Remove Aortic Remove Atherosclerosis Remove Biomarkers
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Pathophysiology, emerging techniques for the assessment and novel treatment of aortic stenosis

Open Heart

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. Existing biomarkers (troponin and brain natriuretic peptide) are non-specific, but cost-effective predictors of ventricular dysfunction.

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Hepatocyte growth factor is associated with greater risk of extracoronary calcification: results from the multiethnic study of atherosclerosis

Open Heart

Background Hepatocyte growth factor (HGF) is a biomarker with potential for use in the diagnosis, treatment and prognostication of cardiovascular disease (CVD). This study examined whether HGF is associated with ECC in the aortic valve (AVC), mitral annulus (MAC), ascending thoracic aorta and descending thoracic aortic (DTAC).

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5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC) 

Cardiometabolic Health Congress

Attendees, including hundreds of health professionals, gained access to the latest knowledge and developments in the field, from exclusive insights from one of the foremost authorities on atherosclerosis, Dr. Peter Libby, to innovations like new therapeutic agents and exciting advancements in renal protection.

CME 103
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Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

Journal of the American Heart Association

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. The resulting cholesterol crystals activate the NLRP3 (NOD‐like receptor protein 3) inflammasome, leading to inflammation and cardiovascular diseases.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

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7 steps to missing posterior Occlusion MI, and how to avoid them

Dr. Smith's ECG Blog

Cardiology noted there was no STEMI criteria and the first troponin was in the normal range (25ng/L, with normal <26), so alternate diagnoses were considered and the patient was sent for CT to rule out aortic dissection. 4] CT revealed no dissection but extensive coronary atherosclerosis. In a study last year, 14.4%

STEMI 52
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The Ultimate Guide to Sleep and Cardiovascular Health

Physiologically Speaking

The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration. 13 Coronary artery calcification (CAC) and aortic stiffness are also associated with self-reported sleep duration.