Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. The resulting cholesterol crystals activate the NLRP3 (NOD‐like receptor protein 3) inflammasome, leading to inflammation and cardiovascular diseases.

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. Existing biomarkers (troponin and brain natriuretic peptide) are non-specific, but cost-effective predictors of ventricular dysfunction.

Stenosis 52

Stenosis Aortic Aortic valve Biomarkers 52

Open Heart

MAY 31, 2022

Background Hepatocyte growth factor (HGF) is a biomarker with potential for use in the diagnosis, treatment and prognostication of cardiovascular disease (CVD). This study examined whether HGF is associated with ECC in the aortic valve (AVC), mitral annulus (MAC), ascending thoracic aorta and descending thoracic aortic (DTAC).

Atherosclerosis 52

Atherosclerosis Aortic valve Risk Factors Aortic 52

DAIC

JANUARY 23, 2024

1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Dr. Smith's ECG Blog

JANUARY 3, 2022

Cardiology noted there was no STEMI criteria and the first troponin was in the normal range (25ng/L, with normal <26), so alternate diagnoses were considered and the patient was sent for CT to rule out aortic dissection. 4] CT revealed no dissection but extensive coronary atherosclerosis. In a study last year, 14.4%

STEMI 52

STEMI Myocardial Infarction Chest Pain Ischemia 52

Physiologically Speaking

APRIL 24, 2024

The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration. 13 Coronary artery calcification (CAC) and aortic stiffness are also associated with self-reported sleep duration.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52