Aortic, Cardiac Function and Pharmacology

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Aortic

Cardiac Function

Pharmacology

New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development

DAIC

JUNE 7, 2024

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise. These findings appear online in the journal Trends in Molecular Medicine.

Aortic valve

Aortic valve Aortic Heart Valves Pharmacology

Ovarian Tumor Domain?Containing 7B Attenuates Pathological Cardiac Hypertrophy by Inhibiting Ubiquitination and Degradation of Krüppel?Like Factor 4

Journal of the American Heart Association

DECEMBER 12, 2023

Currently, no pharmacological interventions have been specifically tailored to treat CH. Therefore, we investigated the role of OTUD7B in CH.Methods and ResultsOTUD7B knockout mice were used to assay the role of OTUD7B in CH after transverse aortic coarctation surgery.

Pharmacology

Pharmacology Aortic Cardiac Function Risk Factors

Cardiovascular Update

New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development

Ovarian Tumor Domain?Containing 7B Attenuates Pathological Cardiac Hypertrophy by Inhibiting Ubiquitination and Degradation of Krüppel?Like Factor 4

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