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Myocardial sodium–glucose cotransporter 2 expression and cardiac remodelling in patients with severe aortic stenosis: The BIO?AS study

European Journal of Heart Failure

Bar plots: in red, patients with low flow-low gradient (LF-LG) aortic stenosis; in blue, patients with normal flow-high gradient (HG) aortic stenosis; in black: controls. Main findings of the study. p  < 0.05 for HG and LF-LG vs. control; § p  < 0.05

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Management of acute decompensated valvular heart disease

European Journal of Heart Failure

In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock. Abstract Worldwide, valvular heart disease (VHD) is a common cause of hospitalization for acute heart failure.

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Machine learning cluster analysis identifies increased 12-month mortality risk in transcatheter aortic valve replacement recipients

Frontiers in Cardiovascular Medicine

BackgroundLong-term mortality risk is seldom re-assessed in contemporary clinical practice following successful transcatheter aortic valve implantation (TAVR). k-means clustering was performed on data from 200 patients who underwent TAVR for severe aortic stenosis (AS).