Frontiers in Cardiovascular Medicine

APRIL 24, 2024

Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare genetic premature aging disease that is historically fatal in teenage years, secondary to severe accelerated atherosclerosis. With this longer lifespan, calcific aortic stenosis (AS) was identified as an emerging critical risk factor for cardiac death in older patients.

Stenosis 52

Stenosis Aortic Peripheral Arterial Disease TAVR 52

Heart BMJ

APRIL 15, 2024

Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve. HU, p=0.099).

Aortic valve 52

Aortic valve Aortic Stenosis Atherosclerosis 52

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. Journal of the American Heart Association, Ahead of Print. In multivariate analysis, low CCDR (hazard ratio, 2.21 [95% CI, 0.99–4.92],P=0.04)

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. In addition, their integration with cardiovascular MRI can provide accurate risk stratification, aiding aortic valve replacement decision making.

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Stenosis Aortic Aortic valve Biomarkers 52

All About Cardiovascular System and Disorders

MAY 19, 2024

Transcatheter aortic valve replacement (TAVR) is increasing in popularity for symptomatic severe aortic stenosis. Transfemoral arterial route is the most commonly used approach for TAVR, also known as TAVI or transcatheter aortic valve implantation. No calcifications in the artery causing vascular stenosis.

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Aortic valve Aortic TAVR Open-Heart Surgery 40

Journal of the American Heart Association

FEBRUARY 23, 2024

BackgroundChronic inflammatory disease (CID) accelerates atherosclerosis and the development of aortic stenosis. Data on long‐term outcomes after transcatheter aortic valve implantation (TAVI) in those patients are missing.

Aortic valve 49

Aortic valve Aortic Outcomes Atrial Fibrillation 49

Circulation

NOVEMBER 8, 2023

BACKGROUND:High circulating levels of Lp(a) (lipoprotein[a]) increase the risk of atherosclerosis and calcific aortic valve disease, affecting millions of patients worldwide.

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Aortic valve Heart Disease Atherosclerosis Aortic 40