American College of Cardiology

JUNE 18, 2024

In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.

Heart Failure 53

Heart Failure Stenosis Aortic TAVR 53

Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. Early primary-graft-failure was 10% in group 1 and 13% in group 2.

Heart Transplant 52

Heart Transplant Transplant Pediatrics Heart Failure 52

Medical Xpress - Cardiology

OCTOBER 29, 2024

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

Aortic valve 45

Aortic valve Aortic Heart Failure Stenosis 45

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

American College of Cardiology

DECEMBER 17, 2024

The following are key points to remember from a review on aortic stenosis (AS), heart failure (HF), and aortic valve replacement (AVR).

Aortic valve 40

Aortic valve Heart Failure Aortic Stenosis 40

American College of Cardiology

OCTOBER 28, 2024

The goal of the TAVR UNLOAD trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with chronic systolic heart failure and moderate aortic stenosis (stage B aortic stenosis).

Aortic valve 46

Aortic valve Heart Failure Aortic TAVR 46

American College of Cardiology

MARCH 31, 2025

The goal of the Altshock-2 trial was to evaluate the effect of early intra-aortic balloon pump (IABP) use vs. standard care on 60-day survival or successful bridging to heart replacement therapies (HRT) in patients with heart failurecardiogenic shock (HF-CS).

Cardiogenic Shock 59

Cardiogenic Shock Aortic Heart Failure Article 59

Frontiers in Cardiovascular Medicine

MARCH 28, 2025

All statistical analyses were rigorously executed in R software.ResultsOur findings identified causal relationships between 15 metabolites and cardiovascular disease.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Aneurysm Heart Failure 52

European Journal of Heart Failure

FEBRUARY 26, 2025

Proposed approach for clinical management and therapeutic optimization in patients with heart failure with reduced ejection fraction and low blood pressure. Low blood pressure with major or mild symptoms. **SBP SBP <80mmHg or symptomatic low BP or asymptomatic low BP.

Blood Pressure 58

Blood Pressure Heart Failure Aortic valve TAVR 58

European Journal of Heart Failure

JANUARY 31, 2024

TAVR in heart failure. ABSTRACT Patients with severe aortic stenosis (AS) may develop heart failure (HF), the presence of which has traditionally been deemed as a final stage in AS progression with poor outcomes.

Aortic valve 40

Aortic valve Heart Failure Aortic TAVR 40

American College of Cardiology

MARCH 27, 2024

In this week’s View, Dr. Eagle looks at sacubitril/valsartan in patients hospitalized with decompensated heart failure, then examines the prevalence and outcomes of patients with discordant high gradient aortic stenosis.

Heart Failure 53

Heart Failure Stenosis Aortic Tricuspid 53

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

Background Closure of paravalvular leak (PVL) regurgitation after self-expandable (SE) transcatheter aortic valve implantation (TAVI) may be more challenging than after balloon-expandable (BE) valve implantation. The patient was deemed to be at prohibitive surgical risk and a catheter-based PVL closure procedure was planned.

Aortic valve 111

Aortic valve Aortic Atrial Fibrillation Heart Failure 111

Frontiers in Cardiovascular Medicine

FEBRUARY 29, 2024

Background High pulse pressure (PP) and aortic root diameter (AoD) are hallmarks of arterial stiffness or vascular aging and they are considered as risk factors for age-related cardiovascular disease, including heart failure (HF). However, the relationship between PP and AoD in patients with heart failure (HF) is uncertain.

Heart Failure 53

Heart Failure Aortic BMI Risk Factors 53

Heart BMJ

JULY 10, 2024

Clinical introduction A woman in her 60s with non-obstructive coronary artery disease, aortic valve replacement and aortic arch repair, chronic diastolic heart failure and paroxysmal atrial fibrillation (AF) and flutter (AFL), presented with 3 days of sustained palpitations that felt similar to prior episodes of AF/AFL.

Tachycardia 102

Tachycardia Aortic valve Coronary Artery Disease Atrial Fibrillation 102

Med Page Today

MARCH 29, 2025

(MedPage Today) -- CHICAGO -- Dapagliflozin (Farxiga) lowered mortality and heart failure worsening in high-risk older adults getting transcatheter aortic valve implantation (TAVI), the DapaTAVI trial showed. In a population with a history of.

Aortic valve 69

Aortic valve Outcomes Heart Failure Aortic 69

Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

Two years ago, the patient suffered from type A aortic dissection. As a result, partial aortic dissection artificial vascular replacement and partial aortic arch artificial vascular replacement were performed.

Aortic 52

Aortic Heart Failure Hospital 52

Open Heart

AUGUST 19, 2024

Background Aortic conduit and reservoir functions can be directly measured by four-dimensional flow (4D flow) cardiovascular magnetic resonance (CMR). Methods Twenty healthy controls (10 young and 10 age-gender-matched old controls) and 20 patients with heart failure with preserved ejection fraction (HFpEF) were recruited.

Aortic 52

Aortic Preserved Ejection Fraction Heart Failure Stroke 52

European Journal of Heart Failure

DECEMBER 11, 2024

Abstract Worldwide, valvular heart disease (VHD) is a common cause of hospitalization for acute heart failure. In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock.

Cardiogenic Shock 68

Cardiogenic Shock Heart Disease Heart Failure Bicuspid/Mitral 68

Journal of the American Heart Association

JANUARY 31, 2024

The present study sought to test the hypothesis that hypoxia is cardioprotective in left ventricular pressure overload (LVPO)–induced heart failure. The HxTAC model is resistant to cardiac hypertrophy and the development of heart failure.

Heart Failure 45

Heart Failure Aortic Heart Disease 45

Open Heart

DECEMBER 2, 2023

Objective The association between a combined anaemia and renal failure index and 1-year prognosis of patients undergoing transcatheter aortic valve implantation (TAVI) is unexplored. The primary clinical outcome measure was all-cause mortality and heart failure hospitalisation 1 year after TAVI. Cut-off values were 10.1

Aortic valve 52

Aortic valve Aortic Heart Failure Stenosis 52

Circulation: Heart Failure

JANUARY 20, 2025

Circulation: Heart Failure, Ahead of Print. The integrative physiology of the left ventricle and systemic circulation is fundamental to our understanding of advanced heart failure and cardiogenic shock.

Cardiogenic Shock 40

Cardiogenic Shock Heart Failure Circulation Physiology 40

Open Heart

SEPTEMBER 18, 2024

Backgrounds Permanent pacemaker implantation (PPMI) is one of the greatest disadvantages of transcatheter aortic valve implantation (TAVI). Methods We retrospectively analysed data from 745 consecutive patients who underwent TAVI for severe aortic stenosis from November 2013 to July 2022. vs 9.1%±9.7%; p=0.035).

Aortic valve 52

Aortic valve Pacemaker Aortic Heart Failure 52

Circulation: Cardiovascular Interventions

APRIL 7, 2025

BACKGROUND:The extent of cardiac damage has been shown to be associated with increased mortality, repeat hospitalization, and decreased quality of life after aortic valve replacement (AVR). Patients were categorized into 5 groups (stages 04) based on their stage of cardiac damage in the year before AVR.

Aortic valve 40

Aortic valve Aortic Heart Failure Quality of Life 40

Circulation: Cardiovascular Imaging

MARCH 21, 2025

BACKGROUND:Patients with paradoxical low-flow, low-gradient severe aortic stenosis exhibit low transvalvular flow rate (Q), while maintaining preserved left ventricular ejection fraction. Over a follow-up of up to 5 years, severe MR correlated with higher all-cause mortality (P=0.02) and aortic valve replacement rates (P=0.012).

Stenosis 40

Stenosis Aortic Aortic valve Bicuspid/Mitral 40

DAIC

JANUARY 5, 2024

Joint Statement on Aortic Valve Replacement in Low-Risk Patients Issued by Society of Thoracic Surgeons and European Association for Cardiothoracic Surgeons 6. STOP-CA Clinical Trial Finds Statins Lower Rate of Heart Decline in Lymphoma Patients, Late-Breaking ACC23 Clinical Trial Reports 7.

Atrial Fibrillation 105

Atrial Fibrillation Aortic valve Cardiothoracic Interventional Cardiology 105

HeartRhythm

AUGUST 31, 2024

Aortic stenosis (AS) is an increasingly common valvular disease and, if left untreated, can lead to heart failure (HF).

Stenosis 40

Stenosis Aortic Electrocardiogram Heart Failure 40

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Background A metabolic shift from fatty acid (FAO) to glucose oxidation (GO) occurs during cardiac hypertrophy (LVH) and heart failure with reduced ejection fraction (HFrEF), which is mediated by PGC-1α and PPARα. Methods Luciferase assays were performed to verify that TFEB regulates PPARGC1A expression.

Heart Failure 59

Heart Failure Cardiac Function Aortic 59

NEJM Journal Watch - Cardiology

MARCH 18, 2025

A small randomized study failed to show a benefit of TAVR in this population.

TAVR 40

TAVR Heart Failure Stenosis Aortic 40

NEJM Journal Watch - Cardiology

APRIL 9, 2025

Dapagliflozin was safe and reduced HF events soon after transcatheter aortic valve replacement in an older cohort, but it did not improve survival.

Aortic valve 40

Aortic valve Heart Failure Aortic 40

Circulation

NOVEMBER 11, 2024

Background:The positive effects of sodium glucose co-transporter-2 (SGLT2) inhibitors on reducing cardiovascular mortality and hospitalizations due to heart failure have been well established. Circulation, Volume 150, Issue Suppl_1 , Page A4115947-A4115947, November 12, 2024.

Heart Failure 40

Heart Failure Cardiac Function Myocardial Infarction Aortic 40

Cardiovascular Diabetology

FEBRUARY 15, 2024

Stress hyperglycemia ratio (SHR) has recently been recognized as a novel biomarker that accurately reflects acute hyperglycemia status and is associated with poor prognosis of heart failure. We evaluated the r.

Aortic valve 52

Aortic valve Aortic Biomarkers Stenosis 52

Journal of Cardiothoracic Surgery

JANUARY 19, 2024

We present a patient with a history of heart failure and metallic aortic and mitral valves surgeries, who required ablation for a drug-refractory left ventricular tachycardia. But the metallic valves prohibite.

Bicuspid/Mitral 40

Bicuspid/Mitral Tachycardia Aortic Ablation 40

DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

DAIC

JUNE 5, 2024

The sale enhances Edwards’ balance sheet flexibility for disciplined investments in technologies for aortic, mitral, tricuspid and pulmonic patients, as well as new therapeutic areas for interventional heart failure. Edwards will use the after-tax cash proceeds to fund strategic growth investments.

Critical Care 105

Critical Care Tricuspid Innovation Bicuspid/Mitral 105

Circulation

SEPTEMBER 18, 2024

BACKGROUND:Excitation-contraction (E-C) coupling processes become disrupted in heart failure (HF), resulting in abnormal Ca2+homeostasis, maladaptive structural and transcriptional remodeling, and cardiac dysfunction. Circulation, Ahead of Print. E-C coupling efficiency was measured by in situ confocal microscopy.

Heart Failure 40

Heart Failure Aortic Circulation Outcomes 40

Journal of Cardiovascular Pharmacology

DECEMBER 14, 2023

Abstract: Studies have examined the therapeutic effect of levosimendan on cardiovascular diseases such as heart failure, perioperative cardiac surgery, and septic shock, but the specific mechanism in mice remains largely unknown.

Aortic 52

Aortic Heart Failure Cardiovascular Disease Article 52

DAIC

JULY 31, 2024

This potential vascular market for this product family is measured in millions of procedures per year, including cardiac interventions such as structural heart procedures and electrophysiology procedures, peripheral vascular interventions including renal interventions, endovascular aortic repair, and carotid artery interventions.

Myocardial Infarction 99

Myocardial Infarction Technology Angina Pulmonary 99