Remove Aortic Remove Atherosclerosis Remove Stenosis
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Disease drivers in aortic stenosis vs atherosclerosis

JAMA Cardiology

Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.

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Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome

Frontiers in Cardiovascular Medicine

Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare genetic premature aging disease that is historically fatal in teenage years, secondary to severe accelerated atherosclerosis. With this longer lifespan, calcific aortic stenosis (AS) was identified as an emerging critical risk factor for cardiac death in older patients.

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Aortic valve perivascular adipose tissue computed tomography attenuation in patients with aortic stenosis

Heart BMJ

Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve. HU, p=0.099).

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Pathophysiology, emerging techniques for the assessment and novel treatment of aortic stenosis

Open Heart

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. In addition, their integration with cardiovascular MRI can provide accurate risk stratification, aiding aortic valve replacement decision making.

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Abstract TP293: Association Between Aortic Arch Type and Lateralization of Subclavian Artery Stenosis: An Observational Cohort Study

Stroke Journal

Background and Objectives:Left subclavian artery (LSA) is more prone to atherosclerosis than the right one. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4%

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Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

Journal of the American Heart Association

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. Journal of the American Heart Association, Ahead of Print. In multivariate analysis, low CCDR (hazard ratio, 2.21 [95% CI, 0.99–4.92],P=0.04)

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. 2022 Aug, 80 (9) 934946 Kronenberg F.