article thumbnail

The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experience”

Frontiers in Cardiovascular Medicine

IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.

article thumbnail

An explainable machine learning approach using contemporary UNOS data to identify patients who fail to bridge to heart transplantation

Frontiers in Cardiovascular Medicine

BackgroundThe use of Intra-aortic Balloon Pump (IABP) and Impella devices as a bridge to heart transplantation (HTx) has increased significantly in recent times. or IABP.

article thumbnail

Single-cell RNA sequencing and ATAC sequencing identify novel biomarkers for bicuspid aortic valve-associated thoracic aortic aneurysm

Frontiers in Cardiovascular Medicine

IntroductionBicuspid aortic valve (BAV) is the most prevalent congenital cardiovascular defect and known to cause thoracic aortic aneurysms (TAAs). TAA-related changes were evaluated by comparing the proportion of each cell type and gene expression profiles between TAA and control tissues.

article thumbnail

Early left atrial venting versus conventional treatment for left ventricular decompression during venoarterial extracorporeal membrane oxygenation support: The EVOLVE?ECMO randomized clinical trial

European Journal of Heart Failure

Patients with significant pulmonary oedema or aortic valve (AV) closure during venoarterial extracorporeal membrane oxygenation (VA-ECMO) were randomized to early left ventricular (LV) unloading or conventional strategy groups (1:1). CV, cardiovascular; HT, heart transplantation; ICU, intensive care unit; LVAD, left ventricular assist device.

article thumbnail

The Thoracic Surgery Foundation Awards Inaugural International Fellowships

Society of Thoracic Surgeons - Technology

With her fellowship, Dr. Fiedler plans to learn skills and administrative approaches that will help her expand the heart transplant program at UW-Madison, where she currently serves as associate director of heart transplantation and mechanical circulatory support.

article thumbnail

Latest Medical News: Partial Heart Transplant of an Infant

Wellnest

Introduction: Wellnest brings you , the latest medical news where an infant successfully received a partial heart transplant! In a remarkable leap forward for pediatric cardiac care, a groundbreaking partial heart transplant procedure has emerged as a beacon of hope for infants facing severe congenital heart conditions.

article thumbnail

Highlights of ACC 2024

Cardiology Update

SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aortic valve replacement (TAVR). The study concluded that among low-risk patients with severe aortic stenosis, TAVI is as effective as SAVR in terms of the composite outcome of death or stroke at 1 year.

Angina 52