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Functional assessment of coronary artery disease in patients with severe aortic stenosis: a review

Heart BMJ

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way to treat these patients is contentious.

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“One-stop” interventional therapy for quadricuspid aortic valve combined with severe coronary artery disease: a case report

Journal of Cardiothoracic Surgery

Congenital Quadricuspid Aortic Valve (QAV) malformation is a relatively rare cardiac valve malformation, especially with abnormal coronary opening and severe stenosis of Coronary Artery Disease (CAD). The pati.

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Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease

JAMA Cardiology

This genomewide association study examined specific genetic variants, pathways, and tissues associated with aortic stenosis independent of coronary artery disease in a meta-analysis of participants from 3 European cohorts.

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Endothelial MICU1 protects against vascular inflammation and atherosclerosis by inhibiting mitochondrial calcium uptake

Journal of Clinical Investigation - Cardiology

Of clinical relevance, we observed decreased MICU1 expression in the endothelial layer covering human atherosclerotic plaques and in human aortic endothelial cells exposed to serum from patients with coronary artery diseases (CAD).

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Coronary artery disease and outcomes following transcatheter aortic valve implantation

Open Heart

Background Aortic stenosis is a life-limiting condition for which transcatheter aortic valve implantation (TAVI) is an established therapy. Coronary artery disease (CAD) is frequently found in this patient group and optimal management in these patients remains uncertain.

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The Art and Science of Managing Stable Coronary Artery Disease in Patients Undergoing TAVI

The New England Journal of Medicine

Transcatheter aortic-valve implantation (TAVI) emerged as a disruptive, revolutionary approach for treating patients with aortic stenosis.1 Should we mimic.

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Large registry data demonstrate PCI for stable CAD can be safely performed before, during or after TAVR

Medical Xpress - Cardiology

New data reveal that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD).

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