Circulation

NOVEMBER 29, 2023

Circulation, Ahead of Print. BACKGROUND:Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular condition, but approved medical therapies to prevent AAA progression and rupture are currently lacking. RNA sequencing analysis showed thatST3GAL5silencing in human aortic SMCs induced ferroptosis.

Aneurysm 40

Aneurysm Aortic Atherosclerosis Risk Factors 40

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. In addition, their integration with cardiovascular MRI can provide accurate risk stratification, aiding aortic valve replacement decision making.

Stenosis 52

Stenosis Aortic Aortic valve Biomarkers 52

Circulation

NOVEMBER 8, 2023

Circulation, Ahead of Print. BACKGROUND:High circulating levels of Lp(a) (lipoprotein[a]) increase the risk of atherosclerosis and calcific aortic valve disease, affecting millions of patients worldwide.

Aortic valve 40

Aortic valve Heart Disease Atherosclerosis Aortic 40

The British Journal of Cardiology

AUGUST 1, 2024

Lipoprotein(a) (Lp[a]) can improve the accuracy of assessment of atherosclerotic cardiovascular disease and the risk of aortic valve stenosis. Currently, there is no specific treatment to lower its circulating concentration. Raised Lp(a) is a feature of familial hypercholesterolaemia.

Aortic valve 52

Aortic valve Heart Disease Blood Pressure Risk Factors 52

DAIC

JANUARY 23, 2024

1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Dr. Paddy Barrett

NOVEMBER 7, 2023

The fundamental characteristic of atherosclerosis is when a cholesterol particle becomes trapped in the artery wall. It is the inflammatory response to this particle retention that causes the formation of atherosclerosis 1. Lipoprotein particles entering the subintimal space causing atherosclerosis. CE = Cholesterol Ester.

Cholesterol 52

Cholesterol Atherosclerosis Stenosis Aortic 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Repeat CTA head and neck demonstrated multifocal intracranial atherosclerosis with marked stenosis of the left V4 segment. However, marked stenosis at V2 appeared to be owed to external compression from facet arthrosis rather than atherosclerosis. He also had moderate stenosis of the right V4 segment.

Stenosis 40

Stenosis Peripheral Arterial Disease Atherosclerosis Pacemaker 40