonenal (4-HNE), which is the most abundant stable product of lipid peroxidation, in vascular calcification has been poorly investigated.METHODS:Serum was collected from patients with chronic kidney disease and controls, and the levels of 4-HNE and 8-iso-prostaglandin F2α were measured.

Coronary Artery Disease

Coronary Artery Disease Kidney Disease Aortic Plaque

Protruding Aortic Plaque and Coronary Plaque Vulnerability

Journal of the American Heart Association

JANUARY 9, 2024

BackgroundProtruding aortic plaque is known to be associated with an increased risk for future cardiac and cerebrovascular events. Coronary plaque characteristics were compared to evaluate coronary plaque vulnerability in patients with protruding aortic plaque on computed tomography angiography.

Plaque

Plaque Aortic Myocardial Infarction Kidney Disease

Association of body roundness index with abdominal aortic calcification among middle aged and elderly population: findings from NHANES

Frontiers in Cardiovascular Medicine

OCTOBER 9, 2024

Additionally, restricted cubic splines (RCS) analysis was also employed.ResultsWe found that those with AAC were significantly older and had a higher prevalence of smoking and chronic kidney disease (CKD) prevalence compared to those without AAC.

Aortic

Aortic Obesity Kidney Disease Public Health

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Development and validation of LCMM prediction algorithms to estimate recovery pattern of postoperative AKI in type A aortic dissection: a retrospective study

Frontiers in Cardiovascular Medicine

APRIL 18, 2024

Binary logistic regression identified five critical determinants regarding poor renal recovery, including chronic kidney disease (CKD) history, renal hypoperfusion, circulation arrest time, intraoperative urine, and myoglobin. Among the PO-AKI cohort, the LCMM identified two distinct eGFR trajectories: early recovery (ER-AKI, 51.8%

Aortic

Aortic ICU Kidney Disease Circulation

Cardiovascular Outcomes of Transcatheter Aortic Valve Implantation in Patients With Chronic Kidney Disease in Octogenarian Population

The American Journal of Cardiology

DECEMBER 13, 2023

Publication date: 15 January 2024 Source: The American Journal of Cardiology, Volume 211 Author(s): David Song, Yasar Sattar, Mohammed Faisaluddin, Usama Talib, Neel Patel, Izza Shahid, Amro Taha, Fnu Raheela, Prasana Sengodon, Maria Riasat, Vaibhav Shah, Karthik Gonuguntla, Mahboob Alam, Islam Elgendy, Ramesh Daggubati, M. Chadi Alraies

Aortic valve

Aortic valve Kidney Disease Aortic Outcomes

Why the sudden shock after a few days of malaise?

Dr. Smith's ECG Blog

SEPTEMBER 5, 2024

Left ventricular afterload reduction is essential to decrease the trans-se ptal pressure gradient and thus decrease shunt volume, making a larger proportion of the blood flow from the left ventricle through the aortic valve. Surgical repair of the VSR was eventually done.

Cardiogenic Shock

Cardiogenic Shock Chest Pain Pericarditis Myocardial Infarction

Prediction of In?Hospital Mortality for Ischemic Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation

Journal of the American Heart Association

FEBRUARY 16, 2024

Fifteen predictors were included for model development: age, diastolic blood pressure, hypertension, chronic kidney disease, peak lactic acid, serum creatinine, lowest left ventricular ejection fraction, vasoactive inotropic score, shock to extracorporeal membrane oxygenation insertion time, extracorporeal cardiopulmonary resuscitation, use of intra‐aortic (..)

Cardiogenic Shock

Cardiogenic Shock Hospital Myocardial Infarction Kidney Disease

The failing heart and kidney: improving prevention and treatment

The British Journal of Cardiology

MARCH 7, 2024

The Cardiorenal Forum’s recent 18 th Annual Scientific meeting looked at the latest updates in the failing heart and kidney.

Diabetes

Diabetes Kidney Disease Stenosis Aortic

Temporal trends of aortic stenosis and comorbid chronic kidney disease in the province of Quebec, Canada

Open Heart

JUNE 16, 2022

Objective To investigate temporal trends of chronic kidney disease (CKD) among patients with incident aortic stenosis (AS) and to compare these trends with that of a matched control population.

Kidney Disease

Kidney Disease Stenosis Aortic Outpatient

Incident cardiovascular, renal, metabolic diseases and death in individuals identified for risk-guided atrial fibrillation screening: a nationwide cohort study

Open Heart

JULY 10, 2023

Higher-predicted risk, compared with lower-predicted risk, was associated with incident chronic kidney disease (cumulative incidence per 1000 persons at 10 years 245.2; to 5.22; 4.32), peripheral vascular disease (44.6; to 6.98; 4.28), valvular heart disease (37.8; to 6.85; 4.54), aortic stenosis (18.7; 2.05, 2.00

Atrial Fibrillation

Atrial Fibrillation Myocardial Infarction Kidney Disease Innovation

Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

Cardiovascular Disease

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease

Diabetes is associated with a higher incidence of short-term mortality risk and readmission in patients who undergo surgical but not transcatheter aortic valve replacement

Open Heart

JANUARY 11, 2025

Background Transcatheter aortic valve replacement (TAVR) is increasingly used for aortic valve replacement instead of surgical aortic valve replacement (sAVR). Results The study included 110 135 patients who underwent aortic valve replacement. Diabetes was present in 36.4% of TAVR patients and 29.1% of sAVR patients.

Aortic valve

Aortic valve TAVR Diabetes Aortic

5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC)

Cardiometabolic Health Congress

NOVEMBER 14, 2024

Additionally, 10% of the global population suffers from chronic kidney disease , with diabetes and hypertension as significant risk factors. Disparities in care are also concerning, with diagnosed cardiometabolic diseases varying up to twofold among different racial and ethnic groups. In the U.S.,

CME

CME Obesity Heart Failure Biomarkers

Chest pain followed by 6 days of increasing dyspnea -- what happened?

Dr. Smith's ECG Blog

FEBRUARY 26, 2025

Larger shunt volume means less blood exiting the left ventricle through the aortic valve and lower cardiac output. Mechanical complications such as free wall rupture, VSR and papillary muscle rupture is more likely to occur in patients who are older, female, hypertensive, have chronic kidney disease, and have no prior history of smoking.

Chest Pain

Chest Pain Pericarditis Myocardial Infarction Dementia

Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification

Protruding Aortic Plaque and Coronary Plaque Vulnerability

Association of body roundness index with abdominal aortic calcification among middle aged and elderly population: findings from NHANES

Webinars

Development and validation of LCMM prediction algorithms to estimate recovery pattern of postoperative AKI in type A aortic dissection: a retrospective study

Cardiovascular Outcomes of Transcatheter Aortic Valve Implantation in Patients With Chronic Kidney Disease in Octogenarian Population

Why the sudden shock after a few days of malaise?

Prediction of In?Hospital Mortality for Ischemic Cardiogenic Shock Requiring Venoarterial Extracorporeal Membrane Oxygenation

The failing heart and kidney: improving prevention and treatment

Temporal trends of aortic stenosis and comorbid chronic kidney disease in the province of Quebec, Canada

Incident cardiovascular, renal, metabolic diseases and death in individuals identified for risk-guided atrial fibrillation screening: a nationwide cohort study

Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

Diabetes is associated with a higher incidence of short-term mortality risk and readmission in patients who undergo surgical but not transcatheter aortic valve replacement

5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC)

Chest pain followed by 6 days of increasing dyspnea -- what happened?

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